Using nucleoside-modified mRNA and nanoparticle technology to develop and optimize mRNA-based prophylactics and therapeutics.
Philadelphia, PA
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About a week later and we are still reeling over these news! An enormous congratulations to Dr. Norbert Pardi on his well-deserved promotion to Associate Professor with tenure 🎉🎉! We wish him continued success in his new role.
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Check out this article in @MolTherapy from our exciting collab with @David_RMartinez and @aschaefe29 .
Thank you to all contributors!
#mRNA #mRNALNP #Vaccine #research
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💡New Research Protocol
Expression and purification of the receptor-binding domain of SARS-CoV-2 spike protein in mammalian cells for immunological assays
🗒️buff.ly/3w5KPOn
🖋️@pardi_lab @LipinszkiLab
#Immunology #SARSCOV2 #mRNAvaccine #NeutralizingAntibodies
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An exciting collab with @LipinszkiLab ! Check out our methods paper for high-yield expression and one-step affinity purification of recombinant RBD from transiently transfected Expi293F cells! @FEBSnews
febs.onlinelibrary.wiley.com…
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A beautiful start to a new week and month! Congratulations @kkariko and @WeissmanLab
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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The Pardi Lab retweeted
So grateful to get to spend time with these two gems (@pardi_lab & Phil Felgner) at the Keystone Next-Generation Nanomedicine conference this week! Couldn’t ask for better co-organizers or speakers. What an exciting field 😀
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We are thrilled to be part of the Next-Generation Nanomedicine Conference! Check out @KeystoneSymp for more details on on-site and virtual meeting details.
NMIN is a proud sponsor of the online Next-Generation Nanomedicine Conference, 6-8 Sep 2023 @AnnaBlakney @pardi_lab @KeystoneSymp
Info & register: keystonesymposia.org/confere…
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The Pardi Lab retweeted
Development of an mRNA-lipid nanoparticle vaccine against Lyme disease #genetherapy #celltherapy dlvr.it/St6r4D
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A huge congratulations to Matt Pine for his recent publication in @MolTherapy - an OspA mRNA-LNP vaccine against Lyme disease that induced superior humoral and cell-mediated immune responses in mice after a single immunization!
#LymeDisease #mRNA #vaccines
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Naomi Meyer learns more about #mRNA technology in the Pardi Lab!
In just a week, high schooler, Naomi, got a glimpse of what it means to be a researcher. “Interesting, exciting and enlightening!” summarizes her experience in the lab.
#inspiringyoungminds
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The Pardi Lab retweeted
Matthew Pine from the Pardi @pardi_lab & Weissman @WeissmanLab labs defends tomorrow!
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A truly inspiring seminar by @kkariko punctuated by good laughs and gems on how to keep the science going. Thank you!
Three generations Hungarian American scientists at @PennMedicine. @kkariko @pardi_lab Incredibly powerful lecture at @PennMicro on the discovery of mRNA therapeutics, grit, determination, incredible and genuine excitement for #science
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We are excited to hear @kkariko share the story of "Developing mRNA for therapy" at the annual Neal Nathanson Lecture this Wednesday, May 3rd at noon! Join the seminar in-person or online!
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We are excited to share our former visiting graduate student’s, Jamile Ramos da Silva, recent publication in @ScienceTM . Thank you to all our collaborators, and congrats Jamile!
Read on here: science.org/doi/abs/10.1126/…
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The Pardi Lab retweeted
We just published another flu mRNA vaccine study in @JVirology, where we show how the mRNA vaccine platform can improve seasonal influenza vaccines. 1/2
journals.asm.org/doi/10.1128…
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Check out this wonderful collaboration with Koen van de Ven and colleagues from RIVM, Netherlands. Our findings show that combined flu mRNA T cell vaccine induced protective immune responses in ferrets. science.org/doi/10.1126/scia…
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The Pardi Lab retweeted
Just published in Science Magazine @ScienceMagazine - A multivalent mRNA vaccine against all known influenza virus subtypes. Congratulations to all the researchers!!! @SCOTTeHENSLEY @WeissmanLab @MgAlameh @pardi_lab @PennMedicine
science.org/doi/10.1126/scie…
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What an exciting and informative introduction to the 2022 mRNA Health Conference. Follow
@mrnaconference to learn more!
#mRNAhealthconference
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The Pardi Lab retweeted
Ever wonder how mRNA vaccines stimulate strong immune responses without an added adjuvant? Find out in this brand new review article I contributed to on the innate immune mechanisms of mRNA vaccines! authors.elsevier.com/c/1g2oW…
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Interested in learning more about immune sensing of mRNA vaccines? Check out this paper written with fantastic colleagues, @rein_verbeke , Karin Lore and @MikeHoganPhD .
cell.com/immunity/fulltext/S…
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