Grateful to @ImmunityCP, Joshua McKeever and Andrew Koh for the thoughtful Preview on our recent paper tinyurl.com/39hhmxuj summarizing our work beautifully "Chromatin triggers tissue-specific immunity in 3D” tinyurl.com/sczzz3bm

ft. @atishay_jay (@pennbioeng), @YeqiaoZhou, @MFMich1, Jorge Henao-Mejia, @bfariabi (@PennPathLabMed), @ysora90, Bereketab Abeje, Aditi Chandra, Julia Wald, @arjunrajlab & @golnaz_v (@PennGenetics) @UPenn_I3H @PennEpiInst @PennIDOM @PennCancer @ImmunityCP cell.com/immunity/fulltext/S…

🚨 We’re hiring a postdoctoral research associate! 🚨 The Ryan Lab at Trinity College Dublin is recruiting a Postdoctoral Research Associate to join our new team in the School of Biochemistry and Immunology, based in the Trinity Biomedical Sciences Institute for 2026/2027. This is a great opportunity for scientists with a PhD interested in mitochondrial biology, immunology, inflammation, infection, metabolism, or primary mitochondrial disease. The position will be available for 2 years in the first instance with the potential for extension. The role will aim to understand how pathogenic mitochondrial DNA mutations reshape the innate immune response to infection ex vivo and in vivo. The successful candidate will contribute to a programme involving: 🧫 Primary macrophage culture 🐭Mouse model-linked infection studies 🔥 Inflammatory and infection-associated assays 📊 Cytokine, metabolic, and immunological readouts 🧬 Molecular biology and genotyping 🔬 A growing programme in mitochondrial immunometabolism 📍 Location: Trinity Biomedical Sciences Institute, Trinity College Dublin 📅 Anticipated start: Flexible, ideally November 2026-January 2027 ⏰ Closing date: 12 noon, 07 October 2026 Please share widely and do get in touch if you think you might be a great fit! To apply: Applicants should submit a full CV plus a short cover letter to include the names and contact details of 2 referees (including email addresses), to:- Dr. Dylan Ryan ryand67@tcd.ie Please use the subject line: Postdoctoral Research Fellow Application – Ryan Lab. Important: Applications by private Social Media messages will not be considered and will not be responded to. Only applicants invited to interview will hear back from us.

Ça s'appelle faire du clientélisme, et non pas "changer"

1/ 🚨 Our new paper in @ImmunityCP ! How does cytokine signaling rewire the 3D genome as T cells choose their fate? We traced the disease-associated Ets1–Fli1 enhancer hub in single cells — one allele at a time — with super-resolution ORCA imaging. cell.com/immunity/fulltext/S…

Hey @amazon can you please explain to me why I still have 4h to add stuff to my order that hasn’t been shipped yet but CANT CANCEL IT because it’s « TOO LATE » ?!

Nous reviendrons. 🇫🇷🙏🏽

Dueling fan bases at the Rocky Steps 👀 🇫🇷 🇮🇶

The French Air Force aerobatic team, Patrouille de France, conducted a major flyover in New York City (coming from near West Point) this morning, as part of their “Liberté 250” tour celebrating American independence. 🇫🇷 🇺🇸

#News for #Investors and #Media: Today, we are announcing that one of our vaccines has been approved for an expanded population by the Japanese Ministry of Health, Labour and Welfare (MHLW). Learn more: gsk.to/3PKzP3i

scArchon: a scalable benchmarking framework for assessing single-cell perturbation models link.springer.com/article/10…

S’il y a un navire de croisière néerlandais contaminé par un virus au large du Cap Vert, pour le grand infectiologue @JLMelenchon, c’est la faute d’@EmmanuelMacron. Le niveau de populisme imbécile de ce pantin cacochyme est incommensurable.

🚨 #Hiring: Staff Scientist/Postdoc (Non-PI) – Madrid 🇪🇸 Translational oncology: tumor biology, biomarkers & precision medicine. PhD + experience in molecular biology & preclinical models required. 👉 Apply bsoldevilla.imas12@h12o.es rolinferrer.imas12@h12o.es

🌟 𝟐𝟎𝟐𝟔 𝐒𝐨𝐮𝐭𝐡𝐰𝐞𝐬𝐭 𝐃𝐢𝐯𝐢𝐬𝐢𝐨𝐧 𝐂𝐡𝐚𝐦𝐩𝐢𝐨𝐧𝐬 🌟

🚨 New paper out in @NatMetabolism! Chapter 2 of our mitochondria zonation story (following our 2024 Nature Communications work). We asked how zonated liver mitochondria adapt when lipid flux surges. 🧵👇 nature.com/articles/s42255-0…

Ready to make the switch? claude.com/import-memory

Oops! Please do NOT share, got it? 😉

🎥 Quand on vous dit que tout est fake à l’Extrême-Droite. Voici un exemple avec la camapgne pour Paris de @knafo_sarah qui a tout pompé de la campagne de Zohran Mamdani pour New-York. C'est un plagiat absolu, rien de neuf que du vieux comme les idées de Reconquête. Regardez⤵️‼️

oh so now y'all like france

Cool new paper from the @ozannelab showing maternal iron homeostasis, not placental dysfunction, is associated with fetal hypoxia at e13.5 in obese mouse pregnancy physoc.onlinelibrary.wiley.c…