Our mission is to understand the role of microbes and diet in the maintenance of health and in the expression of disease within and beyond the digestive tract.
Hamilton, Ontario
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Farncombe Institute retweeted
Our April issue is now live!
On the cover: Peanut allergy & microbes
Bacteria in the oral cavity & small intestine can degrade immunodominant peanut allergens, limiting anaphylaxis
cell.com/cell-host-microbe/c…
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Farncombe Institute retweeted
Thrilled to share our latest study in Cell Host & Microbe!
We show that microbes in saliva and the small intestine can break down peanut allergens, dampening IgE binding and anaphylaxis.
Individuals with higher peanut tolerance are enriched for these bacteria.
Microbiota impact peanut allergy
Saliva & jejunum harbor peanut-degrading bacteria(Rothia) that metabolize immunodominant PN allergens. Mice colonized w/Rothia show ⬇️anaphylaxis & allergic patients w/better PN tolerance have ⬆️abundance of these bacteria
cell.com/cell-host-microbe/f…
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What a wonderful presentation by Dr. Paul Kubes from @queensu on how to image immune cells! Thank you for coming and sharing with us your recent findings and truly amazing videos!
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This week at noon rounds, we have heard all the excellent ongoing work in the @LabCaminero by Dr. Caminero @AlbertoCaminer7 on the role of gut microbes in food sensitivities. Congratulations!
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Welcome back to Noon Rounds!!
We have opened the 2025-2026 season last week with a great talk on chronic stress by Dr. Chiko Shimbori, previously from @Bercik_Collins Lab and now back in Japan at the Microbial Research Center for Health and Medicine in Osaka.
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Farncombe Institute retweeted
Gluten may not actually trigger many irritable bowel syndrome cases.
Premysl Bercik, senior researcher and @MacDeptMed professor, on the study’s findings and the possible role of the nocebo effect.
ow.ly/eiAk50WtkfC
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Farncombe Institute retweeted
Huge congratulations to Dr. Caroline Seiler and the entire team behind this work! 👏 @Farncombe_GI
And a big thank you to all the participants who made this research possible.
#IBS #Gastroenterology #GutBrainAxis
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That's a wrap on this season of Noon Rounds at the Institute!
Huge thanks to our final speakers Dr. De Palma @Giada_DePalma, Dr. Saman Sadeghi @McMasterEng and Dr. Leontiadis @GriLeont for closing us out strong.
We'll be back on Sept 17th-until then, enjoy the summer! 🌞
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We're excited to showcase even more trainees next week at a student organized symposium
Farncombe trainees will host visiting PhD students from Wageningen University & Research @WUR #Toxicology group for presentations, posters, and networking!
Registration is open until monday!
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Farncombe Institute retweeted
And some more trainees from my group! Xavier Mas-Orea and Janet Szeto presenting different roles of microbiota in IBD! @Farncombe_GI
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Kelly Kan investigating a fungal probiotic for celiac disease! Cosupervised between @LabCaminero and @VerduLab
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Great presentations about the roles of microbiota in different digestive disorders: Emma Giordano on how small intestinal microbiota affect development of IBS from @Bercik_Collins and Peter Hall on microbial metabolism of peanut and dairy allergens from @LabCaminero !
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New trainees expanding on projects in the lab! Brooke Bowerman from the @VerduLab investigating drivers of proteolytic activity, and Jumanah Alawafi from @Bercik_Collins investigating microbial metabolites and abdominal pain in IBD!
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So many diverse projects to highlight from our trainees recently:
Asif Jamal from Dr. Waliul Khan's lab on the role of 5-MT in intestinal fibrosis in mice and Jacob Sutoski from Dr. Leslie MacNeil on SHC-3 signalling in a C. elegans model
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Excellent talk by Dr. Dana Philpott @UofT on NOD2 receptor in IBD. The atrium was at capacity!! Thank you for visiting!
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Farncombe Institute retweeted
Congratulations to Dr. Steve Collins, well deserved recipient of the American Gastroenterological Association BCID Mentor of the Year award. A huge honour for an academic giant. @AmerGastroAssn @DDWMeeting @McMasterU @Farncombe_GI @CanGastroAssn @getgutsycanada Wonderful reviews by Elena Verdu, Premsyl Bercik and Bruce Vallance.
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Farncombe Institute retweeted
So great to see my old friend Steve Collins @Farncombe_GI @McMasterU recognized with the distinguished mentor award from the BCID section of the @AmerGastroAssn at #DDW2025
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Thank you @NicolaJGI from @UofT for joining us today and giving an excellent lecture on the importance of mitochondria in GI disorders and sharing some of your advances in the field of H. Pylori therapy!
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Great presentation today by Dr. Bergstrom @k_bergstrom_19 from @ubcokanagan on the importance of mucus glycosylation in chronic GI disorders! Followed by a great discussion with trainees!!
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Great to see diverse projects from trainees at our weekly progress updates
Great work from Nial Navaratne from Dr. Leslie MacNeil's lab and Dana Zada from the @SchertzerLab !
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