Ashlin Barry celebrates his birthday by becoming the first US male to win the U23 world title in a thrilling solo attack. velo.outsideonline.com/road/…

I am flying in a crowded jet above the most majestic and Biblical desert landscapes I know of -- the Colorado Plateau, home of stupendous canyons and buttes etc, with many world-class national parks -- and mine is one of only 4 open windows on the whole plane.

Multicancer early detection tests What we know/ What we don't Access vs Payment

Syncope is common, but the patient journey remains remarkably variable. Where a patient is assessed, which investigations are available and how services are organised can all influence the care they receive. Before we can improve that care, we need to understand the current landscape and agree on what good syncope care should look like. I am looking forward to the UK Syncope Survey and Care Definitions session at #HRC2026 with Miss Cristiana Monteiro, Professors David Benditt, Matt Reed and Richard Sutton, and Nigel Breakwell. This should be an important discussion about moving from variation towards clearer, more consistent pathways. 🗓️ Monday 12 October 📍 Heart Rhythm Congress 2026 #Syncope #STARS #Cardiology #PatientCare #HRC2026 @TrudieLobban

Very thoughtful piece on future of AI and echocardiography by @David_Ouyang intentionalintelligence.subs…

These letters are the tip of the iceberg of the prob w CHAMPION (and OPTION, btw) CHAMPION will be used in EBM classes as an eg of biased design and interpretation A colossal embarrassment for the academics involved Note what BSX stock did the Monday after the *positive* trial was presented cc @kaulcsmc

Published in the NEJM, three letters raise important points about CHAMPION-AF: 1) The primary endpoint includes cardiovascular death (42% of events), which is a “dilutive” component that does not characterize either treatment arm and favors a finding of noninferiority. 2) Focusing on ischemic stroke reveals a hazard ratio of 1.61 (95% CI, 1.00–2.59), with no difference in hemorrhagic stroke. This is somewhat the opposite of what one would expect from percutaneous LAAC. 3) The number of events was so much lower than anticipated that, while maintaining the same noninferiority margin, the trial effectively allowed a doubling of events while still declaring noninferiority. 4) It is inappropriate to consider the risk of intracranial hemorrhage solely as a function of oral anticoagulant exposure, while ignoring predisposing structural conditions such as cerebral amyloid angiopathy. nejm.org/doi/full/10.1056/NE…

All-In Summit: Bill Gurley (0:00) Bill Gurley takes the stage at the All-In Summit (1:29) Bill's Presentation: Searching for Feynman Links to additional resources mentioned in talk and used in research: p3.institute/searching_for_f… @bgurley

A full circle moment for Xander 😳👏 Five years after his viral video from the Tour of Britain, 17-year-old Xander Graham has signed with JEGG-SKIL-DJR junior team for 2027 which is partnered with Team Visma | Lease a Bike 🤯 📹 Xander Graham (posted with permission)

OmniaSecureリード植込み後、P波のoversensing(PWOS)による心室ペーシング抑制を来したCRTD症例をJACC EPに報告しました。 ✅Coil positionはやはり重要 ✅VSR機能はPWOSに対する安全機構およびモニタリングに有用である可能性 ぜひご一読下さい。 50日間フリーアクセス authors.elsevier.com/a/1noE3…

Honored to serve the American people on the US Preventive Services Task Force I am looking forward to advising @HHSGov on preventive health measures 🇺🇸🇺🇸🇺🇸 uspreventiveservicestaskforc… uspreventiveservicestaskforc…