Associate Professor @UCLA. #iPSC, #organoids, #vascular development, regeneration, and aging
Los Angeles, CA
- Tweets 312
- Following 778
- Followers 1,050
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Our study shows that hyperoxia drives lung endothelial cells into a non-regenerative state through isoform specific disruption of NTRK2, and that isoform-targeted correction restores vascular regeneration and enables disease modifying lung repair. Grateful to all contributors 🎉
Online Now! Rebalancing NTRK2 isoforms promotes vascular regeneration in bronchopulmonary dysplasia dlvr.it/TQ0H2z #stemcells
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Mingxia Gu retweeted
What a tour de force paper - everyone should read this one! congrats @MingxiaGu!
Online Now! Rebalancing NTRK2 isoforms promotes vascular regeneration in bronchopulmonary dysplasia dlvr.it/TQ0H2z #stemcells
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Mingxia Gu retweeted
Join me next week in @vascularbiology's InFocus Session, where I'll be giving a short presentation on my thesis project 'Distinct Functional Consequences of FOXF1 Mutations in Capillary Development'. Registration is free: shorturl.at/T12dx
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Meet Dr. Mingxia Gu, a @UCLA scientist who uses stem cells to engineer mini versions of human hearts and lungs.
Here, she talks about her mission to reverse aging, how her father inspires her science and the silver lining to living with face blindness.➡️ ucla.in/44GQRn9
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Check out our Comment in @Nature on #NAMs (or #NewApproachMethodologies) and #CTiD (or #ClinicalTrialinDish) that better capture human genetics and shift mindsets or research.
nature.com/articles/d41586-0…
@ProfValS @lucy_os @Stanford_ChEMH @StanfordDeptMed @GreenstoneBio @US_FDA @NIH
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🚨 Please RT!
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF1064…
#Neuroscience #Postdoc
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Excited to co-organize the Keystone Symposium “Stem Cell Models in Embryology” with Jianping Fu and @EbisuyaMiki! Join us Feb 17–20, 2026 at Asilomar to explore cutting-edge advances in stem cell–derived embryo models. Spread the word! keysym.us/KSEmbryology26 #KSEmbryology26
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Drs. @SimonMiao6, Nicole Pek (@two_cells), and Drs. Minzhe Guo and @MingxiaGu's labs co-differentiated mesoderm and endoderm in the same spheroid to vascularize lung and intestinal #organoids!
@CellCellPress article: bit.ly/3H1ar4V
Discussion: bit.ly/44YrzjU
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Our Cell paper is now online!! 💡We share a mesoderm-endoderm co-differentiation strategy to achieve organ-specific #endothelial & #mesenchymal cells in vascularized #lung and intestinal #organoids. 🔗sciencedirect.com/science/ar…
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New in @CellCellPress: Scientists have created the first 3D mini-lungs complete with their own functioning blood vessel networks, unlocking new insights for pulmonary vascular disease. ➡️ bit.ly/4kmCrxB
#Organoids #LungOrganoids #StemCellResearch
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Mingxia Gu retweeted
First Lung Organoid with Organ-Specific Blood Vessels. Congrats to the team @CuSTOMOrganoids at #CincinnatiChildrens! #LungOrganoids #StemCellMedicine #OrganoidMedicine. Study @CellCellPress: cell.com/cell/abstract/S0092… Blog: scienceblog.cincinnatichildr…
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Excited to share our recent work on organoid vascularization, now out in @CellCellPress! Grateful to all our amazing collaborators who made this possible! @CuSTOM_CCHMC @UCLAstemcell
Congrats @MingxiaGu and all the teams collaborating on this latest advance in stem cell and lung organoid research, just out @CellCellPress! "Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids" cell.com/cell/fulltext/S0092…
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Excited to share our latest study showing that restoring the balance between NTRK2 isoforms offers a promising therapeutic approach to promote pulmonary vascular regeneration! biorxiv.org/content/10.1101/…
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Dr. Hasan Al Reza and a team in the @TakebeLab at @CuSTOMOrganoids developed multi-zonal liver #organoids!
This model can recapitulate hepatic architecture relevant to liver development and disease.
Article: go.nature.com/3Y1UkJU
Discussion: bit.ly/4jWDX9T
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Mingxia Gu retweeted
Our latest paper on #cardiac #fibrosis is out today in @Nature. Congrats to @StanfordCVI @StanfordMed researchers led by @Sangkyun_Cho and @SiyeonRhee. And special thanks to computational scientists @GreenstoneBio for providing #AI #drugdiscovery.
Link: nature.com/articles/s41586-0…
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I and @kathyolui organize Hematology & Immunology symposium at CUHK. June 10. International speakers @MingxiaGu @CellReproLab @LLizhong many others cover blood origin, cardiac organoid, vascular organoid, next-gen CAR, immunotherapy, immune labOnChip, lineage tracing embryos
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Grateful for the chance to talk with Janet Rossant and @MingxiaGu ! In this @stemcellreports podcast episode we touch on the roles of the #vasculature in the #lung and I talk a bit about what comes next! @jlugiessen @HeroldLab @CPI_ExStra @StainierLab
The newest podcast is now live. Listen here tinyurl.com/ej429twb or wherever you download your favorite podcast. @ISSCR @paolo_panza @StainierLab @MingxiaGu @UCLAstemcell
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When you read about layoffs & terminations of HHS, NIH, CDC employees - remember: these are people, with families, plans, who worked for the health & safety, of the American people. Now they're thrown by the wayside, by those who never cared about anything but themselves.
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New preprint: The first whole-body map of both DNA methylation and 3D genome organization at single-cell resolution across 16 human tissues, with in-depth analyses of cell type diversity of these epigenome modalities at unprecedented resolutions. (1/5)
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Truly appreciate the opportunity to discuss the development of both lung microvasculature and academic careers—navigating challenges and opportunities in science and beyond! @ISSCR @UCLAstemcell
The newest podcast is now live. Listen here tinyurl.com/ej429twb or wherever you download your favorite podcast. @ISSCR @paolo_panza @StainierLab @MingxiaGu @UCLAstemcell
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