A group of chemical biologists at Imperial College London and the Francis Crick Institute
London
- Tweets 208
- Following 157
- Followers 2,038
- Likes 158
Ed Tate retweeted
Congratulations to Myricx Bio, a spinout co-founded by @TateScience based on research from @impchemistry & @TheCrick, which has raised £90m to move its novel cancer treatment into clinical development 👏 @RoySocChem #startup #cancer @imperialcollege
imperial.ac.uk/news/254635/i…
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Join our group as a Research Associate in Cancer Drug Discovery! See below for more on the medicinal chemistry challenges of designing novel covalent ligand series against traditionally intractable cancer drug targets imperial.ac.uk/jobs/descript…
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We're looking for a Technical Specialist in Mass Spectrometry to join the Chemistry Department at Imperial's White City campus. Read about how the role can help us get the most of our state-of-the -art instruments tinyurl.com/4kuurhpm
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Apply for a fully funded 4 year PhD studentship researching antibody-drug conjugates (ADCs) in collaboration with AstraZeneca. Shortlisting closes by March 23rd! findaphd.com/phds/project/an…
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Our new research on UV-light activated probes that can discover novel protein-protein interactions in @ChemicalScience tinyurl.com/26pyzrau
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Ed Tate retweeted
Funded by @ERC_Research, a new study from the lab out in @NatureComms discovers how a tiny protein called CD59 provides a last line of defence against a giant b-barrel immune pore. rdcu.be/c5L1L. @EmmaCouves @TomasVoisin @scott_d_gardner @TateScience @pstansfeld
ALT CD59 (pink) captures and redirects pore-forming b-hairpins of MAC assembly intermediates (blue).
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Celebrating #internationaldaywomenandgirlsinscience 2023 @TateScience @impchemistry and @TheCrick ! Very proud to work with this amazing group of scientists!
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Apply now! 2 fully funded 4yr PhD studentships for Oct 2023 - new deubiquitinase (DUB) probes & approaches to discover & drug protein allosteric sites - shorlisting closes mid-Feb!
imperial.ac.uk/chemical-biol…
@impchemistry @ubiquigent @lwalport @TheCrick @laboratorychild @s_yaliraki
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Congratulations to @TateScience members Leran, Dan, @Elena_De_Vita, @scottlovell34, @AndreaGoyaG, and the teams of Aubrey Miller @DrugDiscov_DKFZ, Svend Kjaer @TheCrick and Janosch Hennig @embl on their report @J_A_C_S of a potent and selective probe for KLK6!
A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion @TateScience @imperialcollege #ActivityBased #PancreaticCancer #Cell #Invasion
pubs.acs.org/doi/10.1021/jac…
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Ed Tate retweeted
Computational resources provided by @hecbiosim allowed us to see how the lipid environment could tip the balance between CD59 as an immune regulator or host receptor hijacked by bacterial virulence factors.
Excited to share new work from the lab explaining how human cells are protected from MAC pores during an immune response. Big thanks to @ERC_Research and @eBIC_Diamond for making this work possible! In collaboration with @TateScience and @pstansfeld biorxiv.org/content/10.1101/…
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Excited to announce CORe, proteome-wide in-cell site-directed mutagenesis screening @NatureMicrobiol! Deconvolute role of any ligandable site, reactive amino acid, PTM, and more, at scale, at endogenous abundance! Fantastic collaboration with @laboratorychild @henrybenns
Out now, drug discovery for apicomplexans👉CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery @laboratorychild
@henrybenns
@TateScience
@imperialcollege nature.com/articles/s41564-0…
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Fantastic and unique long-term position for synthetic medicinal chemists interested in research supervision, #training, #education and #innovation in #medicinalchemistry and #drugdiscovery. Based in @TateScience @imperialcollege White City Campus. imperial.ac.uk/jobs/descript…
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Three new positions available @TateScience @imperialcollege and @TheCrick, deadline 9th Nov, start early 2023 - please retweet!
Postdoc positions in cell and chemical biology:
jobs.ac.uk/job/CTX333/resear…
jobs.ac.uk/job/CTX300/resear…
Chemical Biology Technician:
jobs.ac.uk/job/CTX316/chemic…
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Fantastic video featuring Anna Barnard imperial.ac.uk/the-barnard-g… raising awareness of what we need to do now to stop #AntimicrobialResistance devastating future healthcare, briefly also featuring @Dr_Ravi_Singh
bbc.co.uk/ideas/videos/i-los…
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Congratulations to @TateScience scientists who created our stand on Innovative Therapies @ExRdFestival 2022! @Elena_De_Vita @Michalska_P_ @ChemGray @Dr_Ravi_Singh Folake Tianze Fangyuan Edward Lame Qisi Haozhe Josephine and more! @WorldwideCancer @impchemistry @TheCrick
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Many congratulations to @Elena_De_Vita, highly commended finalist in the L'Oreal-UNESCO Rising Talents Life Sciences Award!
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Apply now! Medicinal chemistry postdoc position @TateScience - join our team @imperialcollege and @TheCrick to work on novel & challenging cancer drug targets, supported by chemical biology and #CryoEM with @OxfordStrubi
#postdoc #postdocposition @CR_UK jobs.ac.uk/job/CPU080/resear…
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Interested in PROTACs and/or ADCs? Join us to work on ADC-PROTACs! We have a new 4-year MRes/PhD studentship available @TateScience @imperialcollege starting October 2022, in collaboration with @adctherapeutics - apply now! findaphd.com/phds/project/un…
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Congratulations to @Daniel_Lucy1 from our lab who was a finalist at the 2022 @STEM4Brit competition, presenting his work on chemical probe-guided surgery.
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Great to celebrate on Thursday with @TateScience #PhD alumni visiting from the UK and around the world for @imperialcollege #graduation - #Congratulations Miha, Jasmine, Kwang, Theo, Cass, Andrea, Ryan, Kate and Jessica, so proud of what you have all gone on to achieve!
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