Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
London, UK
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🎉 Our 25th Anniversary Issue is now live! 🎉🥳
Featuring #Reviews on
- 3D tumour atlases
- The systemic impact of EVs
- Pyroptosis & antitumour immunity
#Roadmap on
- Early-onset CRC prevention
Plus #Viepoints #Comments &#WorldView
Check it out 👇
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Viral mimicry activates antiviral immune responses through endogenous nucleic acids in the cytosol. Chen et al. discuss how tumours suppress these responses and why escape from #ViralMimicry may be a key feature of tumour evolution.
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#Editorial 🎉Celebrating 25 years of #NatureReviewsCancer🎉
On this milestone we contemplate how our view of cancer has changed over the past 25 years and speculate on what the future holds.🥳
Thanks to our authors & readers who made this possible!
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NEW content online! Replication stress in cancer: origins, consequences and therapeutic opportunities dlvr.it/TVbfrj
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#Review 🚨
How can #PopulationGenetics help decode tumour evolution? This Review discusses how mutation, selection and drift shape cancer genomes and how evolutionary models can reveal tumour dynamics and trajectories from sequencing data.
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NEW content online! From blunt-force treatment to precision: 25 years of transformation in cancer research dlvr.it/TVbQny
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#ViewPoint 🎉 Celebrating 25 years of NRC!
Six leaders in cancer research reflect on the ideas that transformed their field, those that fell short of expectations and the challenges that remain.
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Read how genotype and phenotype co-evolve during cancer progression with insights from single-cell multimodal technologies and phylogenetic approaches, revealing vulnerabilities in mutant clones.
@TamaraPrietoF @FrancoIzzo85 @landau_lab
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#Neutrophils can impact tumor growth. This Review explores their role in tumor progression and #metastasis, compares it to other biological contexts, and discusses new strategies for targeting neutrophil biology in cancer.
@StanfordMed
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🚨 Early-onset colorectal cancer is on the rise globally. This #Roadmap highlights knowledge gaps, proposes a model for risk factor discovery and emphasizes the importance of patient engagement and transdisciplinary science in combating this trend.
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Ciriello, Oricchio&Co discuss how remodelling the 3D #chromatin structure in cancer is both a cause & consequence of genetic and epigenetic alterations and highlight how chromatin 3D conformation might be exploited for diagnosis and therapy.
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NEW content online! Viral mimicry escape as a necessary feature of malignant transformation dlvr.it/TVTzMM
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#JournalClub 🚨
Yolanda Chirino and Estefany Medina-Reyes discuss a study linking e-cigarette exposure to mechanistic markers of carcinogenesis and the implications for cancer prevention research.
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Nature Reviews Cancer retweeted
The basis for early-onset colon cancer, now showing up throughout the world, is poorly understood. The Table below is the ranking of countries affected. This new review gets at the potential causes and what needs to be done.
nature.com/articles/s41568-0…
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NEW content online! Making breast cancer innovation deliver for every woman dlvr.it/TVRL6J
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#Viewpoint 🎉 Celebrating #25yrs!
Read insights from six emerging cancer researcherson the #future of their field, as they challenge traditions and propose innovative approaches for the next 25 years.
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Nature Reviews Cancer retweeted
Rescue and recovery responders of the WTC disaster suffer 9/11-related cancers. Zeig-Owens&Prezant @FDNY @EinsteinMed summarize cancer incidence and outcome studies in this population, highligting the need for a dedicated health programme response.
go.nature.com/3XnAhEh
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#ResearchHighlight🚨Expanding the reach of #menin inhibitors
A study shows that menin inhibition impairs #megakaryocyte differentiation, suppresses myelofibrosis and improves disease features in preclinical myeloproliferative neoplasm (#MPN) models.
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NEW content online! A guide to understanding tumour evolution through the lens of population genetics dlvr.it/TVPTqR
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#Comment🚨
Swanton&Co @CharlesSwanton highlight the histories of EGFR, HER2, CDK4/6 and RAS, and discusses how sustained investment in discovery science continues to generate clinical benefit through new drugs, indications and treatment combinations.
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