Betts Lab retweeted
Congratulations to @carlhjune (@PennPathLabMed), @kkariko (@PennNSG) & @WeissmanLab (@PennMedicine) on being named to the @Forbes list of top 250 living innovators! tinyurl.com/34mxafsk
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Betts Lab retweeted
A new #mRNA-LNP approach can target and reprogram cytotoxic effector T cells in vivo in preclinical models, highlighting the potential for future treatments against infection, cancer, and autoimmunity. @angelarcorrigan @BettsLab @WeissmanLab
scim.ag/3Rn2WtM
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Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset biorxiv.org/content/10.1101/…
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Betts Lab retweeted
hello i published this paper today
proud of this one - it truly turned out cooler than even the most optimistic version of myself thought it would when the project started
also i'm defending in 2 days so if you don't feel like reading just come hear me tell you about it! 🙂
New paper out of the lab today from @karenwong1013 - we show that a subset of growth factor-responsive gene activation requires the nuclear kinase MSK2, which phosphorylates H3K9me2S10 at enhancers of these responsive genes prior to their transcription.
science.org/doi/10.1126/scia…
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Betts Lab retweeted
Thrilled to unveil our review on "Human circulating and tissue-resident memory CD8+ T cells," published in @NatImmunol.
nature.com/articles/s41590-0…
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Announcing an available postdoctoral position, focusing on bioinformatic analysis in the context of human viral infection and autoimmunity! Please contact us at bettslab.org or apply to the following posting: med.upenn.edu/apps/my/bpp_po…
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Our latest paper just published @NatImmunol: First single cell ATACseq-based definition of HIV reservoirs ex vivo! nature.com/articles/s41590-0…
Congratulations to Vincent Wu @vincewu9 and Laura Vella @LauraVella17
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Extensive heterogeneity of the HIV-1 infected CD4+ T-cell reservoir revealed by single-cell viral ASAPseq biorxiv.org/content/10.1101/…
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Betts Lab retweeted
New work from us. Identification of functional resident memory CD8+ T cells against SARS-CoV-2 in tonsils collected prior to the pandemic. The same type of responses are not found in blood. Location matters! science.org/doi/10.1126/scii…
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I came so close to being famous last week! I am the “Doc” he referred to in the audience during his speech. I speak, I get heckled. He speaks next and gets in Newsweek. Maybe next time I will wear my Gritty costume. newsweek.com/dad-school-boar…
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More great work from the Penn COVID research team! Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19 immunology.sciencemag.org/co…
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Betts Lab retweeted
Very excited that our paper on pre-existing cross-reactive SARS-CoV-2 antibodies is out now in @CellCellPress! Here is an excellent summary of our findings by @SCOTTeHENSLEY. Grateful for being able to do team science during a pandemic @PennMedicine
1/ Our paper showing that ~20% of humans possessed non-neutralizing antibodies against SARS-CoV-2 prior to the COVID-19 pandemic was published today @CellCellPress.
cell.com/cell/fulltext/S0092…
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Betts Lab retweeted
Pleased to share our co-authored report that resulted from a collaboration between nPOD (UF) and HPAP (UPenn) contradicting the original findings by Hamad et al. TCR /BCR dual-expressing cells and their associated public BCR clonot... sciencedirect.com/science/ar…
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After a year in review at Cell, finally have this published! Congrats Alberto!
TCR /BCR dual-expressing cells and their associated public BCR clonot... sciencedirect.com/science/ar…
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Betts Lab retweeted
Out now! A core signature that defines #human #tissue-emigrant CD8+ #Tcells under homeostatic conditions. bit.ly/3rCMgx9 @marcus_buggert @karolinskainst
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The Identity of Human Tissue-Emigrant CD8+ T Cells cell.com/cell/fulltext/S0092…
Congratulations to the entire team here for a 5 year long project that will redefine how we think about CD8+ T cell immune surveillance!
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