RTHM
@RTHM_Health

RTHM is a secure health platform that makes it easy to gather your records, connect the dots with AI, and affordably access treatments.

 Redwood City, CA
linktr.ee/rthm_health
Joined November 2021
529 Photos and videos
Preventing PEM often means looking beyond exertion alone. In this clip, @LBatemanMD from @BatemanHorne discusses approaches that may support baseline function, including improving restorative sleep and using fluids strategically before upright activity. She explains why identifying and managing individual contributors, such as orthostatic intolerance, mast cell activation, immune dysfunction, and recurrent viral reactivation, may help reduce crashes. She also shares how targeted treatments, including antivirals and immunoglobulin, may be considered for select patients based on their individual clinical picture. Join Dr. David Putrino, Dr. Lucinda Bateman, Dr. Jennifer Curtin, and moderator Charlie McCone for the full How to Manage and Treat Post-Exertional Malaise (PEM) webinar. Watch the full webinar recording on our YouTube channel: piped.video/watch?v=Na5znc92…
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For Adam, living with ME/CFS has meant spending years trying to make sense of complex symptoms and treatment options in a healthcare system that does not always fully understand this often life-altering condition. Through RTHM’s AI-powered platform, Adam has been able to ask detailed questions about ME/CFS and the role of Epstein-Barr Virus (EBV), explore current research and potential treatment approaches, and engage in conversations that reflect the complexity of his experience. He has also uploaded years of lab work allowing the platform to organize results, surface patterns and changes over time, and keep track of medications, supplements, and other treatments he has tried. For people managing complex chronic illness, bringing their health history together in one place can make it easier to understand the bigger picture and prepare for more informed conversations with their care team. Create your free account on the HIPAA-compliant RTHM Platform through the link in our bio to upload your health records, explore personalized insights, and access resources for ME/CFS, Long COVID, POTS, MCAS, and other complex chronic conditions. rthm.com
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Study summary on COVID-19's link to thyroid disease risk in active-duty military personnel, highlighting increased risk and need for monitoring.

ALT Study summary on COVID-19's link to thyroid disease risk in active-duty military personnel, highlighting increased risk and need for monitoring.
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This week, we’re highlighting five recent publications that may help explain the biological mechanisms underlying Long COVID, showcase probiotic interventions for fatigue, to haptoglobin blood tests as a biomarker for distinguishing Long COVID subtypes, viral persistence in colorectal tissue with associated local immune dysregulation, changes in movement-related brain activity tied to fatigue and brain fog, and post‑infectious thyroid autoimmunity in active-duty service members. RTHM’s Research Corner helps patients stay up to date on emerging Long COVID research, with studies curated to your health conditions, symptoms, and topics of interest. Not living with Long COVID? You can still personalize your weekly research email by selecting the conditions, symptoms, and topics most relevant to you. Sign up for weekly curated research emails here: rthm.com/research-corner/tag…
Graphic announcing five new research studies focused on Long COVID by rthm.

ALT Graphic announcing five new research studies focused on Long COVID by rthm.

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Research summary on colorectal tissue analysis revealing viral persistence and immune dysregulation in Long COVID patients.

ALT Research summary on colorectal tissue analysis revealing viral persistence and immune dysregulation in Long COVID patients.

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Summary of a study on EEG biomarkers linked to fatigue and brain fog in long COVID, highlighting changes in brain activity during rest and movement.

ALT Summary of a study on EEG biomarkers linked to fatigue and brain fog in long COVID, highlighting changes in brain activity during rest and movement.

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study #4 study #1 Association of Prodromal Parkinson's Disease-Like Features in Long COVID With Dream-Enactment Behaviours study #1 Bei Huang, Eemil Partinen, Yaping Liu, et al. Journal of Sleep Research. 2026. Key Findings: This large-scale international study involving 11,261 participants found that long COVID is associated with a significantly higher burden of prodromal Parkinson's disease (PD)-like features, with long COVID participants showing a 73% increased risk compared to non-COVID-19 individuals. Notably, the emergence or worsening of dream-enactment behaviors (DEBs) further heightened this burden by 38%.  “SARS-CoV-2 infectious viral particles detected in semen for up to 8 months after infection.” Outline of male body with depiction of virus particle near male pelvic area. rthm.com DOI: 10.1111/jsr.70371 DOI.ORG/ rthm.com doi.org/10.1016/j.bbi.2024.12.002

ALT study #4 study #1 Association of Prodromal Parkinson's Disease-Like Features in Long COVID With Dream-Enactment Behaviours study #1 Bei Huang, Eemil Partinen, Yaping Liu, et al. Journal of Sleep Research. 2026. Key Findings: This large-scale international study involving 11,261 participants found that long COVID is associated with a significantly higher burden of prodromal Parkinson's disease (PD)-like features, with long COVID participants showing a 73% increased risk compared to non-COVID-19 individuals. Notably, the emergence or worsening of dream-enactment behaviors (DEBs) further heightened this burden by 38%.  “SARS-CoV-2 infectious viral particles detected in semen for up to 8 months after infection.” Outline of male body with depiction of virus particle near male pelvic area. rthm.com DOI: 10.1111/jsr.70371 DOI.ORG/ rthm.com doi.org/10.1016/j.bbi.2024.12.002

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study #5 Prior SGLT2 Inhibitor and Metformin Use and Risk of Long COVID in Type 2 Diabetes: A Nationwide Population-Based Cohort Study The study finds that metformin use in patients with type 2 diabetes mellitus (T2DM) is associated with a lower risk of composite post-acute COVID-19 sequelae (PASC) and symptoms, while SGLT2 inhibitors (SGLT2i) specifically reduce the risk of neurological outcomes, including cognitive impairment and fatigue. Notably, patients using both metformin and SGLT2i exhibited an additive protective effect against these complications. The findings suggest that these antidiabetic medications may provide significant protective benefits beyond glycemic control in the context of Long COVID. DOI: 10.1007/s40121-026-01362-z

ALT study #5 Prior SGLT2 Inhibitor and Metformin Use and Risk of Long COVID in Type 2 Diabetes: A Nationwide Population-Based Cohort Study The study finds that metformin use in patients with type 2 diabetes mellitus (T2DM) is associated with a lower risk of composite post-acute COVID-19 sequelae (PASC) and symptoms, while SGLT2 inhibitors (SGLT2i) specifically reduce the risk of neurological outcomes, including cognitive impairment and fatigue. Notably, patients using both metformin and SGLT2i exhibited an additive protective effect against these complications. The findings suggest that these antidiabetic medications may provide significant protective benefits beyond glycemic control in the context of Long COVID. DOI: 10.1007/s40121-026-01362-z
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Patient-Led Research Collaborative (@patientled) and RTHM Clinic recently released the Long COVID Treatment Guide to support more informed conversations between patients and their clinicians. The guide covers over 30 different treatments. Today, we’re highlighting GLP-1 receptor agonists, including tirzepatide and semaglutide, which are included as an emerging therapy and may be especially relevant for people with Long COVID who experience MCAS, fatigue, cognitive impairment, gastrointestinal issues, pain, headaches, autonomic symptoms, and food intolerances. GLP-1 receptor agonists should be discussed with a qualified clinician to determine whether they are appropriate for an individual case. This includes reviewing risks, contraindications, drug interactions, allergies, and potential side effects. The guide also notes that nausea and constipation are common because these medications slow gastric emptying and gastrointestinal motility. Download the guide here: ow.ly/92EP50ZOpU4
Cover page titled GLP-1 Receptor Agonists from the Long COVID Treatment Guide by rthm Patient-Led Research Collaborative.

ALT Cover page titled GLP-1 Receptor Agonists from the Long COVID Treatment Guide by rthm Patient-Led Research Collaborative.

List of symptoms and conditions like MCAS, fatigue, cognitive impairment, and hypertension that a treatment is especially helpful for.

ALT List of symptoms and conditions like MCAS, fatigue, cognitive impairment, and hypertension that a treatment is especially helpful for.

Summary of a 2025 case series showing GLP-1s improved symptoms in 89% of MCAS patients with Long COVID, with manageable side effects.

ALT Summary of a 2025 case series showing GLP-1s improved symptoms in 89% of MCAS patients with Long COVID, with manageable side effects.

Summary text discussing a case study on POTS improvement with semaglutide and ongoing tirzepatide trial for Long COVID.

ALT Summary text discussing a case study on POTS improvement with semaglutide and ongoing tirzepatide trial for Long COVID.

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PEM can look different from person to person, and treatment may depend on a person’s specific triggers and underlying clinical picture. In this clip, Dr. Jennifer Curtin (@jencurtinmd) discusses how she approaches cognitive versus physical PEM, and why treatment often needs to be individualized. She shares strategies she has used in select patients, including IV saline, high-dose vitamin B1, LDN, injectable NAD, oxaloacetate, intranasal cromolyn, supplemental oxygen, medications that target autonomic symptoms, and devices intended to support cognitive tolerance. She also explains how factors such as dysautonomia, MCAS, and hypercoagulability may influence which approaches are considered. Join Dr. David Putrino, Dr. Lucinda Bateman, Dr. Jennifer Curtin, and moderator Charlie McCone for the full How to Manage and Treat Post-Exertional Malaise (PEM) webinar. Watch the full webinar recording on YouTube: piped.video/Na5znc92ylY
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Mitochondrial dysfunction is one area of growing interest in research on Long COVID and ME/CFS. In this clip, Dr. David Putrino from the @PutrinoLab shares emerging work on mitochondrial transplantation, an experimental approach that involves extracting, expanding, and infusing mitochondria in an effort to support mitochondrial function and cellular energy production. He discusses the early progress of this work, including its initial use in a patient outside of Long COVID and ME/CFS, and efforts underway to move toward a clinical trial in these patient populations. Join Dr. David Putrino, Dr. Lucinda Bateman, Dr. Jennifer Curtin, and moderator Charlie McCone for the full How to Manage and Treat Post-Exertional Malaise (PEM) webinar. Watch the full webinar on our YouTube channel: piped.video/@RTHM_Health
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