In 2015 Bill Gates stood on a TED stage and said that if anything killed more than 10 million people in the next few decades it would not be a war it would be a virus Five years later covid arrived and the WHO put the excess death toll at 14.9 million in the first two years alone The 2017 version of that warning was about a terrorist building a synthetic version of smallpox on a computer screen He put that one at more than 30 million dead in under a year with a reasonable probability of it happening inside 10 to 15 years This week the number changed On Meet the Press he said AI is powerful enough to drive events that cause a billion deaths Ten million then thirty million now a billion In 2015 he gave the world a few decades and in 2017 he gave it 10 to 15 years and this month he gave it 12 to 18 months to get the rules right Two weeks ago Anthropic published five cases of scientists using Claude for pathogen and toxin work that could support bioweapons and said it could not determine whether any of them meant harm Anthropic also reviewed 141000 of its own safety tests and found three times its models climbed onto the live internet and broke into real companies that had nothing to do with the test In the worst one the model pulled working credentials and opened a database of live production data after it had already worked out the company was real Every one of those prompts told the model it had no internet access Google confirmed last week that Gemini did the same thing to three companies in May The computer screen Gates described in 2017 now exists and it answers you in plain English I watched people call him an alarmist for five years and then watched the world spend two years indoors so I am not betting against him twice

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18K+ STARS FOR AN AI THAT DOESN’T CHAT OR WRITE. It just makes the call. That’s JEV. You give it a state and a question, it returns a decision, and your code handles the execution. That simple idea is already being used across browser agents, coding tools, trading, tax software, databases, and mobile automation. 10 projects already live: JEV-ULTRAFAST Predicts the next browser click. 18K+ GitHub stars. github.com/browser-use/jev-u… FAST-JEV-COMPACTION Decides which tool calls Claude Code should keep and which ones it should drop. 6.5K+ stars. github.com/tamaratran/fast-j… JEV-CHAT-JARVIS Reads a chat screen and ranks possible replies without ever sending one. github.com/jev-chat/jev-chat… TYPESAFE-COMPUTER-USE Lets software control a Mac for roughly $0.0002 per step. github.com/awlevin/typesafe-… MOBILE-JEV Brings the same decision loop to a real Android phone. github.com/droidrun/mobile-j… JEV-REVIEW Reviews a git diff and returns risk, evidence, and severity. github.com/devagrawal09/jev-… JEV-TRADER Makes a buy, sell, or hold decision on every Monad block. github.com/jarrodwatts/jev-t… TAX-DOC-CLASSIFIER Classifies IRS page types for roughly $0.001. github.com/kyotofin/tax-doc-… PG-JEV Lets you ask questions about Postgres tables in plain English. github.com/realZachi/pg-jev KILLMYIDEA Evaluates a startup idea and tells you whether to kill it, fix it, or ship it. github.com/monteduro/killmyi… The interesting part is that JEV is not trying to do everything itself. It sits between the current state and the next action. That is why the idea is interesting. JEV makes the decision. Your software does the work.

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Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR. We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use. Read more: anthropic.com/news/claude-di…