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User interfaces are not going away.
Yes, humans will use computers alongside agents. When working with agents, we will need the ability to audit what agents do in a human-readable way.
Yes, some interfaces (ex: dashboards, in-chat UI for ephemeral tasks, etc) will be generated. Most important interfaces will be intentionally designed. We will want both deterministic and non-deterministic interfaces in different situations. We're thinking a lot about the best ways to help designers shape non-deterministic systems at Figma.
Yes, new input modalities like voice, VR/AR and BCI will change the way we use computers and introduce lots of new interaction paradigms. This is all very exciting :)
Overall, the surface area of design will continue to grow much broader. Design is the new code and the key differentiator for software moving forward. Expect more and more energy to go into design / craft in the years ahead... it will be how you win or lose.
Eric is right about plenty of things, but the market will prove him wrong on this one...