We recently joined the @PKDFoundation community at PKDCon, which brought together people living with ADPKD, their caregivers, and family members; and the PKD Centers of Excellence, a conference for nephrologists and investigators focused on advancing standards of care. (1/5)
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We appreciated hearing from people living with ADPKD, connecting with clinicians, and sharing more about our research investigating PAPP-A. (2/5)
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PAPP-A is a protein that influences insulin-like growth factor (IGF) signaling, which may play a role in kidney cyst development and growth in ADPKD. This potential role has not been established and remains under investigation. (3/5)
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Learn more about how we’re advancing clinical research in ADPKD and our ongoing global Phase 2 trial: calicolabs.com/clinical-tria… (4/5)
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Replying to @PKDFoundation
Calico's ADPKD program is investigational. No treatment based on this research has been approved by the FDA or other governmental agency and its safety and effectiveness have not been established. (5/5) #ADPKD

Jul 13, 2026 · 3:33 PM UTC

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