We use neuronal cell biology to study axon regeneration in the CNS, identifying and testing new therapies for eye disease and spinal cord injury.

London, England
Ravi Chidambaram, Kamal Kumar, Susan Ferro-Novick et al. @UCSanDiego identify peripheral tubule junctions as a site where RTN3L functions in ER-#autophagy. The Parkinson’s disease kinase, PINK1, regulates formation of these tubule junctions. hubs.la/Q02YwVFC0 #ER_literature
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Microscopy reveals how a lipid in the cell membrane called PI(4,5)P2 controls the activity of an important receptor that relays signals in to cells. elifesciences.org/digests/10…
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- Imaging interorganelle contacts at a glance - Reviews on machine learning, synchrotron X-ray imaging, fluorescence polarisation microscopy and imaging cell-cell junctions - An Editorial from @focalplane_jcs journals.biologists.com/jcs/…
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At the new Max-Planck-Zentrum für Physik und Medizin (#MPZPM), five Core Groups will conduct research to meet the most urgent medical challenges facing society. Get to know the group ›Neuronal Mechanics‹ led by Prof Kristian Franze 👉 bit.ly/MPZPM-Neuronal-Mechan…
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#Lipid synthesis drives cell invasion. Kieop Park et al. @SherwoodElegans lab @DukeU reveal that invasive cells need a rapid lipid production system and a dynamic prenylation process to breach basement membranes. hubs.la/Q02GL9bK0
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Super-resolution #microscopy: Insights into #mitochondria–#lysosome crosstalk in health and disease. A Viewpoint from Leisten, Woods, and Wong: hubs.la/Q02D49Nc0 In our Inter-Organelle Contacts collection: hubs.la/Q02D4dN_0
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A useful procedure for tissue clearing and immunolabeling on preserved brain specimens. elifesciences.org/articles/9…
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Happy to see the Special issue Patrick Caswell and I edited on Membrane Trafficking in Current Opinion in Cell Biology online. Pls check out reviews on your favorite organelles, trafficking, condensates, actin waves... more to appear. sciencedirect.com/special-is…
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Great news from our @BioelectronicsL @Cambridge_Uni! Our latest breakthrough in spinal cord neural interfacing is now featured in @ScienceAdvances. We've developed a flexible device that encircles the spinal cord, enabling 360-degree neural recording and stimulation. This innovative thin-film bioelectronic interface grants unprecedented access to previously unreachable areas of the spinal cord, opening new possibilities to restore lost neurological functions. Discover more about how we're unlocking the full potential of the spinal cord in our full study: science.org/doi/10.1126/scia… Kudos to all the authors: @WoodingtonBen #JiangLei @AlejCarnicer @AmparoGuemes @TobiasENaegele #SamHilton @SalimElHadwe #RikinTrivedi @GeorgeMalliaras #Neuroscience #Innovation #Neurosurgery #SpinalCordInjury #Neuroprosthetics #BCI #MedicalResearch @NIHRresearch @RCSnews @acmedsci @EPSRC @EANSonline50 @AANSNeuro @CNS_Update
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Studying on Mitochondrial Functions in Neuroscience? Consider submitting your work to this Scientific Reports Collection I am co-editing with Prof. Han: "Mitochondrial dysfunction in neurodegenerative disorders Collection". Contact me if needed! nature.com/collections/aheji…
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Excited to share our paper by @DePaceRaffa @SaikatSls et al. showing that BORC-dependent transport of lysosomal vesicles into the axon is crucial for the axonal movement of a large cohort of mRNAs, mainly those encoding ribosomal and mitochondrial proteins nature.com/articles/s41593-0…
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Truly a "miracle" of science and public health. Millions are alive and walking today thanks to the polio vaccines. Grateful to Jonas Salk, Albert Sabin, and other pioneers in this field.
69 years ago #Today, Jonas Salk's polio vaccine was declared safe and successful, Salk was hailed as a "miracle worker" and the day almost became a U.S. national holiday.
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A pioneer in neuroscience, #umiami researcher Dr. Mary Bunge leaves a legacy on the path to curing paralysis. bit.ly/3wt3unJ @umiamimedicine
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Sirtuin3 ensures the metabolic plasticity of neurotransmission during glucose deprivation, say Anupama Tiwari, Ghazaleh Ashrafi @GhazalEYN and colleagues @WUSTLCellBio: bit.ly/3R92zAt @MarionAlya #Neuroscience #Metabolism #CellMetabolism #Organelles
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CO2, regulation and metabolism. @NicoleMFenton @BrownLabUNSW explore a #PLOSBiology study that provides the first link between #CarbonDioxide and the master transcriptional regulator of #cholesterol homeostasis. Paper: plos.io/3QEDs7f Primer: plos.io/46sLSV2
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