The Paradisians of Paradise are a narrow genetic admixture of Anglo-Saxons and Ulster Scotts. But thanks to the tropical environment, excessive trait selections in favor of agreeability and group-think behavior, and the lack of natural resources outside of native flora and fauna, the people here are technologically repressive and despise innovation of most any kind. They are pastoralists and enjoy long lives farming and wandering through nature.
The Mutants of Epsilon Omega are a weebs wet dream and most of these denizens inhabit a single solar system of three habitable planets, Delta, Gamma and Omega. Their civilization was founded by a cabal of genetic scientists and bioengineers fleeing from Terra. Long centuries have passed since then and the Mutants have created a thriving multi-planetary civilization that is highly permissive and endlessly innovative, but extremely honor bound and almost cruel in it's expectations of its own citizenry.
The Colonites live far away from Paradise and Terra Prime; exiled revolutionaries, idealists, and philosophers turned colonists and explorers, the colonies of the Inner Spur are disunited and factional, due to hardship and exile, they are masters of innovation, navigation, and survival. To all the other races of man, they are the most baseline, though many are cyborgs and all are augmented in one way or another. It is from them that a titan has emerged, a leader of myth and legend, an ancient god from Terra Prime; one-eyed and cunning, wielding both spear and plasma cannon, wanderer and mystic, he has begun amassing an armada for his "Hunt across the Wild Sky".
Meanwhile, on the other side of the Orion Spur towards the outer darkness of the rim, the massive Homeworlders ship, Forever Last, stumbles into an ancient empire of dead planets, zombies, enslaved subhumans, and Lovecraftian cosmic monsters bent on conquering the upstart humans. Forever Last and her gallant crew must return and warn humanity of the gathering storm at their door step.
Mankind must abandon his petty squabbles and unite against the Outer Dark! Welcome to Conquered Space!