♾️BREAKTHROUGH: Researchers took cells from an 80-year-old and turned them into neural stem cells with a molecular age below 20. Stem cell therapies are a major key in the quest for immortality. It was once feared that we would need to collect our stem cells at birth to get maximum benefits from therapies. But now we are figuring out how to create our own personalised stem cells... even at ages over 80! The procedure could look something like: 1. Take ordinary cells from your blood or skin. 2. Reset them into young pluripotent cells. 3. Sequence them and remove dangerous clones. 4. Correct damaging mutations where necessary. 5. manufacture the exact replacement cells required. 6. Transplant them to rebuild ageing blood, immune tissue, cartilage, retina, heart muscle or damaged organs. In this particular study, they reprogrammed blood-cell precursors from donors aged all the way to 101 into neural stem cells, erasing most of their molecular signs of ageing. And the study is going wider than focusing only stem cell production. They are observing the process of the aged cell's transformation, in hopes to uncover mysteries of the rejuvenation process. Somewhere in the series of processes could hold the key to halting the aging of cells altogether. We are right on the doorstep of entering an incredible new era of health longevity.

Scientists found a single gene that extended median lifespan in old mice by 14% and slowed the progression of frailty by 44%. SRSF1 also pushed old human cells towards a younger state without wiping their identity. This is actual lifespan extension, not another ageing clock.

A gene variant found in people who lived past 100 is now being tested in old dogs 🐶 Genflow reports a 1.08-year drop on an ageing clock in its low-dose group after six months.