Final Version of our article on UBR-box E3 ubiquitin ligases, protein synthesis and skeletal muscle size now online 🚨 | @AJPCellPhys @CraigAGoodman1 @DrAdamPSharples | journals.physiology.org/doi/… Review in this area recently published here: journals.lww.com/acsm-essr/f… #Myotwitter

A scorched-earth approach to aging research by Rich Miller 🔥 Pretty much everything gets criticised, from the hallmarks of aging to cell senescence, epigenetic clocks, and cellular rejuvenation. But Rich makes some very good points. I particularly like the Rolex analogy regarding aging clocks. If you’re working in aging science, please read it and thank me later! It's an entertaining and much-needed critical perspective. For the record, I was a reviewer of this paper, and suggested a little more nuance and balance. My suggestions didn't make it to the final version, though. Why be balanced when you can just burn everything in your path! 🔥 link.springer.com/article/10…

A discovery from Dr. Ken Humphries' lab points the way toward a potential therapeutic target for diabetic heart disease, a condition that affects millions of Americans. 🫀 Read more: omrf.org/omrf-lab-discovers-…

An integrative multi-omic analysis of skeletal muscle in response to disuse and recovery resistance training in resistance trained and untrained young adults link.springer.com/article/10…

Policy decisions shape what physiology research can achieve. Our new guide explains how the U.S. research system works, why it matters, what is at risk and the policies to know: ow.ly/eQWL5101vgE #SciPol #Advocacy

Adipocyte Lipolysis is a Determinant of Skeletal Muscle Size During Fasting and Feeding journals.physiology.org/doi/…

As someone studying exercise-induced epigenetic memory, my first thought was: "we call this exercise". Mechanical loading deforms muscle fibres and nuclei. Do loading and unloading leave lasting mechano-epigenetic signatures that shape adaptive capacity with ageing?

The measurement, training and function of glycolysis is much less researched than mitochondrial biogenesis. Next week Kenneth M. Humphries will give the 26th HyperMet DFG Research Group talk on PFKFB2. Join here: teams.microsoft.com/meet/354…

Ets2 Is an Activity-Dependent Transcriptional Regulator of a Fast-Twitch Muscle Program faseb.onlinelibrary.wiley.co…

Looking for a postdoc interested in ageing biology and proteostasis 📅 Deadline: Nov 15 More details in attached document #Postdoc #PostdocOpportunity #Proteostasis #LongevityResearch #AcademicJobs #ResearchJobs

New @NatMetabolism paper: Systemic proteomic dynamics of acute exercise reveal genetic links to health and disease. tinyurl.com/bdh8rrbj

Congratulations to the CMR's @CaldowMarissa, @GordonSLynch and Team for their new paper, "Tomatidine Exposure During Early Myogenesis Promotes Hypertrophy of C2C12 Muscle Cells Through Increased Nuclei Accretion" @CellAgAustralia #myotwitter onlinelibrary.wiley.com/doi/…

I have it pretty easy thanks to my brilliant wife, and I’ve got into work patterns that protect our family time. Yet, I’m also often wondering how we can make academia better for all aspects of what life can give us.

Ready to go ✅💪🏼 #myotwitter

Applications for our 2027 summer scholars are now open! ⭐🧬🔬 We’re looking for motivated, curious students to spend their summer at OMRF. During this 8-week, paid research experience, scholars work on individual projects in cutting-edge labs, guided by OMRF scientists.

An integrative multi-omic analysis of skeletal muscle in response to disuse and recovery resistance training in resistance trained and untrained young adults link.springer.com/article/10…

Spatial Transcriptomics Identifies Muscle Inflammation Susceptibility as a Distinct Periarticular Skeletal Muscle Phenotype in End-Stage Knee Osteoarthritis biorxiv.org/content/10.64898…

Our latest @MolMetab - a Clock/Ampk connection! The Circadian Clock Component NPAS2 is modulated by AMPK and Regulates Substrate Utilization and Mitochondrial Function in Human Skeletal Muscle. Great collaboration w/team @karolinskainst @Metabolcenter sciencedirect.com/science/ar…

LATEST FREE PAPER : 60 g/h of CHO spares muscle but not liver glycogen using during HIT training. Congrats Sophie Hannon on latest PhD publication and all-co-authors on a great collaboration @Hearris journals.physiology.org/doi/…

Thanks to this Legacy Grant from @OklahomaTSET, we will be able to continue helping patients and Oklahomans across the state! Watch more from our groundbreaking in May: youtube.com/watch?v=NoKIThf5…

Interactions Between E3 Ubiquitin Ligases and Deubiquitinases in AKT Regulation: Implications in Skeletal Muscle Homeostasis | Review pubmed.ncbi.nlm.nih.gov/4267…