Ashkar Lab@Ashkar_Lab

Investigating the role of NK cells in cancer and viral infection. Account run by lab members. @McMasterU @MacImmunology

ashkarlab.com
Joined November 2019
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ashkarlab.com
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More people are turning to cannabidiol (CBD) cannabis strains to help with the side-effects of pregnancy. A new study from @McMasterU has uncovered the potential risks, which includes impaired fetal growth. @MGD_CMCR @CIHR_IRSC @InnovationCA ow.ly/BLHM50UV44z

Cannabis and pregnancy: Study reveals potential risks of CBD, THC

Cannabidiol (CBD), the component in cannabis often used for therapeutic treatments, is increasingly being used during pregnancy as a means of managing symptoms such as nausea, anxiety and sleep....

healthsci.mcmaster.ca
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We are thrilled to announce that our study investigating the impact of oral cannabis consumption on pregnancy outcomes and fetal development is now published at @eBioMedicine part of Lancet Discovery Science ! This work was led by our talented previous student, Tyrah Ritchie!✨
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We found that oral consumption of cannabis during pregnancy led to impaired maternal artery remodelling and restricted fetal growth development in mice. Further, detrimental consequences were long-lasting as offspring showed behavioural changes later in life.
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You can check out the paper here: authors.elsevier.com/sd/arti…
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Join us next Thursday for visiting speaker Dr. Ali Ashkar from @McMasterU. Interferon Types and Time Matter is the discussion topic. @Ashkar_Lab @UM_RadyFHS @um_research
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Another year, another victory! Ashkar lab wins best Halloween costume for the fifth year in a row 🎃🎃
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Ashkar Lab retweeted
Waggoner Lab@LabWaggoner
27 Oct 2024
While CD56 expression could be used to indicate a hyper-functional state of NK cells, it does not directly influence the anti-tumor functions of expanded NK cells @jlb_journal Congrats, @Ana_LPortillo! @Ashkar_Lab doi.org/10.1093/jleuko/qiae2…

CD56 does not contribute to the antitumor, tissue homing, and glycolytic capacity of human NK cells

CD56 does not directly dictate the functional outcomes of human NK cells.

academic.oup.com
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Enjoying #Cytokines2024 and explore the beautiful city of Seoul! @LizBalint @Emily_YF_Feng @Ana_LPortillo
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Why does covalency matter? Here we develop a new covalent #inducedproximity system that activates T cell tumoricidal function through stabilized ternary complexes. Covalency is observed to uniquely enforce immune receptor activation signaling events! doi.org/10.1016/j.omton.2024…
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Check out the latest issue of Immunological Reviews on innate immunity (with an adaptive twist!) where @JosefowiczLab and I convinced a bunch of talented colleagues to contribute. onlinelibrary.wiley.com/toc/…

Special Issue: Innate Memory (NK cells, macrophages): Immunological Reviews: Vol 323, No 1

Immunological Reviews is a dedicated immunology journal for all areas of immunological research: clinical, experimental, and studies of allergy and the immune system.

onlinelibrary.wiley.com
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Our PhD students were awarded @machealthsci Plenary Awards! Congratulations to @Emily_YF_Feng for an Outstanding Achievement Award and to @LizBalint and @Ana_LPortillo for Publication Awards!
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Congrats to our PhD candidates for their poster awards at this years #CSI2024 @Ana_LPortillo @Emily_YF_Feng and @LizBalint for her first place poster award! @MacImmunology
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Enjoying the slopes before some science! See you at #CSI2024 @CdnImmunol
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We are super proud to announce that three of our students have been awarded external awards! 👏 Congrats to Amelia and Alexa for winning CGS-M awards! Congrats to Misaal for wining an OGS award to support the second year of her MSc!
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Ashkar Lab retweeted
Mina Sadeghi@minasadeghii
3 Apr 2024
Excited to share my very first publication! Thanks Maz for giving me the chance to write about innate immune memory- a new concept to us, but an ancient phenomenon.
Maziar Divangahi@MazDivangahi
3 Apr 2024
"Discovering adaptive features of innate immune memory" In this review with super talented @minasadeghii we discuss how evolutionary, mitochondria and cellular metabolism along with diverse signaling pathways shape innate memory responses. doi.org/10.1111/imr.13328
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Long Presentation Winners: 1st place: @LiamERondeau 2nd place: Ana Portillo 3rd place: Ann Kuganathan
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Our latest review is now available at Immunological Reviews! We discuss how "Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment". Congrats to co-first authors Adnan Moinuddin, Sophie Poznanski, and @Ana_LPortillo!
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onlinelibrary.wiley.com/doi/…
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Congratulations to our PhD student for their recents awards! 🥳 @Emily_YF_Feng was awarded a CSI Travel Award and the MIRC Travel Award! @Ana_LPortillo was awarded the W.E. Rawls Memorial Scholarship and the Alyssa Vito Scholarship in Cancer Research! 👏
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