Jonathan S. Weissman's lab at the @WhiteheadInst/@MIT. Account run by lab members.
Cambridge, MA
- Tweets 182
- Following 3,514
- Followers 11,216
- Likes 341
We’re hiring a Technical Assistant I/II in the Weissman Lab @WhiteheadInst to work on in vivo functional genomics with multimodal readouts.
Our technicians have had incredible success going on to PhD & MD/PhD programs. Apply or send great candidates our way!
1
7
25
4,370
Excited to share our new preprint led by
@YiChenNeumann with incredible collaborators @labs_mann, @BenGewurz, @StephenE92884, and @hopfnerlab
to characterize the function of thousands of viral microproteins from human-infecting viruses! biorxiv.org/content/10.64898…
Excited to share my PhD work, now on @bioRxiv! 🎓🦠Viruses are packed with small ORFs with unknown function. At @JswLab w/ collaborators, we built a pan-viral microprotein atlas that uncovered the oncogenic activity of BNLF2b, an EBV gene linked to cancer.
biorxiv.org/content/10.64898…
2
25
116
15,326
Jonathan Weissman's Lab retweeted
Excited to share my PhD work, now on @bioRxiv! 🎓🦠Viruses are packed with small ORFs with unknown function. At @JswLab w/ collaborators, we built a pan-viral microprotein atlas that uncovered the oncogenic activity of BNLF2b, an EBV gene linked to cancer.
biorxiv.org/content/10.64898…
6
32
93
21,450
Impressive work from @JShendure & co. reconstructing an E13.5 lineage tree with DNA Typewriter. A great complement to our PEtracer lineage atlas spanning E7.5-E10.0 (mela.wi.mit.edu). Excited to see what an integrated analysis of these datasets reveals!
Thrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote
1/n
1
8
76
11,158
Exciting work led by @AniaPuszynska !
Excited to see our work now published science.org/doi/10.1126/scie…!
Lysosomal dysfunction has long been considered a hallmark of aging, but we still know remarkably little about what actually changes inside lysosomes as organisms grow old. Using rapid lysosome isolation and metabolomics, we built the first atlas of lysosomal aging across tissues.
5
23
5,807
Jonathan Weissman's Lab retweeted
📣 new preprint multimodal atlas. Imaging + scRNA, 57M cells. 🧬🔬
Cells are complex dynamical systems — but most ways we measure them destroy them. We asked: how does live imaging compare to scRNA-seq, the field’s gold std?
The answer surprised us 🧵
biorxiv.org/content/10.64898…
5
65
276
30,975
Jonathan Weissman's Lab retweeted
What is the global structure of cell-state space—and how do perturbations drive transitions within it?
Excited to share our new preprint (biorxiv.org/content/10.64898…), a work in collaboration with @JswLab.
1
74
314
21,998
Jonathan Weissman's Lab retweeted
A few years in the making in the @JswLab with @WilliamNColgan, Zack Smith, and the rest of our fantastic team: Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis. Excited to hear everyone's thoughts!
Excited to share a new preprint from the lab led by @LukeKoblan and @WilliamNColgan in which we describe our efforts to define a quantitative cell fate map of mouse embryogenesis! biorxiv.org/content/10.64898…
2
2
27
4,220
Excited to share a new preprint from the lab led by @LukeKoblan and @WilliamNColgan in which we describe our efforts to define a quantitative cell fate map of mouse embryogenesis! biorxiv.org/content/10.64898…
4
58
233
64,416
This has been a wonderful collaboration between our group and Zachary Smith’s Group @yalemed and the Max Planck Institute with important contributions from @nir_yosef1 @WeizmannScience, @ZhuangLab @HarvardCCB, and Kyle Loh @Stanford
1
4
1,196