An extraordinary @Nature paper has just landed from the lab of @Sergiu_P_Pasca at @Stanford - led by Konstantin Kaganovsky. They have found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells. This human-derived cortical graft integrates deeply with the host nervous system, supporting organised neural activity and behaviour. This study is a milestone in synthetic biology and chimera research. It has the potential to generate multiple medical breakthroughs by providing an enhanced biological model of human brain tissue that allows behavioural as well as neural and genetic assays. The Stanford team have been exceptionally thorough and proactive in addressing ethical concerns that comes from this frontier work. But their pioneering work nonetheless raises many open questions: are the xenocortical mice conscious? Do they have any human-like properties of consciousness or cognition? @NitaFarahany and I will be addressing some of these questions in a forthcoming commentary - where we'll also offer an ethically-informed roadmap to guide this important research as it progresses. In this context, "pacing the frontier" really does make sense 😉 Read the Stanford @nature paper here, and buckle up. It's wild. nature.com/articles/s41586-0…

요즘 이 영상 ㅈㄴ중독되서 계속 보는 중

8月中旬 币安官方公布了自己的AgentOS，与此同时举办了黑客松比赛，并将AgentOS放到了币安官网中与买卖代币，广场社交在视觉交互的同一个地方，可见币安对于Agent OS的重视程度 所以我在想 能否打造一个既懂web3市场 又有自己独特的思考 又能自己参与链上meme和股票交易的agent 于是 $BAOS （Binance Agent OS）诞生了，为了让她懂市场，所以技术底座完全是基于 Binance Agent OS，相当于整个agent的大脑；为了让她有自己独特的思考，我们引入JEV让AI每次在决策判断前能够精准快速；为了让它能够参与链上股票和meme交易，我们加入了币安自己的402技术，让他在bsc链的每一笔交易都可信且可查 $BAOS 从立项到实现花了我五天四晚时间，熬了无数个通宵，改了20多次版本迭代，为了给 $BAOS 设计多个角色 并单独为每个角色设定了属于她自己独特的动作、语言、思维和动画，为此榨干了三个Codex账号额度以及封停了两个Claude账号，就是为了认真做好这个BAOS BAOS 没有抄袭或借鉴任何已有的产品，而是我们基于市场和产品的思考而创造的，她的诞生目的只有三个：让链上的每一个bsc链用户都能体验到 Biance Agent OS带来的技术革新，让agent能够和P小将一样能够参与链上竞争并赚取财富养活自己，赋予Agent灵魂 能够让她和人一样独立思考并依靠达强大的大模型能力快速精准捕捉到关键信息并为用户提供实时快速的数据分析 在AI发展到今天，我们每个人都是见证者，也是实实在在的体验者，从最开始AI只能陪你聊天，到现在能真正帮你解决各种操作系统 软件 网页上的高难度复杂工作。 我们真的应该用发展的眼光去看待Agent的迭代更新，而 $BAOS一定会是BSC链 Agent的先驱！ 未来已来

I’m this old when memes were just JPEGs.

An extraordinary @Nature paper has just landed from the lab of @Sergiu_P_Pasca at @Stanford - led by Konstantin Kaganovsky. They have found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells. This human-derived cortical graft integrates deeply with the host nervous system, supporting organised neural activity and behaviour. This study is a milestone in synthetic biology and chimera research. It has the potential to generate multiple medical breakthroughs by providing an enhanced biological model of human brain tissue that allows behavioural as well as neural and genetic assays. The Stanford team have been exceptionally thorough and proactive in addressing ethical concerns that comes from this frontier work. But their pioneering work nonetheless raises many open questions: are the xenocortical mice conscious? Do they have any human-like properties of consciousness or cognition? @NitaFarahany and I will be addressing some of these questions in a forthcoming commentary - where we'll also offer an ethically-informed roadmap to guide this important research as it progresses. In this context, "pacing the frontier" really does make sense 😉 Read the Stanford @nature paper here, and buckle up. It's wild. nature.com/articles/s41586-0…

An extraordinary @Nature paper has just landed from the lab of @Sergiu_P_Pasca at @Stanford - led by Konstantin Kaganovsky. They have found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells. This human-derived cortical graft integrates deeply with the host nervous system, supporting organised neural activity and behaviour. This study is a milestone in synthetic biology and chimera research. It has the potential to generate multiple medical breakthroughs by providing an enhanced biological model of human brain tissue that allows behavioural as well as neural and genetic assays. The Stanford team have been exceptionally thorough and proactive in addressing ethical concerns that comes from this frontier work. But their pioneering work nonetheless raises many open questions: are the xenocortical mice conscious? Do they have any human-like properties of consciousness or cognition? @NitaFarahany and I will be addressing some of these questions in a forthcoming commentary - where we'll also offer an ethically-informed roadmap to guide this important research as it progresses. In this context, "pacing the frontier" really does make sense 😉 Read the Stanford @nature paper here, and buckle up. It's wild. nature.com/articles/s41586-0…

@Sergiu_P_Pasca who is the Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program, a CZ BioHub Investigator and a science fellow of the Hoover Institution at Stanford Stanford researchers transplanted human cortical organoids into mice lacking most of their cortex. Within three months, over 90% of the animals’ cortical tissue by volume was human-derived—and rare von Economo neurons appeared, something organoids in a dish had never produced. To me, the real breakthrough is not that scientists “grew a human brain in a mouse.” It is that human neurons can now develop inside a living system with blood supply, sensory input and motor output. This could transform research into cerebral palsy, epilepsy, autism and schizophrenia. But as these models become more biologically realistic, ethical oversight must evolve just as quickly. Science should not stop because the questions are difficult—but ethics cannot be added only after the technology matures. med.stanford.edu/news/all-ne… 0xec5b95a544f98430f6b0cfc3d6dd82b61a417777 #Neuroscience #BrainOrganoids #Biotech

“Part-human part-mouse brain developed in science breakthrough”

一看就知道是金狗了

市场上全是 AI 套壳“神经果蝇”，用大模型随机编一个交易答案就敢叫自己果蝇大脑。 只有 FlyNeuron 真正用了 Janelia 电子显微镜重建的 MaleCNS v1.0 论文数据：16.67 万个真实神经元 + 2560 万条真实突触，跑在 LIF 脉冲网络里，把 BSC 行情变成视觉威胁和食物气味，再让果蝇自己的神经回路做出 EAT / FLY / SLEEP 决策。 不是模仿，是把论文里的连接组直接搬上链。 The market is full of AI-wrapped “neural fruit flies” — just LLMs making up random trading decisions and calling themselves a fruit fly brain. FlyNeuron is different. We use MaleCNS v1.0, reconstructed from Janelia’s electron microscopy data: 166,700 real reconstructed neurons + 25.6 million real reconstructed synaptic connections The connectome runs as a LIF spiking neural network. BSC market conditions are encoded into simulated sensory inputs — such as visual threats and food odors — and fed into the fly’s neural circuitry, which produces EAT / FLY / SLEEP decisions. This isn’t an AI pretending to be a fruit fly. We took the connectome from the research data and brought it on-chain.

没错，所以我们找到了 Flap。 我们向 Flap 申请了一台专用服务器，把整套 MaleCNS 果蝇大脑放了进去。 166,700 个神经元，25,582,938 条连接，都在这台服务器上实际跑。 不是一张图，也不是让 AI 假装成一只果蝇。 现在这只果蝇的“大脑”，就在 Flap 的服务器里。 这才是真正的“永生果蝇”

Every dip is an opportunity.