Christian, mathematician, reader, 🇺🇸. Assistant Prof at @MoffittNews: #MathOnco, cancer evolution, antifragility, cellular automata, #sciart
Tampa, Florida
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My mental model of targeted therapies:
1. Convex dose response (double the dose, get less than double response)
2. Concave resistance onset (cut the dose in half, reduce the resistance by more than half)
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My mental model of targeted therapies:
1. Convex dose response (double the dose, get less than double response)
2. Concave resistance onset (cut the dose in half, reduce the resistance by more than half)
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Read more: aacrjournals.org/cancerres/a…
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This week in Math Onco ~
Very cool artwork from Paul Newton, Matthew Giles
Based on the paper: Reinforcement learning for chemotherapy scheduling in a stochastic tumor evolution model published in Physical Review E
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Jeffrey West retweeted
Today’s @mathonco research in progress is from #AndersonLab member Daniel Camacho. Giving his 1st RIP on his 1 year @MoffittNews anniversary discussing; Economic calculation and mathematical oncology: rethinking prediction through the Austrian school.
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This week in MathOnco's artwork is pretty sweet! Made by @tbansod707, @thillen17
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Jeffrey West retweeted
First time visiting #Purdue for the #SIAM Great Lakes Section Meeting! A great selection of talks on MathBio, SciML, and Complex Systems - I spoke about agentic AI for autonomous modeling and simulation in biological systems - joint work with @mathoncbro!
purdue.edu/science/events/gl…
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I’ve worked on AI for over a year now and still managed to avoid referring to my team members as “agentic biological intelligence”
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Check out the new initiation from Bulletin of Mathematical Biology called MathBioNexus.
Live seminars, the next one entitled "Cells, bureaucracy and corruption" by Fred Adler
cassyni.com/events/S1zv5xP1X…
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I wasn't expecting agentic AI to have such a big impact on scientific manuscript rate, mainly because we are still so early. Most (?) academics still have not used AI agents.
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Guys, we did it. We survived another Florida summer.
After 95 straight days with an average high temperature of 91°, Tampa's average high dropped to 90° today. Average high will continue to slowly drop until it reaches 71° on January 4th. Baby steps to cooler weather in #Florida
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.@nancykgillis & I just published a Spotlight piece, highlighting Armel Batchi-Bouyou, Kelly Bolton et. al's interesting work on predictive modeling of clonal hematopoiesis
Original research: sciencedirect.com/science/ar…
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Jeffrey West retweeted
New in Convergence Science from the September 1 issue—Evolutionary Antifragile Therapy Is a Treatment Strategy to Suppress Drug Resistance by Exploiting Dose–Response Convexity doi.org/10.1158/0008-5472.CA… @mathoncbro @ara_anderson #MathOnco #ComputationalMethods #TumorEvolution
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This is a really neat project! It turns out ALCL is a plausible candidate for evolutionary therapy due to an exceedingly high cost of resistance to ALK inhibitors
Today’s @mathonco research in progress is by @fpradelli94 from @mathoncbro lab presenting, Dose response dynamics in Anaplastic Large Cell Lymphoma. @MoffittNews
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Jeffrey West retweeted
Today’s @mathonco research in progress is by @fpradelli94 from @mathoncbro lab presenting, Dose response dynamics in Anaplastic Large Cell Lymphoma. @MoffittNews
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Jeffrey West retweeted
Spotlight: Antifragility in Cancer!
@AmyEPomeroy & @ac_palmer wrote a Spotlight highlighting our recent mansucript on antifragile therapy dosing strategies in Cancer Research:
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