For an innovative piece of materials science and electrical engineering, take a look at our most recent paper in the area of bioelectronics, published today in the current issue of Nature Electronics – “A Wirelessly Powered, Light-Controlled, Bioresorbable Stimulation System With Programmable Polyphasic Waveforms.”
nature.com/articles/s41928-0…. Here, we introduce a scheme in which light illumination serves as a mechanism for precisely shaping the temporal and spatial profiles of electrical stimulation delivered to targeted tissues by a battery-free, flexible implant. The work includes not only detailed studies of all of the aspects in engineering science but also elaborate examples in advanced forms of control of cardiac rhythms and respiratory patterns, via cardiac pacing and phrenic nerve stimulation, respectively. The key to device operation is in the combined use of small-scale coils for radio frequency power transfer and miniaturized bipolar junction transistors for optical modulation – all constructed in materials that support high-performance operation but are uniquely defined by their ability to dissolve naturally and harmlessly inside the body following stable operation over a clinically relevant timeframe for treatment of temporary patient conditions. The paper is the result, primarily, of the efforts of a remarkably talented pair of former postdoctoral fellows in the group – Prof. Jong Uk Kim (now on the faculty at
@SKKUni1398) and Prof. Seung Gi Seo (now on the faculty at Kumoh National Institute of Technology) – also with essential contributions from Dr. Hongkai Wang and Dr. Eric Rytkin in medically relevant demonstrations. Of course, the various roles of the many other co-authors were also very important. Key senior investigators include Prof.
@IEfimov (cardiac), Prof.
@ColinFranzMDphd (phrenic), Prof. Sung Hun Jin (BJT processing) and Prof. ZHENQIANG MA (BJT physics). Thanks to everyone for the great collaboration! Also, thanks to Prof.
@JunChenLab for writing a nice News and Views perspectives piece on our work, published alongside our paper in this issue of Nature Electronics!
nature.com/articles/s41928-0…