Izhak Kehat's Molecular Cardiovascular System Research Lab @TechnionLive

Israel
Kehat Lab retweeted
@CircRes Aug 28th Issue is Out! ahajrnls.org/3wPOBJJ Cover: Cardiac MMA accumulation drives mitochondrial dyshomeostasis & damage under diabetes (arrow). Localized toxic onslaught (shield) is refractory to blood glucose control & traditional cobalamin supplementation.
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Kehat Lab retweeted
Induced Lox KO in Myh11+ Smooth Muscle Cell, but not PDGFRฮฑ+ fibroblast, โฌAngiotensin II-induced ๐ŸญCardiac Fibrosis Cardiac hypertrophy remains unaltered in both Lox KO models A possible SMC-to-Fibroblast matrix/mechano-transducive cascade in fibrosis bioRxiv 2026 biorxiv.org/content/10.64898โ€ฆ
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ื‘ืงืฉื” ืžื™ื•ื—ื“ืช...ืื ื ืฉืชืคื• ื•ื”ืคื™ืฆื• ื›ื“ื™ ืฉื™ื’ื™ืข ืœื›ืžื” ืฉื™ื•ืชืจ ืžื˜ื•ืคืœื™ื. ืื™ ืกืคื™ืงืช ืœื‘ ืžืชืคืชื—ืช ื‘-1 ืžืชื•ืš ื›ืœ 4 ืื ืฉื™ื ื‘ืžื”ืœืš ื—ื™ื™ื”ื. ื‘-15/7/2026 ื™ื•ื ืจื‘ื™ืขื™ ื‘-11:00 ืžืงื™ื™ืžื™ื ืืช ื›ื ืก ื”ืžื˜ื•ืคืœื™ื ื”ืจืืฉื•ืŸ ื‘ืื™ ืกืคื™ืงืช ื”ืœื‘ ื‘ืจืžื‘"ื ื•ื‘ืฉื™ืชื•ืฃ ืขื ื”ื—ื•ื’ ืœืื™ ืกืคื™ืงืช ื”ืœื‘ ื‘ืื™ื’ื•ื“ ื”ืงืจื“ื™ื•ืœื•ื’ื™. ื”ื™ืจืฉืžื• ืขื›ืฉื™ื• ื•ื”ืฆื˜ืจืคื• ... rambam-patient-hub.lovable.aโ€ฆ ื”ื›ื ืก ืœืจื’ืœ ืคืชื™ื—ืช ืžืจื›ื– ื—ื“ืฉ ื‘ืจืžื‘"ื ืœืžื ื™ืขื” ื•ื˜ื™ืคื•ืœ ื‘ืื™ ืกืคื™ืงืช ื”ืœื‘ ื‘ื›ืœ ืฉืœื‘ื™ ื”ืžื—ืœื”. ืฉื™ืงื•ื ื•ืคืขื™ืœื•ืช ื’ื•ืคื ื™ืช ืžื•ื ืขืช, ืžืจืคืื•ืช, ื˜ื™ืคื•ืœ ืืžื‘ื•ืœื˜ื•ืจื™ ืžืชืงื“ื, ื˜ื™ืคื•ืœ ื•ื ื™ื˜ื•ืจ ื“ื™ื’ื˜ืœื™, ืžื‘ื—ื ื™ ืžืืžืฅ ืœื‘-ืจื™ืื”, ืฆื™ื ืชื•ืจื™ื ื”ืžื•ื“ื™ื ืžื™ื™ื, ืžืจื›ื– ื˜ื›ื ื•ืœื•ื’ื™ื•ืช ืžืชืงื“ืžื•ืช, ื˜ื™ืคื•ืœ ื‘ืชืžื™ื›ื” ืžื›ื ื™ืช ื–ืžื ื™ืช ื•ืงื‘ื•ืขื” (LVAD) ื•ื‘ืงืจื•ื‘ ื’ื ื˜ื™ืคื•ืœ ื ืžืจืฅ ืœืื™ ืกืคื™ืงืช ื”ืœื‘.
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Join us in Minneapolis for the 2026 ISHR North American Section Meeting! ๐Ÿ“ Minneapolis, MN ๐Ÿ“… May 31โ€“June 3, 2026 Promoting the next generation of basic and translational scientists. Reserve your spot today! #ISHRNAS2026 ishrnorthamerican.org/meetinโ€ฆ
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Kehat Lab retweeted
Ghiringhelli et al bioengineered a human-like #atrial heart model that reproduces complex #arrhythmias & can be precisely controlled with light (#optogenetics). Learn about this new platform for studying #AFib at ahajrnls.org/4tVnVCr
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Kehat Lab retweeted
What Mr. Trumpโ€™s career in business and politics has made clear is he understands one concept better than any other: leverage. open.substack.com/pub/thomasโ€ฆ
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Huge congrats to Dr. Jop van Berlo (@UMNews) and Dr. Silvia Guatimosim (UFMG) on receiving the @American_Heart International Visiting Professor Award. Theyโ€™re combining forces to tackle the complexities of cardiac remodeling and molecular cardiology. #Cardionerds #UMNresearch
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Kehat Lab retweeted
Replying to @Ramihdd
@Ramihdd & colleagues by charting the heart cell #proteome & using #CRISPR for precise validation, identified a key protein that sustains the heart #proteostasis & preserves #mitochondrial protein levels. Find out more at ahajrnls.org/3NFIQJG @KehatLab
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New #SkeletalMuscle paper: FibroTrack: a standalone deep learning platform for automated fibrosis quantification in muscle and cardiac histology. tinyurl.com/4vt9f6z4
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Finally out: We used CRISPRa/i to show that virtually ANY genomic site can become regulatory for cardiac genesโ€”even without accessibility or active marks. TF recruitment remodeled chromatin & changed expression up to 70 kb away. doi: 10.1016/j.isci.2025.114040
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Tucker is indeed a scavenger, and the carcass he ransacks is the once great tradition of conservative thought in this country. thomasvondriska.substack.comโ€ฆ
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Kehat Lab retweeted
1/ Can #Axolotls teach us new things about #HeartRegeneration? A great collaboration between @Tanaxolotl and Miguel Torres lab. Weโ€™re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that? doi.org/10.64898/2025.12.21.โ€ฆ

ALT Heart Love GIF

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Excited to launch the Landau-Levi Lab at @TechnionLive ! We develop organ-on-a-chip systems focused on cardiac and multi-organ interactions and the role of immune cells in shaping tissue function. Learn more: thelandaulab.com
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We look forward to welcoming you in #Birmingham @VisitBritain @ISHR_ES @unibirmingham
Abstract submission and registration now open!! uobevents.eventsair.com/39thโ€ฆ Travel awards for PhD students are available - see the website for information #CardioResearch #ECR @ISHR_ECI @IshrMci @ISHR_NAS @JMCCardiology @jmcc @BSCResearch
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Quantifying cardiomyocyte contraction & nuclear deformation interaction reveals nucleus-damaging mechanism underlying LMNA cardiomyopathy ๐Ÿ“ท @AmiadDaria & @julieheffler et al @WeillCornell @PennMedicine in @NatureCVR โžก๏ธ bpod.org.uk/archive/2025/10/โ€ฆ
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