News from the 23andMe Research team on #Genomics #Genetics #GWAS #PheWAS #DrugDiscovery @23andMe for product updates | RTs ≠ Endorsement
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What is possible when participants power research
In a new collaborative study publish in @ScienceMagazine today, researchers at 23andMe and @DanaFarber used data from more than 3.3 million 23andMe consenting research participants to characterize a rare inherited EGFR variant that significantly elevates lung cancer risk, while also exploring its relationship to smoking, polygenic risk, ancestry and geography.
We found that the EGFR T790M genetic variant is carried by about 1 in 15,000 people in the United States, and is associated with a 25-fold increased risk of lung cancer. Among people who never smoked, carriers had a 60 fold higher odds of developing lung cancer than non-carriers.
Illustration credit: @oliveruberti
Learn more about the study and work here: 23andme.org/blog/articles/eg…
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Cool new paper by scientists from @23andme @smithsonian, and @harvard that combines genetic and genealogical info to propose identities for previously unknown individuals buried in St. Mary’s City cell.com/current-biology/ful…
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23andMe Research retweeted
Genomics of GLP-1 drug response and side effects
With genomic and demographic data it's possible to predict magnitude of weight loss response @23andMe nature.com/articles/s41586-0…
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Congrats to our team and our research participants on these exciting findings. Just one example of the impact we hope to have as a non-profit research organization.
Published in @Nature today, new research from the 23andMe Research Institute identifies genetic variants that may help explain why GLP-1 medications work differently based on genetics.
Read the announcement: 23and.me/4skua0U
#GLP1 #Genetics #PrecisionMedicine #Research
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Want to learn about genetics or help someone else learn? Check out our genetics learning hub:
education.23andme.com/
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We’re at @PMWCintl this week! Join us as we discuss the shift from reactive to proactive healthcare. Stay tuned for insights from our founder Anne Wojcicki who will be speaking on the panel “Scaling Meaning: When Measurement Meets Biology at Scale," happening Friday.
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Most people with a medically actionable genetic variant identified through 23andMe were previously unaware of their genetic risk. 82% had no prior clinical genetic testing for that variant, even though 68% reported a personal or family history of a related health condition.
When people learn about a serious genetic risk, do they ignore it or take action?
In a new study published in Genetics in Medicine Open, the 23andMe Research Institute looked at what members did after learning they had an increased genetic risk.
blog.23andme.com/articles/23…
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What does your DNA say about your behavior? 🧠🧬 A 12-year collaboration between @23andMe and researchers at @UCSD is finding the answers thanks to the power of crowdsourced data with rigorous ethical standards blog.23andme.com/articles/a-…
#Genetics #BehavioralScience #DNA
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Today, researchers published a new study identifying 58 independent genome-wide significant risk variants for anxiety, using data from more than 3 million consented 23andMe research participants to replicate the findings. Learn more here. #Genetics #AnxietyResearch #23andMeResearch
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Join us in revolutionizing research engagement with the largest recontactable genetic research cohort in the world:
23andme.wd5.myworkdayjobs.co…
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Check out our blog post looking back at our research from 2025 and looking forward to where we think things are going in 2026: blog.23andme.com/articles/lo…
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We're hiring a product manager lead to help us make a bigger impact with our research:
23andme.wd5.myworkdayjobs.co…
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Come help build the non-profit 23andMe Research Institute forward as our first leader in philanthropy:
23andme.wd5.myworkdayjobs.co…
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23andMe Research retweeted
We're hiring! We're seeking a talented statistical geneticist to join the team. Come work with the greatest genetic dataset in the world, and help shape the 23andMe Research Institute in our nonprofit era!
23andme.wd5.myworkdayjobs.co…
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We're thrilled to introduce #PRSformer. It will be presented at #NeurIPS2025 on Dec 3 in Poster
Session 1 from 11am-2pm PT. PRSformer is a transformer-based AI model for disease-risk
prediction from individual-level genetics.
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Our key insight is that the power of non-linear models to predict disease risk starts to unlock at the million-sample scale. This work advances AI-driven insights into how your unique genetic code shapes health.
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Preprint Paper: biorxiv.org/content/10.1101/…
Github: github.com/23andMe/PRSformer
Looking forward to sharing in San Diego at NeurIPS 2025
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"Learning about a genetic predisposition to depression is psychologically well tolerated among those with high polygenic risk scores" by our own Becca Berns today at #ashg2025 2:30-4:30 poster 3014F
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Check out our Explore23 poster presented by Julie Granka (poster 2035T) from 2:30-4:30pm at #ASHG2025 to learn about this portal into our research dataset
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