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Nature Biotechnology retweeted
What makes endometriosis so hard to detect, even when its impact is unmistakable?
In @NatureBiotech, Carrie Arnold explores the search for biological clues in blood and menstrual fluid, including HerAnova's blood-based approach.
Our Chief Medical Officer – Head of Diagnostics, Farideh Bischoff, PhD, shares why diagnosis remains a major unmet need and why a single biological marker may not be enough to detect a complex disease.
Read what researchers are looking for, and why it matters: nature.com/articles/s41587-0…
#Endometriosis #WomensHealth #Diagnostics
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Photolabile oligonucleotides with topological light gradients enable spatially resolved single-cell transcriptomics and epigenomics nature.com/articles/s41587-0…
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Recent patents relating to systems, methods and compositions for use in synthetic biology nature.com/articles/s41587-0…
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In Brief: US @NSF launches a pilot program that gives doctoral students real-world experience in industry as part of their PhD nature.com/articles/s41587-0…
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Sustained epigenetic silencing in monkeys is made more efficient with optimized regulators go.nature.com/46uDMyK
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Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment nature.com/articles/s41587-0…
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Blood protein analysis suggests a lung disease drug could be fighting aging at the same time #NBTintheNews medicalxpress.com/news/2026-…
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Rentosertib shifts multiple proteomic aging clocks toward younger age profiles in IPF trial #NBTintheNews news-medical.net/news/202609…
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A breast cancer drug linked with a test to detect ESR1 mutations in circulating tumor DNA is one of a wave of new drugs developed to tackle resistance to estrogen-receptor-targeted therapies nature.com/articles/s41587-0…
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Guidance for optimizing lipid nanoparticle formulations is derived using sophisticated biophysical techniques go.nature.com/4oTt639
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Research Highlight: Biomimetic cells for studying T cell mechanotransduction nature.com/articles/s41587-0…
kpiCells: biomimetic artificial cells for investigating mechanoregulation in cell-cell interactions.
nature.com/articles/s41592-0…
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A method to label cultured human embryos finds chromosome segregation errors in placenta-fated cells go.nature.com/3JdRdu8
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An optimized approach for live imaging of human embryos enables visualization of mitotic errors during blastocyst development #NBTNV go.nature.com/48PpE4O
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In Brief: @FDA approves @Replimune's #Tudriqev, an oncolytic immunotherapy for treating patients with unresectable advanced melanoma whose disease has progressed after PD-1 immunotherapy nature.com/articles/s41587-0…
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Pharmaceutical products with device-only patents: a cross-sectional analysis nature.com/articles/s41587-0…
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A new generation of RNA therapies delivered by lipid nanoparticles takes aim at extrahepatic tissues nature.com/articles/s41587-0…
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Nature Biotechnology retweeted
細菌の成長と色素生産を直結 希少動物色素キサントンマチンの微生物生産を実現🧬🎨
Bradley S. Mooreらの@naturebiotech #論文
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin
nature.com/articles/s41587-0…
論文閲覧用リンク：rdcu.be/cqLqR5vGP9Xa
#合成生物学 #代謝工学
ALT Fig. 2: Design and characterization of PUMA.
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Nature Biotechnology retweeted
NonExomics is featured in @NatureBiotech’s September survey of the dark proteome, among the companies turning the dark genome into new drug targets.
~3,000 novel dark antigens across 1,365 human diseases, prioritized and experimentally validated.
nature.com/articles/s41587-0…
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Property guidance for protein sequence generative models with ProteinGuide nature.com/articles/s41587-0…
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.@UCBerkeley researchers developed ProteinGuide, an AI strategy that steers protein generative models toward specific properties using experimental data—without retraining the underlying models.
Read more about this research in QB3-Berkeley faculty labs: bit.ly/4AlhcFC
ALT Graphic illustrating how ProteinGuide was tested on adenine base editors: In the first round, generative models produced a library of variants that were experimentally tested for editing activity; ProteinGuide then used those results to guide a second round of designs toward higher activity.
ALT Side-by-side headshots of Maria Lukarska (left, a postdoctoral scholar in Professor Dave Savage's lab) and Junhao Xiong (right, a recently graduated PhD student in Professor Jennifer Listgarten’s lab).
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Nature Biotechnology retweeted
Featured in @NatureBiotech: CEO John Lepore, MD, explains how novel proteins beyond the annotated proteome could open new paths for medicines. ProFound is building the largest atlas of novel proteins to help advance first-in-class therapies. nature.com/articles/s41587-0…
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