P4 is the first large RCT investigating the value of CT-guided PCI We will present the results at the @TCTMD Late Breaking Clinical Trial session @crfheart @GEHealthCare @Heartflow

Original Article: Complete Revascularization Guided by Functional Coronary Angiography in STEMI (AIR-STEMI trial) nej.md/456gAFu #Cardiology

🚨 Just 50 days until the biggest names, boldest ideas, and most important breakthroughs in cardiovascular medicine take center stage. The conversations shaping tomorrow start at #TCT2026. Register now and be part of it!🚀🫀 ow.ly/9VW650ZMnt5 #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD

📣Just Announced: A Conversation with Jason Sudeikis at #TCT2026! Join the Emmy-winning actor, comedian, writer, and producer for an unforgettable session exploring leadership, resilience, teamwork, and the power of human connection. This is one session you won't want to miss! ✨ ow.ly/Q8uc50ZKGYR #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD

Call for Science is OPEN! 📢 Give your groundbreaking work the platform it deserves at #TCTAfrica2027 and make your mark on the future of interventional care. 🔬 Scientific Abstracts 📅November 9 | 2:00 PM EST 🏥Challenging Cases 📅 November 9 | 2:00 PM EST 💡TCT Plus Africa Shark Tank Innovation Competition 📅 November 11 | 2:00 PM EST Submit your work today! 👉 ow.ly/ucnn50ZJ0Se #CardioX #CardioTwitter #CardioEd #CardioResearch @tctplusafrica @jgranadacrf @triciarawh @djc795 @ColletCarlos @mirvatalasnag @kalazizimd @malbag1 @ahmedelguindy @yassersadeknhi @lieslzuhlke @TCTConference @TCTMD

A major milestone for the P5 OPTIMAL trial: the first patients have now been randomized in the U.S. P5 is exploring a new paradigm for the assessment and management of coronary calcium before complex PCI, using #CCTA to guide treatment planning and calcium modification strategies. Congratulations to the Minneapolis Heart Institute @MHIF_Heart, @yadersandoval @ManosBR and team for becoming our first U.S. enrolling site and for being at the forefront of innovation and clinical care. @jcspratt @crfheart @Heartflow @ShockwaveIVL @GEHealthCare #PCI #CoronaryCalcium #CardiacCT #CCTA

Back To The Future (Again) For FFR! 5-year FAME-3 data reassert the importance of functionally complete revascularization after PCI for the best outcomes. Much like AIR-STEMI, FAME-3 tells us that “unnecessary” PCI in stable 3-vessel CAD comes with a penalty. 👉🏼 This is the Goldilocks problem of PCI - too many or too few DES both negatively impact outcomes! Physiology guided PCI is the key to getting it just right!🧐 @Hragy @ihtanboga @mirvatalasnag @mmamas1973 @ziadalinyc @DrSiyabMD @ColletCarlos @rajivxgulati

WOW! Sham #AFib ablation RCT…. neutral

🚀 75 days until #TCT2026! 🌎 Thousands of Attendees 🎓 Hundreds of Faculty ✨ Endless Opportunities to Learn, Connect, and Be Inspired! Get ready for breakthrough science, practice-changing research, cutting-edge technology, hands-on learning, and the unmatched energy of the global #interventionalcardiology community. Secure your spot before rates increase on September 2! ow.ly/ZRk350ZAtCu #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD

🚀 The Coronary Track is now live for #TCT2026! Discover breakthrough science, cutting-edge PCI techniques, and expert-led discussions from leaders in coronary intervention. 🔍 See what's shaping the future of coronary care and start planning your experience today. ow.ly/NMuG50Zz6pl Not registered yet? Secure your spot now! ow.ly/JYQl50Zz6pr #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD

CRF is deeply saddened by the passing of Professor Jo Dens. A widely respected interventional cardiologist, educator, and mentor, he was a beloved figure in the European CTO community who trained and inspired countless physicians throughout his career. Remembered for his expertise, generosity, and remarkable spirit, Professor Dens leaves an enduring legacy that will continue to shape cardiovascular care for years to come. Our heartfelt condolences go out to his family, friends, and colleagues.

Don’t miss this final opportunity to share research that can shape the future of interventional cardiology!

In calcified nodules morphology influences hemodynamics 🌊 Eruptive calcified nodules generate significantly higher velocities and greater shear stress heterogeneity than non-eruptive nodules. This may lead to higher platelet activation in eruptive nodules Great collaboration @PoliTOnews and @crfheart

Practice at the highest level with world-class education and training at #TCT2026! 🌴 From groundbreaking clinical science and innovations that transform care to live cases and dynamic training that help you master advanced techniques, TCT is where the future comes to life. ✨ 🔗 ow.ly/Wgeu50ZvYkh #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD

What began as an idea #CTguidedPCI is becoming an increasingly accessible platform for interventional cardiologists. Today, at least four companies—@HeartFlow, @Cleerly, @ElucidBio, and @SiemensHealth —have developed dedicated #CCTA platforms for the interventional cardiologist 👇 Now the field is waiting for the pivotal #P4 trial, to be presented at @TCTMD. The next chapter of PCI planning is about to begin 💪 #CTguidedPCI #Cardiology #TCT2026 @crfheart @PCRonline

It is remarkable how quickly photon-counting CT #PCCT is transforming clinical practice. We now use CT to characterize coronary calcium before #PCI, enabling more precise lesion preparation. I believe PCCT will become the standard for coronary CT within the next five years.

Make this the year your science takes center stage. 💥 Submit your breakthrough research to #TCT2026 and share it with the global #interventionalcardiology community. 📅 Deadline: August 7 | 2:00 PM EDT 👉 ow.ly/OR5i50Zt0Ng Every submission counts! Each one helps boost your institution’s standing in the TCT 2026 SET-10 Rankings.🏅 #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD

Sublingual NTG induced a significant decrease in left ventricular preload and afterload, resulting in a marked decrease in myocardial work. This was associated with a significant and adaptive decrease in absolute coronary blood flow. jacc.org/doi/10.1016/j.jcin.… #JACCINT #cvCAD

Residual angina after PCI is common. The explanation depends on the interaction between microvascular dysfunction and the epicardial disease pattern 🎯 Focal CAD: successful PCI unmasks coexisting CMD. 〰️ Diffuse CAD: persistent epicardial resistance remains the dominant cause. Impact of Coronary Microvascular Dysfunction on Patient-Reported Symptoms After PCI | jacc.org/doi/10.1016/j.jacad… @crfheart @PCRonline @AbbottNews @bouissetfred #PCI #CoronaryPhysiology #CMD #PPG

I’ve learned so much from Sho and Gaku about the pathology and progression of coronary calcification. This paper is a major contribution and an important step toward advancing our understanding of calcified coronary disease @crfheart