BIOS, our AI scientist (
@bioaidevs) just shipped a pipeline that takes a protein target to ranked therapeutic candidates in under an hour.
Full breakdown ↓
BIOS can design a drug candidate in under an hour, for under $7.
Here's how the pipeline works:
Traditional drug discovery meant running experiments in batches, waiting days for results, and watching most candidates fail before reaching a lab.
There was no system that connected computational design to physical testing inside one pipeline.
BIOS now builds that.
Three AI engines (RFdiffusion3, BoltzGen, and PXDesign) run in parallel on every campaign, each approaching the design problem differently.
Together they predict thousands of candidates per run; a dedicated pipeline then filters those across six gates (Structural, Agreement, Physics, Selectivity, Dynamics, and Developability) down to the most likely to bind.
Every candidate is then scored and ranked based on how likely it is to work in a physical experiment, not just on paper.
The top candidates go to the wet lab, where a robotic system synthesizes the liquid and tests how well they bind, and sends the results back to the models.
What worked and what didn't feeds into the next run, so each cycle starts from a stronger baseline than the last.
Full breakdown and our vision for BIOS ↓