Studying sleep & brain development. Mostly in flies. Physician Scientist Psychiatrist. Training Director, Penn Psychiatry Residency Research Track.
Philadelphia, PA
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Newest preprint & we think it's a big one! Young animals sleep a ton, but not with a daily pattern. What controls emergence of circadian sleep🌘? In flies we figured out WHEN and HOW. But WHY?? Sleep rhythms enable ability to make enduring memories🤯🤯 biorxiv.org/content/10.1101/…
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ft. Kyla Mace, @atothezphd, Fusun Doldur-Balli, Erika Almeraya Del Valle, Allan Pack, @KayserLab (@pennsleep), @AlessandraChesi (@PennPathLabMed), Hayle Kim, Jeffrey Rosa, (@PennPsych) & Struan Grant (@ChildrensPhila) @NatureComms nature.com/articles/s41467-0…
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I need people to understand how difficult it is to get an NIH grant. You spend months writing a proposal, following strict guidelines that include a detailed multiyear budget, bios of everyone on your team, plans for participant safety & ethical conduct. Then you send it off -1/n
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Sleep is complex, & so was this study. Congrats to Adil @SleepSeq for finishing this project to link neural stem cells to sleep behavior. This was only possible with sleep experts @Budha, Jenny, @KayserLab & $$$ from multiple sources. Congrats all! doi.org/10.1016/j.cub.2024.0…
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Rising star @ZPRosenthal PGY-3 Resident @PennPsych uses a novel mouse model of electroconvulsive therapy (ECT) and DCS/FD-DOS in humans to show that: ECT generates a hidden wave - CSD - after seizure biorxiv.org/content/10.1101/…
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Check out our latest! Going from human🤷♂️to fly🪰to fish 🐟 as we try to figure out what makes some people excessively sleepy during the day - idiopathic hypersomnia💤
biorxiv.org/content/10.1101/…
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These cross-species approaches use human genomics to fly mechanism to point to new therapies in a vertebrate model. Now funded by @NIH_NINDS
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Fantastic collaboration with @STRUANGRANT @AlessandraChesi @atothezphd and Allan Pack among many others. More to come!!!
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I’m hiring a research technician! Recent college grads or anyone graduating in December should apply. Please RT!! uasys.wd5.myworkdayjobs.com/…
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Congratulations on a masterful thesis defense by DR. KYLA MACE!!! An amazing scientist and even more amazing person. We are bursting with pride over here y’all 🥳🤩
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🐣 July's most-read Developmental Biology paper shows how early life eating shapes the development of the sleep/wake cycle in fruit flies: elifesciences.org/articles/9…
Have a paper people should see? See what our Editors look for: elifesciences.org/about/aims…
ALT red eyed fruit fly feeding
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The Poe lab officially opened today!!! It still hasn’t been cleaned out yet but the doors are open 🥳
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do you love philly? are you a brilliant, up-and-coming scholar in neuroscience? apply to be a SPINE fellow! fellows will journey to philly, present their work at a symposium, and meet with local faculty. the deadline is july 26th, so apply now and reach out with questions!
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Check out our latest @eLife! We discover how changes to energetic demand across development govern the emergence of daily sleep patterns. Congrats to departing postdoc Amy Poe who led the work, heading to start her own lab @UArkansas in 2 weeks!!!
elifesciences.org/articles/9…
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🔥🔥CALLING NEURO POSTDOCS🔥🔥don’t miss an opportunity to apply for this great symposium and learn about opportunities @Penn and other institutions across Philadelphia!!
🔬 Attention neuro postdocs!! Apply now for a great opportunity to present your research at the SPINE symposium @SPINEPhilly @Penn.🧠 #Neuroscience
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