Clinical trials in psychiatry rely on measures of symptomatology, not biology. This @ACNPorg position paper lays out why validated biomarkers in psychiatry have lagged behind fields like Alzheimer's and ALS, and what it will take to close the gap: precompetitive data sharing, standardized protocols, & earlier FDA engagement. nature.com/articles/s44277-0…

One week left to apply for our Editors’ New Investigator Award ⬇️⬇️⬇️ nature.com/dpn/announcements…

BREAKING: President Trump Signs Executive Order to Accelerate Psychedelic Research and Access This is a breaking story. More to follow.

Excited to read this preprint by @YiZuoUCSC, using 2p imaging to track spines following psilocybin. Many similarities with our findings. The new study crucially also tested dose dependence and dived deep into spine characteristics like clustering. 👉 biorxiv.org/content/10.64898…

Learn more about the recent cohort of recipients of DPN's New Investigator Award, and apply by May 18th!

Very cool structural biology and molecular pharmacology study on psychedelic mechanisms of action. But, I cringe at references to hallucinations in mice, even with qualifiers about limitations of animal models. We need to be more precise in our descriptions of animal behavior!

This Award offers eligible early independent investigators a waived article processing charge ($2,190) to support open access publication of their original work in DPN. See link for more details and stay tuned for the next call for papers! nature.com/dpn/announcements

🌟Announcing the next cohort of the DPN Editor’s New Investigator Waiver Award recipients🌟 Dr. Nicole Zürcher, MGH/@harvardmed Dr. Jennifer Goldschmied, @Penn Dr. Sarah Sperry, @DrSarahSperry @UMich Congratulations! We're proud to support your work👏

The sleeping brain influences the waking mind. This was a fun one. A brief one-stop shop to sleep theory, measurement, and interpretation, with a focus on the EEG and its relevance to psychiatric research. Hope it's useful! @BrownPsychiatry @BradleyHospital

Our new Deep Dive covers a study by @Auerbach_Lab_CU @DPagliaccio @CarterFunkhous1 & colleagues, which linked EEG-based brain connectivity patterns with emotional expression from text messages to identify neural markers of depressive symptoms in teens piped.video/a_yXb3wERfo

Recapping the #ACNP2026 study group, “Centering Lived Experience in Psychiatric Neuroscience Research” We asked the panelists, what could NIH leadership do to be more supportive of trainees with non-traditional career paths, which is common among researchers with lived experience of mental illness?

Our latest Deep Dive covers a study that developed a deep learning model to classify sleep stages from single channel EEG recordings in rats🐀. It predicted key parameters of sleep architecture, reducing the need for labor-intensive manual annotation. piped.video/kEgCbyqC0jU?si=0qsw…

We're interested in hiring a post-baccalaureate research associate to work in circuit and systems neuroscience studies of anxiety. Please reach out - my email is listed at kayelab.com - if interested or share with undergraduate/recent grads who may be interested.

Recent US data shows overdose deaths involving both synthetic opioids & stimulants rose from 2018 until 2023, then declined sharply in 2024, driven by decreases in opioid-involved deaths. Despite recent declines, polydrug overdose mortality remains high nature.com/articles/s41386-0…

First ACNP is going to be tough to top! Thanks to everyone who stopped by to learn about @dpn_journal 🫶🏻🧠💻 #acnp2026

Thank you all for an unforgettable #ACNP2026 full of cutting-edge science, insightful discussions, and positive energy! See you next year in San Diego for #ACNP2027!

Last day of #ACNP2026! Head over to Poseidon III-IV this morning from 9-11 to hear about how cross-species functional brain biomarkers are being used to improve translation and facilitate drug development in psychiatry 🧠

🥁🥁The top 3 winners of #ACNP2026 Trivia are🥁🥁 1. Christine Ann Denny, @DrChristineAnnD 2. Catharine Mielnik 3. William Stoops, @WilliamStoops Congratulations and thank you for participating! 🎉🧠

Thinking about whether you should promote your next research paper on X, Bluesky, or *Reddit*? Stop by @brittonrae5’s poster #1 tonight at #ACNP2026 to learn about how these 3 platforms differ in terms of engagement and online attention driven by posts about DPN articles.

Hey #ACNP2026 👋 Are you interested in serving as a reviewer for @dpn_journal and @npp_journal? Scan this QR code to fill out a form and tell us more about yourself!