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Every good defence needs a backup ๐ก๏ธโ๏ธ
Out now in @NatureRevMicro our Comment on "๐ถ๐บ๐บ๐๐ป๐ฒ ๐๐ฎ๐ณ๐ฒ๐ด๐๐ฎ๐ฟ๐ฑ๐ถ๐ป๐ด"! ๐
๐ nature.com/articles/s41579-0โฆ
Jul 21, 2026 ยท 8:25 AM UTC
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A growing number of bacterial immune pathways sense phage (virus) disruption/evasion of primary defences and trigger abortive infection ๐ก๏ธ๐ฅ
This hierarchical defence organisation is a conserved immune principle, from bacteria ๐ฆ to plants ๐ฑ & animals ๐
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Why? The result is a double bind for viruses ๐ชค: disable the 1st line of defence, and you trip the 2nd!! โ ๏ธ
More ideas & open questions in the article ๐๐ค
Full-text link ๐: rdcu.be/fucyj
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Such a fun piece to write with David Mayo-Muรฑoz, @LeiseRiber & Eugene Koonin!! ๐๐งฌ
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