Postdoc @HarvardMed. CryoEM and anything chromatin or transcription. views are my own
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Jon Markert retweeted
I’m very happy to share our latest work on the ParABS system. We investigated the dynamic interaction between the ATPase ParA and the CTPase ParB mediating chromosome segregation in Myxococcus xanthus. I would like to thank all the people involved.
Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation biorxiv.org/content/10.1101/… #biorxiv_micrbio
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Our work providing the mechanistic basis for SETD2 function is finally out! We demonstrate SETD2 requires active transcription to facilitate H3K36me3 deposition!
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @MarkertJon tinyurl.com/setd2
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Jon Markert retweeted
Excited that our work on transcription-coupled DNA repair is now published @CellCellPress! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples stalled Pol II to TFIIH. 🧬🐸
➡️ cell.com/cell/fulltext/S0092…
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Jon Markert retweeted
Hiring! Seeking motivated postdocs, technicians, and graduate students for our new lab at the University of Miami Miller School of Medicine. Dive into protein chemistry and chemical proteomics to explore cancer and aging. #ZwangLab #UMiami #Research
zawanglab.com/
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Jon Markert retweeted
I am happy to share that I will be starting an assistant professor position at the Van Andel Research Institute @VAInstitute in the Department of Neurodegenerative Science. My lab is opening in July, and I am currently hiring: vai.wd1.myworkdayjobs.com/en… and vai.wd1.myworkdayjobs.com/en…
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Jon Markert retweeted
biology methods for understanding protein post-translational modifications in cancer & aging. Excited for this new journey! Looking to hire passionate postdocs, technicians, and grad students. Join us! [Main Webpage: zawanglab.com/] #research #Careers
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Congratulations @hoyer_melissa and everyone else involved!
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Jon Markert retweeted
Our paper on the structure of the complete Rpd3S-nucleosome complex is now out in Nat Comm: rdcu.be/ds6k1. Congrats to @MarkertJon and co-corresponding author @seyvos ! This is the second HDAC-nucleosome structure from Jon this year. Amazing!
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Jon Markert retweeted
Our story on the complete Rpd3S-nucleosome complex is now online on Biorxiv: biorxiv.org/content/10.1101/…
We visualize the S. cerevisiae Rpd3S complex bound to a nucleosome including the "evasive" Ume1 subunit!
Congrats, @MarkertJon! Thank you @seyvos for a great collaboration.
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Jon Markert retweeted
Our latest publication reports the cryo-EM structures of the human Polα-Primase DNA elongation complexes - rdcu.be/c96yY A Lim lab X Tahirov lab collaboration led by @QixiangHe and Andrey. Thank you, @sarakosman & @NatureSMB, for working with us! Please RT to share! 1/4
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Jon Markert retweeted
Mechanism of histone H2B monoubiquitination by Bre1 biorxiv.org/content/10.1101/…
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Jon Markert retweeted
Congratulations to Farnung lab PhD Candidate Felix Steinruecke! He has been selected to receive a 2023 NSF Graduate Research Fellowship. Amazing!
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Jon Markert retweeted
So excited to share that my thesis work is out now at @MolecularCell! Karen @AdelmanLab and I show that U1 snRNP increases RNA Pol II elongation rate within AT-rich introns, thereby reducing the likelihood of Pol II termination or arrest. Highlights below! authors.elsevier.com/c/1gobY…
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Jon Markert retweeted
Binding to nucleosome poises SIRT6 for histone H3 de-acetylation biorxiv.org/cgi/content/shor…
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RT @valendraica: I’m excited to share a new manuscript on Sirtuin6-nucleosome structure, a result of a great collaboration between @Peterso…
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Jon Markert retweeted
Exciting complimentary nucleosome-SIRT6 work by @valendraica, Song Tan and Craig Peterson labs: biorxiv.org/content/10.1101/… Interesting differences in H2A dynamics in the absence of NAD vs. our catalytically poised state. Our story: pubs.acs.org/doi/10.1021/jac…
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Congrats to Shawn and team!! First we learn from @LugerLab about eukaryotic histones…then virus…and now…bacteria!?!? What next???
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Jon Markert retweeted
The Effects of Histone H2B ubiquitylations and H3K79me3 on Transcription Elongation biorxiv.org/cgi/content/shor… #bioRxiv
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Jon Markert retweeted
The Kurumizaka ERATO project is organizing a virtual International Symposium titled "Chromatin Architecture: Structure and Function" on Jan. 24-25, 2023. Registration is open now! Deadline for abstracts submission for posters is Jan. 9, 2023. Check it out! bit.ly/3XPvQS8
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Jon Markert retweeted
Mechanism of RanGTP priming the release of H2A-H2B from Kap114 and Importin-9 biorxiv.org/cgi/content/shor…
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