Aspiring physician-scientist, Cardiology Fellow at UPenn. Member of the Arany Lab Sarnoff Alumni. AECOM alumni.

Grateful to have worked with such a dedicated team in the @AranyLab and @MarguliesLab to bring this discovery to fruition. And thanks @SarnoffCardio for all your support!
We've not understood why SGLT2 drugs (like empagliflozin, Jardiance) have marked protective heart benefit. Today @ScienceMagazine a mechanism unraveled for improving cardiac metabolism and fuel efficiency science.org/doi/10.1126/scie…
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It's almost as if NIH has been taken over by rouge ideologues. Drastic cuts in indirects are like cutting off your nose to spite the face. For mere $4B in "savings," this will end the dominance of American research universities, the best damn value for American tax payers. And when did doing life-saving medical research & providing care to the neediest make you a dinosaur?
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Now out in @JAMA_current: How well do individual risk estimates from different CHD polygenic scores agree? Grateful to work on this with a dream team of mentors and co-authors @damrauer @MGLevin @bpasaniuc @MarylynRitchie @dokyoon_kim @bvoight28 @BoulierKristin @karlkeat
🚨 Our work exploring polygenic risk scores for Coronary Heart Disease is now out in @JAMA_current and presented at #AHA24 by all-star @SarnoffCardio fellow @sabramowitz_: jamanetwork.com/journals/jam…
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Are you an MD student interested in research? Would strongly consider applying for the @SarnoffCardio Fellowship. Scientific immersion with *unparalleled* longitudinal mentorship & exceptional peer network career-long. sarnofffellowship.com/ My biggest regret in med school was not participating despite guidance from mentors. Now I'm thrilled to join this vibrant community on the Scientific Committee. Nice summary of the program ahajournals.org/doi/10.1161/… @CircAHA Track record of successful physician-scientists going through this program is impressive - the recipe of immersion + longitudinal engagement/sponsorship/mentorship works very well
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Our Story is Out - on BioRxiv! Humbled to have worked with such a great team of scientists to investigating how #SGLT2 inhibitors provoke their astounding cardiac benefits.
We think this one is groundbreaking: Do you wonder how #SGLT2 inhibitors protect from heart failure? We show that #empagliflozen directly activates PANK1, rate-limiting for CoA synthesis, in human hearts. You read it here first! biorxiv.org/content/10.1101/…
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Destiney Kirby, MPH today💃🏽 Looking forward to adding the MD next year!
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So proud !! congratulations Megan and Quentin -- newest Aranylab graduates. Watch out world, here they come! @MeganCBlair @CAMBUpenn
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Very proud of @CampainJoseph, outstanding Sarnoff Fellow in my lab this year from UTSW @josephahill who just presented his work on O2 kinetics in HFpEF compared to a community cohort at the 43rd Annual Sarnoff Scientific Meeting . @Raj_MalhotraMD @MGHHeartHeath @MGHMedicine
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What happens to non-cardiomyocytes in the heart with aerobic exercise? Check out our new review paper in @JSHS_MedHealth from the @rosenzweig_a lab @lihaobo @JSawallaGusehMD @sashalkuznet
+1K. What is the cellular cardiovascular response to exercise? Great in-depth review by @LenaETrager on the diversity of cellular response to exercise within the heart. Full Review: buff.ly/3HON5O6 cc: @lihaobo @rosenzweig_a @sashalkuznet
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I don’t usually brag about our residency program, but today I’m gonna make an exception. Like other children’s hospitals, we’re managing a surge in respiratory illness. But unlike most hospitals, we’re gonna pay the residents who work extra overnight/weekend shifts $100/hour.
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Current Sarnoff Fellows and Scholars at the AHA Scientific Sessions!
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Phenomenal talks on #HFpEF here at #AHA22
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Oops wrong link for Danielle - apologies ! @Yoshiko96821
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Barry Sharpless with his second Nobel in chemistry!
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
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Interested in heterologous expression of large numbers of biosynthetic gene clusters? My focus over the past years has been to try to make this process more scalable. Have a look at this new approach, I used it to discover a new antibiotic: conkatamycin nature.com/articles/s41467-0…
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Modeling Heart Failure with Preserved Ejection Fracion (HFpEF) in Rodents: Where do we stand? >3 million in US suffer from it. Accurate preclinical models are critical to develop new drugs. This review by @MTChinMDPhD sets the framework. @FrontDrugDDS frontiersin.org/articles/10.…
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It’s a special kind of joy when you see your cardiomyocytes beating for the first time 🥰 #SarnoffYear #CardioTwitter #WomenInSTEM
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Every now and then I get to put down my stethoscope for a pipe crimper and work in the family business - here with my brother - as I did some time ago. Medicine and plumbing are almost the same thing right?
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