Exclusive news, features, and analysis on the research, tools, regulations, and applications driving precision medicine. From the publisher of @GENBio
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🎧 Behind the Breakthroughs
Step into the minds shaping the future of medicine.
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#PrecisionMedicine #BehindTheBreakthroughs #MedTech #Biotech
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Riaan's Therapeutic Odyssey – Chapter 4: The Drug Developers
Transforming one-off therapies into accessible and repeatable programs requires early strategy and shared infrastructure
@GrinsteinJ #AurelixBio
#genetherapy #drugdevelopment #rarediseases
hubs.li/Q04ykw7L0
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Detecting Ovarian Cancer Earlier with New MIT Tissue Sampling Device
The device allows for the collection of living cells that are removed from the area using shear force, which gently detaches the cells
@MIT
#ovariancancer #tissuesamples #cancerscreening
hubs.li/Q04yklFx0
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Just a Flesh Wound: The Combative Quest for Cancer's Holy Grail
Experts debate the evidence, uncertainties, and readiness for widespread use of GRAIL’s Galleri multicancer early detection test (MCED)
@GrinsteinJ
#cancerscreening #oncology #bloodtest
hubs.li/Q04ykhQG0
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Off Script: Why Some CAR T Patients Develop Enterocolitis—and How to Treat It
Researchers discovered why some #CARTtherapy patients develop severe intestinal inflammation and a repurposed oral inhibitor to treat it
@MountSinaiNYC
#colitis #antibodies
hubs.ly/Q04yd29r0
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Gut Microbiome Development Pattern Linked to Type 1 Diabetes Risk
Early plateauing of gut microbiome development was linked to threefold higher type 1 diabetes risk
@BrighamWomens @harvardmed
#diabetes #GImicrobiome #immuneresponse
hubs.ly/Q04yd1wb0
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Wei-Wu He: Craig Venter’s Legacy and the Future of Human Longevity
@humanlongevity's executive chairman @HeWei16027 discusses Craig Venter's vision of using #genomics and AI to extend healthy life and dramatically reduce serious illness
#lifespan #podcast
hubs.li/Q04y78KB0
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Beacon Therapeutics’ Eye Gene Therapy Succeeds in Late Stage Trial
@BeaconTx_ reports positive results in its Phase II/III trial of its gene therapy for treatment of X-linked #retinitispigmentosa
@LanceBaldoMD
#genetherapy #clinicaltrial #AAV
hubs.li/Q04y76yZ0
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Mark Your Calendar! Highly Multiplexed Droplet Digital PCR for Ultra-Sensitive NSCLC Biomarker Detection in Research Workflows
Register for this free webinar sponsored by Bio-Rad: hubs.ly/Q04xHPDk0
#CancerBiomarker #NonSmallCellLungCancer
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Could RNA Therapy Preserve Lean Muscle and Boost Fat Loss During GLP-1 Treatment?
A @NorthwesternU-developed #RNAtherapy helped preserve lean mass and increase fat loss when combined with #semaglutide in mice, pointing to a potential new #obesity strategy
hubs.li/Q04y1L2r0
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Exposure to ‘Forever Chemical’ Hampers Body’s Ability to Fight Viruses
Exposure to the forever chemical PFOS makes it harder for the body to fight off viruses, according to a study in mice and human cells
@CAS__Science
#PFAS #viraldiseases #hepatitisB
hubs.li/Q04y1JNX0
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Paper Battery Prototype Could Power Devices Inside the Body for Days
An ingestible paper battery that lasts for several days and breaks down without notable toxicity was successfully tested in pigs
@MIT
#biodegradation #medicaldevices #animalmodels
hubs.li/Q04xZ0bG0
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CRISPR Activation Tool Uncovers Genes Linked to Lymphoma Drug Resistance
A new CRISPR screening platform has identified a gene causing lymphoma cells to become resistant to venetoclax
@MarcoHerold_J @ONJCRI @latrobe
#CRISPR #lymphoma #resistancemutation
hubs.li/Q04xYdxD0
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IASLC Tumor Budding Grade Identifies High-Risk Lung Squamous Cell Carcinoma Patients
High-grade tumor budding was associated with significantly increased risks for death and recurrence in resected #lungsquamouscellcarcinoma
#YonseiUniversity #chemotherapy
hubs.li/Q04xHT0c0
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Giant-Nucleus Cells Linked to Early-Stage Cancer and Ferroptosis Resistance
In a study of #kidneycancer in rats, a Japanese team found that giant-nucleus cells that survive iron-induced damage may form the foundation of #earlystagecancer
@NagoyaUniv
hubs.ly/Q04xHRgw0
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Collagen-Targeted MRI Contrast Agent Improves Detection of Small Lung Tumors and Metastases
A novel collagen-targeted MRI contrast agent detects #lungcancer and metastases with greater sensitivity in preclinical models
@GeorgiaStateU
#metastasis #MRI
hubs.ly/Q04xHQMr0
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Liquid Biopsy Shows Potential to Detect Pancreatic Cancer Before It Turns Invasive
PANXEON combines microRNA #biomarkers with CA19-9 to detect early #pancreaticcancer and potentially identify high-risk lesions before they become invasive
@cityofhope
hubs.ly/Q04xHQc-0
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Thermo–Mayo Clinic Collab to Detect Disease Prior to Symptom Formation
Precure, LLC, is the newly launched collaborative that integrates #multiomics and clinical data to identify early signs of disease
@MayoClinic @thermofisher
#AI #earlydiagnosis
hubs.li/Q04xRNdC0
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Tracking Blood Test Results Over Time Could Support Earlier Cancer Detection
Routine #bloodtests may reveal hidden warning signs of cancer in patients with non-specific symptoms such as unexplained weight loss
@PradeepVirdee @UniofOxford
#cancers
hubs.li/Q04xRMz20
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Anti-Seizure Drug Could Slow Aggressive Childhood Brain Tumors
An existing anti-seizure medication may offer a way to fight diffuse midline glioma, one of the deadliest forms of childhood #braincancer
@michelle_monje @StanfordMed
#cancerimmunotherapy
hubs.li/Q04xK-lW0
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Smart Contact Lens Monitors Stress
The “lab-on-a-contact lens” offers a way to repeatedly and noninvasively measure a key #stress hormone and demonstrates the value of #wearablediagnostics for personalized, remote health monitoring
@TerasakiInst
#hormones
hubs.li/Q04xLfTB0
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