The Asangani Lab at the University of Pennsylvania; we study Transcriptional Addiction in Cancer.

Philadelphia
Asangani Lab is funded again by DoD. This time DoD Idea Expansion award to study the PP2A-AR axis in refractory prostate cancer. 😀
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The University of Pennsylvania @PennMedicine Department of Cancer Biology @Penn_CBIO seeks MD and/or PhD candidates for multiple tenure track positions at the Assistant Professor level. Applicants with expertise in any specific area of CBIO are encouraged. apply.interfolio.com/96881
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Irfan Asangani retweeted
The @AsanganiLab is looking for a postdoc in Cancer Epigenomics and Transcriptional Addiction - learn more about the position at the link below and come join a great team! bit.ly/2Sxm2ip
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Irfan Asangani retweeted
If you are refusing to get vaccinated against COVID-19, maybe it's because you are getting your medical advice from news pundits, fearmongers, conspiracy theorists, and other deeply misinformed people, rather than from Medical Professionals.
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Irfan Asangani retweeted
Many thanks to @AsanganiLab @CD_AACR View: p300/CBP inhibition, CCS1477. A novel therapeutic approach for AR-addicted advanced prostate cancer. cancerdiscovery.aacrjournals…
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Our COVID-19 paper is out in iScience (Cell Press). Extremely proud of first authors @deng_qu @Reyazrasool and Ram Natesan for their contribution to this critical pandemic-related work. #COVID19 #ACE2 #TMPRSS2 @PennMedicine @PennEpiInst @PCFnews cell.com/iscience/fulltext/S…
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Excited to share our new study on Ewing Sarcoma (EwS). Here we discover stereociliary protein LOXHD1 as a novel oncogene and a potential tumor antigen in EwS. biorxiv.org/content/10.1101/… #sarcoma #immunotherapy #enhancer @GrunewaldLab @deng_qu @biorxivpreprint
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Irfan Asangani retweeted
Just learned we received funding from @theNCI #BeauBidenCancerMoonshot to study lineage plasticity in prostate cancer! Looking for talented post-docs to drive this project @UMRogelCancer! Please apply and re-tweet! @PCF_Science @UrologySBUR @AmerUrological @UmichCancBio @UMich
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Irfan Asangani retweeted
Congratulations to Dr. Irfan Asangani, PhD @AsanganiLab of University of Pennsylvania @PennEpiInst a recipient of our 2020-2022 Conquer Cancer Now Award #grant for their #CancerResearch project in #ProstateCancer #Immunology concernfoundation.org/donate… Or TEXT CONCERN to 77948
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Excited to share our new story on COVID-19. Our results have implications for understanding male bias in COVID-19 severity and mortality, and provide a strong rationale for androgen deprivation or anti-androgen therapy in men with SARS-CoV-2 infection. biorxiv.org/content/10.1101/…
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Irfan Asangani retweeted
Excited to share our story "Cell Cycle Checkpoints Cooperate to Suppress DNA and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses". Really a team effort to make it happen @RogerRogergr @brokendna Big thanks to our collaborators @andyjminn @AsanganiLab
Congratulations to Jie and Shane on their new paper, "Cell Cycle Checkpoints Cooperate to Suppress DNA and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses" cell.com/cell-reports/pdfExt…
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Irfan Asangani retweeted
Our paper is out, finally. Congratulations to first authors, @ritika0107 & @ManzarNishat, coauthors, collaborators @NallasivamPala4 @mishabeltran @AminaZoubeidi @FKhaniPath. Thanks to @India_Alliance for funding. Thanks @DBTIndia @serbonline @IITKanpur nature.com/articles/s41467-0…
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Irfan Asangani retweeted
Epigenetic Regulation of Chromatin in Prostate Cancer. 𝘼𝙙𝙫 𝙀𝙭𝙥 𝙈𝙚𝙙 𝘽𝙞𝙤𝙡. ncbi.nlm.nih.gov/pubmed/3190… #ProstateCancer @AsanganiLab bit.ly/2R4E5IL
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Our chapter on PCa #metabolism. Part of a new book-"Prostate Cancer--Cellular & Genetic Mechanisms of Disease Development and Progression" edited by @scottdehm +Don Tindall. Other great contributions from @AminaZoubeidi @drleighellis @DrSpratticus @quimmateo @AsanganiLab +more
Prostate Cancer Energetics and Biosynthesis. 𝘼𝙙𝙫 𝙀𝙭𝙥 𝙈𝙚𝙙 𝘽𝙞𝙤𝙡. ncbi.nlm.nih.gov/pubmed/3190… @DanielFrigo #ProstateCancer bit.ly/37KStN0
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Irfan Asangani retweeted
excited to see our paper @nature today! We showed how gain-of-function mutations in chromatin reader ENL work to drive Wilms tumor. Fantastic collaborations with many great colleagues in Allis Wen @TjianDarzacq Roeder @Muirlab @KentsisResearch Li labs! nature.com/articles/s41586-0…
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Irfan Asangani retweeted
Excellent News & Views on our paper out in Nature! We find alcohol metabolites attach to brain chromatin and affect learning! @berger_lab @PennEpiInst @PennMedNews @PennIDOM @SinaiBrain @MountSinaiPsych check it out: nature.com/articles/s42255-0…
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Irfan Asangani retweeted
Interested in studying cancer epigenetics? Our new lab at UPenn has openings for postdoctoral scientists, students, and research assistants. check out lilingwanlab.com/open-positi… for more information and how to apply.
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Irfan Asangani retweeted
Congrats to @WellenLab, @AsanganiLab, and the Marmorstein lab for receiving an AFCRI Discovery Pilot Grant for a collaborative project entitled “Probing the metabolism-epigenetics link as a therapeutic target in prostate cancer” 🎉🎊🙌🏽
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