Supported by @NIH, the NIH Pragmatic Trials Collaboratory is advancing the design, conduct, and dissemination of pragmatic clinical trials.
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📣 In this week's PCT Grand Rounds, Corey Bills of @CUMedicalSchool will discuss the PACT-ARROW study, which uses a master protocol for trials of prevention and treatment of infected traumatic wounds in hospitalized patients in Ukraine. Join us! #pctGR
🔗 duke.is/pctnews20260921
ALT NIH Pragmatic Trials Collaboratory - Rethinking Clinical Trials Grand Rounds - "Research During Active War in Ukraine: Experiences From the PACT-ARROW Study" - Corey Bills, MD, MPH; University of Colorado
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📣 Don’t miss the new 4-part educational podcast series demystifying embedded pragmatic trial design from @Collaboratory1. Episode 1 sets the stage with NCCIH Director Wendy Weber and NIH Collaboratory co-PIs @texhern and Lesley Curtis.
🔗 Listen now: duke.is/pctpod
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The NIA IMPACT Collaboratory, a program advancing pragmatic trials of interventions for people living with #dementia, is seeking applicants for its 2027 Health Care Systems Scholars Program.
9/25: Info webinar 🧑🏽💻
11/5: Letter of intent 📩
Learn more ➡️ duke.is/pctnews20260917
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📣 In this week's PCT Grand Rounds, @ErikaRangelMD of @harvardmed will present “The 4th Trimester Initiative: A Randomized Controlled Trial of Support for Childbearing Medical Trainees.” Join us! #pctgr
🔗 du.ke/pctnews20260916
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📣 In this week's PCT Grand Rounds, @RZarychanski of @umanitoba will present “Embedded Trials in a Learning Health System: A Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery.” Join us! #pctgr
🔗 du.ke/pctnews20260909
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Access our complete collection of pragmatic trials learning modules, videos, tools, workshop materials, and the Rethinking Clinical Trials Grand Rounds archive through our training resources portal.
Learn more ➡️ duke.is/training
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In an analysis from the Nudge study, the per-patient cost of text message reminders suggests that medication adherence support via mobile messaging may be a low-cost solution for healthcare systems.
Learn more ➡️ du.ke/pctnews20260903
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📣 In this week's PCT Grand Rounds, Haider Warraich of @ARPA_H will present “Evaluating Clinical Agentic AI.” Join us! #pctgr
🔗 duke.is/pctnews20260826
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A new article from NOHARM, an NIH Collaboratory Trial, describes strategies and challenges for posttrial sustainment of pragmatic trial interventions. duke.is/pctnews20260825
ALT Headshot of lead author Shrithra Gayathri alongside a screenshot of the article
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The LungSMART team has proposed a framework for assessing the fit of custom large language models in public health interventions. The framework can guide assessments of an LLM’s performance before deployment into real-world practice.
Learn more ➡️ duke.is/pctnews20260820.
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📣 In this week's PCT Grand Rounds, @ekoermann of @nyulangone and @nyuniversity will present “Off-Label Intelligence: Books, Language Models, and AI as a Medical Device.” Join us! #pctgr
🔗 duke.is/pctnews20260819
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In a new episode of the NIH Collaboratory Podcast, Alison Huang and Derek Angus consider the potential of @JAMAplusTrials as a platform and a forum.
🔗 Listen and subscribe: duke.is/pctpod
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ICYMI Registration is now open for our virtual workshop, "Endpoint Strategy in Pragmatic Trials: From Big Questions to Meaningful Outcomes." #biostatistics #pragmatictrials #clinicalresearch duke.is/2026-nih-virtual-wor…
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📣 In this week's PCT Grand Rounds, Christopher Lindsell, Lloyd Michener, Justin Moore, Boris Volkov, and Reuben Adatorwovor will present “Designing for Impact: Introducing Translational Design Studies.” Join us! #pctgr
🔗 duke.is/pctnews20260812
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We recently spoke with investigators Rachel Winer, Amanda Petrik, and Jasmin Tiro about the the STEP-2 pragmatic trial's partnership with community health centers and Medicaid health plans to expand access to #HPV self-testing for cervical cancer. duke.is/pctnews20260811
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In a new article in @JAMIA_Open, investigators from the NIH Collaboratory Trials report on their experiences using computable phenotypes with real-world data in pragmatic trials.
Learn more ➡️ duke.is/pctnews20260810
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A secondary analysis from the INSPIRE trials found that an antibiotic stewardship program with automated prompts to deliver patient-specific risk information to clinicians reduced unnecessary use of extended-spectrum antibiotics in patients with cancer. duke.is/pctnews20260806
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📣 In this week's PCT Grand Rounds, Sreek Vemulapalli of @DukeHealth and Ricardo Henao of @DukeU will present “ADAPT-CEC: AI for Clinical Event Adjudication and Implications for Clinical Trials.” Join us! #pctgr
🔗 duke.is/pctnews20260805
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In a qualitative study, the APA-SM team gained insights from research partners in rural areas to refine the trial's smartphone-based intervention for self-management of chronic musculoskeletal pain. #ruralhealth #NIHHEALinitiative duke.is/pctnews20260803
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