Working on cancer research and cell signalling at the University of Liverpool.
University of Liverpool.
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Ras isoforms and mutants are differentially associated with cancer and developmental disorders. This intro summarises some of the key points.
link.springer.com/protocol/1…
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Ian Prior retweeted
🧠🔬Are passionate about EM, neurons, ageing, neurodegeneration, Drosophila?
Funded 4-year BBSRC NWD PhD to advance neuroscience through vCLEM techniques.
🙏repost this project with
@PriorLab
@Natsansor
@AlisonBeckett11
findaphd.com/phds/project/bb…
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Ian Prior retweeted
Returning to the lab after a great week at @BiochemSoc Small G Proteins in Cellular Signalling and Disease 2025.
Blown away by the high calibre of research on display, and grateful to have been able to showcase our work after years in development.
#BiochemEvent #SGP25
ALT https://www.linkedin.com/posts/hlahiff_biochemevent-biochemawards-sgp25-activity-7345767226265812992-kbmZ?utm_source=share&utm_medium=member_desktop&rcm=ACoAACvmAZkBkaRFPkrRLEJXZsO5NUPHHoZ4Rjo
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My lab and I were at the Small G-Protein conference in Manchester last week. Really lucky to work with such a great team. #BiochemEvent #SGP25
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Great meeting and nice to meet old friends and new. Thanks @BiochemSoc for supporting this.
A huge thank you to all the amazing delegates who joined us for Small G Proteins in Cellular Signalling and Disease 2025 this week! We hope you enjoyed the conference and look forward to seeing you at the next one. #BiochemEvent #SGP25
ALT Group photo
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Great to have Terri from @kraskickers as our opening speaker at the Biochem Soc Small G-protein conference! #BiochemEvent
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Earlybird deadline closes on April 30th. We will be selecting talks from abstracts immediately afterwards so please register now!
Final week for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @BiochemSoc @SmallGTPases Register here: bit.ly/SmallG25
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Final week for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @BiochemSoc @SmallGTPases Register here: bit.ly/SmallG25
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4 weeks left for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @BiochemSoc @SmallGTPases Register here: bit.ly/SmallG25
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6 weeks left for the early bird deadline for the Small G-protein meeting in Manchester. Talks slots available from submitted abstracts. Register here: bit.ly/SmallG25
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Ian Prior retweeted
Thoroughly enjoyable work and some surprise findings! The first journey into the chromosome periphery in mammalian oocytes with @TheMitosisBooth and @wthrll. Great team science with several labs across Institutions @kinetochore and @PriorLab biorxiv.org/content/10.1101/…
1) There has been super work in recent years, from multiple labs - but almost all have centred on a mitotic CP. But what about a CP in meiosis, eg in oocytes! Check out this work - from a great collaborative team! biorxiv.org/content/10.1101/…
@SuzanneMadgwick @kinetochore @UoN_BDI
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Ian Prior retweeted
🆕#TLevelToolkit for UK universities who want to host #TLevel placements, but don't know where to start
📽️ Hear what #TLevel students say about their experience @LivUni @LivUniTechNet @ElearnerMatt
➡️Download your free toolkit buff.ly/4hqcCw6
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Ian Prior retweeted
I have a BBSRC CTP PhD on protein kinases & cancer therapies available to start in Oct 2025. It is a collaboration between my lab @BabrahamInst and @CR_Horizons @BabrahamUK We're a friendly bunch. We like cake. What's not to like? Please RT
babraham.ac.uk/work-and-stud…
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Ian Prior retweeted
#Chromosomes in early prometaphase are longer, have a more granular surface, and lack a primary constriction. From Cisneros-Soberanis, Simpson, Earnshaw et al. @WTcell: hubs.la/Q02Mx5G40
#StructuralBiology #Mitosis #CellDivision
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Ian Prior retweeted
🆕#TLevelToolkit for UK universities who want to host #TLevel placements, but don't know where to start
📽️ Hear from @LivUni @LivUniTechNet @PdGilbert @PriorLab @ElearnerMatt about the benefits of hosting #TLevel placements
➡️Download your free toolkit buff.ly/3MBPpct
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Ian Prior retweeted
An atlas of genetic effects on cellular composition of the tumor microenvironment @NatImmunol
nature.com/articles/s41590-0…
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Ian Prior retweeted
Online Now: Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer dlvr.it/TCXth0
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Ian Prior retweeted
Thrilled to share progress on Ras isoform binders! Using AI-driven protein design, I’ve targeted the challenging, highly charged and disordered C-terminus of Ras. These de novo binders exceed antibody specificity and effectively disrupt Ras signaling. biorxiv.org/content/10.1101/…
ALT Design pipeline for making Ras isoform binders.
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Ian Prior retweeted
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade | Nature Communications nature.com/articles/s41467-0…
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Congratulations @ASmallFi on winning one of the poster prizes at the @FASEBorg Small G-Protein meeting! 👏🏻👏🏻👏🏻 @LivUniISMIB #RGTPSRC
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Grateful for the opportunity to present some of our emerging data on nanoclustering regulators and new Ras variant models #RGTPSRC @FASEBorg @LivUniISMIB
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