MIT Institute for Medical Engineering and Science (IMES): we work at the convergence of engineering, science, and translational medicine.

Cambridge, MA
Auditory stimuli delivered in phase with peaks of #EEG slow waves in the brain increased cerebrospinal fluid (#CSF) flow in healthy adults napping inside an MRI machine, offering insight to treating dysfunctional CSF flow. @MIT_IMES @BostonU_BME scim.ag/4r1JFfe
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Welcome first-year students and welcome back to all returning students! #ThisisMIT
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Looking forward, we are excited to create quantitative fate maps of tumor evolution, and learn how other aspects of tumor progression - such as genomic instability - unfold over space and time. If you find these directions exciting too, we're recruiting postdocs so get in touch!
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This was a years-long endeavor co-led by my stellar colleague @sundakao that started during the pandemic. It was an incredibly fun project across multiple labs including @dianyang1117 @insitubiology @JswLab and @YosefLab. I am deeply grateful to these collaborators and mentors
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This platform integrates our Cas9 lineage tracing technology with new spatial genomics platforms pioneered by Fei Chen's group (@insitubiology). These platforms perform unbiased capture of poly-A transcripts, enabling simultaneous spatial mapping of lineage and gene expression.
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It's been known for decades that a tumor's spatial structure carries immense prognostic value. Yet, the spatial evolution of tumors has been difficult to track over time. Here, we introduce a new platform for performing spatial lineage tracing in tumors: bit.ly/4zUEsdk
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I am very excited to share that our latest work on spatial lineage-tracing in the KP lung adenocarcinoma model has been published in @NatureGenet today! This is the latest work from my lab at @MITBiology @kochinstitute @MIT_IMES. Thread below👇
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Lydia Bourouiba, a professor in @MIT_CEE, @MITMechE, and @MIT_IMES, received the 2026 MathWorks Faculty Research Innovation Fellowship (FRIF). 📸: Conor McArdle engineering.mit.edu/news/lyd…
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When it comes to AI-assisted medical diagnosis, one size may not fit all. A new study from @MarzyehGhassemi and team found that AI explanations affect clinicians and non-experts differently—highlighting the need to design AI support around user expertise. bit.ly/4gv0jR7
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In a new Science Translational Medicine study by a team including MIT-Novo Nordisk Postdoc Seyed Majed Modaresi and Prof. James Collins from @MITdeptofBE, researchers used deep learning to identify promising new compounds against drug-resistant gonorrhea. wyss.harvard.edu/news/machin…
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New paper from my group at @kochinstitute @MIT_IMES @MITBiology! I am thrilled to share that our paper describing scAmp, a new method for analyzing extrachromosomal DNA amplifications at single-cell resolution, has been published in @NatureComms. Thread below 👇
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Excited to share our new @JACCJournals paper: OCT + DL can improve prediction of response to IVL & support patient-specific intervention planning. Congrats to Yiqing Liu & Elazer Edelman (@MIT_IMES), and thanks to @NIH & @ShockwaveIVL. @BrighamCardiac @MassGenBrigham @harvardmed
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The visionary PhysioNet platform turns 25+--a system developed @MIT + @mit_hst in the 1970s. It has become one of the most comprehensive biomedical and clinical data repositories in existence! @MITEngineering Learn more bit.ly/4fOeVJL
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We're proud of Emery N. Brown, who recently received @MIT 's highest faculty honor: Institute Professor! He is now one of 12, inc. @MIT_IMES founding dir. Arup Chakraborty. Congrats to the brilliant physician + neuroscientist! @mit_hst bit.ly/3RS1hx5
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1. Can hydrogels breathe? In our new Nature paper, we show that only 2-4 wt% aerogels can enhance hydrogel air permeability by more than 10× through viscoelastic phase separation—while preserving water-rich, tissue-like properties. nature.com/articles/s41586-0…
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4. Congratulations to @XiaoYunYan, @shucong_li_hhh, and all coauthors and collaborators for this exciting work. @MIT @MITMechE @MIT_IMES @MIT_CEE @MITEngineering @mit_nano
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.@MIT_IMES pioneers research and education at the intersection of engineering, science and medicine to transform human health for all. @mit_hst empowers future clinician-scientists. @MIT #CuriousityOnAMission
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We are looking for a Senior Lecturer/Director of Education! Responsibilities inc. overseeing @mit_hst academic affairs, educational policy+curriculum development. Help educate the next generation of clinician-scientists! Apply here: careers.peopleclick.com/care…
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A new study published in @ScienceMagazine led by Alex Shalek, director of @MIT_IMES, shows how a key T cell protein called LAT keeps immune responses in balance. imes.mit.edu/news-events/sha…
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We were pleased with the overwhelming response to the talk by Geoffrey Hinton (known as the godfather of AI) "Are we creating alien beings?" (@MIT_IMES )! The video is now available here: bit.ly/3S670PK To sign up for future lectures: bit.ly/3Sr8a8p
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