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How much can a fundus photograph tell you about biological aging? Researchers at Seoul National University developed a deep-learning model which may serve as a scalable, population-level characterization of biological aging. #Artificial Intelligence # Ophthalmology #DeepLearning
A study in Ethiopia found no difference in the prevalence of conjunctival Chlamydia trachomatis between double-dose azithromycin and intensified facial cleanliness and environmental improvement compared with standard SAFE interventions. Read more here: pubmed.ncbi.nlm.nih.gov/4216…
Three biologics walked into a uveitis trial…two were alike and one went home! Check out new @AJOphthalmology study comparing Adalimumab, Anakinra, and Tocilizumab for managing noninfectious uveitis
Could common anti-inflammatory medications help reduce the risk of DME and PDR in patients with T2DM? A recent study in @AAOjournal found that cetirizine, ibuprofen & prednisone were associated with reduced incidence of DME and PDR in adults with T2DM. pubmed.ncbi.nlm.nih.gov/4272…
QOW: A 42y F complains of increasing blurriness and redness in her right eye after getting NaOH drain cleaner in it. At the time of injury she rinsed her eye with tap water for 10 mins and has been using artificial tears since. She now has worse eye irritation.
Which of the following explains the primary mechanism of this patient’s injury?
A: Protein coagulation limiting injury
B: Saponification of cell membrane + liquefactive necrosis
C: Immune complex deposition in corneal stroma
D: Thermal injury
Correct Answer: B
Alkaline agents cause saponification, enabling quick penetration through the cornea and into deeper parts of ocular tissues. This can damage the stroma, cause limbal ischemia, and injure the trabecular meshwork causing haze, epi defects, and elevated IOP.
A new @BMJ_Ophth study suggests that greater sunlight exposure may be associated with increased POAG risk and faster RNFL thinning, particularly among individuals with higher genetic susceptibility. Read more at: pubmed.ncbi.nlm.nih.gov/4264….
Can circadian misalignment dry out your eyes? A new @SciReports cohort study demonstrates that circadian rhythm sleep disorders significantly increase the long-term risk of dry eye disease, highlighting a key clinical sleep-tear connection. Read more: pubmed.ncbi.nlm.nih.gov/4271…
The organisms behind post-cataract endophthalmitis are evolving. Over 23 years, coagulase-negative staphylococci decreased while E. faecalis increased. Cefuroxime & methicillin resistance rates also increased. Read more: ajo.com/article/S0002-9394(2…#Endophthalmitis@AJOphthalmology
How does musical instrument performance change IOP? An international team of researchers details their findings on the topic in a new paper published in Ophthalmology: pubmed.ncbi.nlm.nih.gov/4203… 🎷🎼
Blood spanning multiple retinal layers in an older patient with HTN is classic for a ruptured RAM- an acquired focal dilation of a retinal arteriole that can present through hemorrhage, exudation, or both.
Do neurodevelopmental and behavioral disorders raise pediatric eye disease risk? In 1.16 million matched pairs, amblyopia, strabismus, and myopia risks were 60%, 66%, and 55% higher; strabismus surgery was less common. Read more: pubmed.ncbi.nlm.nih.gov/4255…