@VanderbiltU lab focused on the molecular✂️ known as type II topoisomerases. Account is student run.

Nashville, TN
Our studies follow the publication of the results of a phase III trial using oral gepotidacin for uncomplicated urinary tract infections @GSKUS: doi.org/10.1016/S0140-6736(2… (2/3)
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@GSKUS also recently announced positive positive results of a phase III trial using gepotidacin for uncomplicated urogenital gonorrhea: tinyurl.com/gepogon (3/3)
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Microbe of the month: Pseudomonas aeruginosa dlvr.it/Sztxjm
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Happy to report our recent collaboration with the Mitton-Fry lab at @osu_pharmacy demonstrating that dioxane-linked amide NBTIs can induce both single- and double-stranded DNA breaks mediated by N. gonorrhoeae gyrase and topoisomerase IV @IJMS_MDPI tinyurl.com/OSUAB185
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Congratulations to our very own Jill Armenia who was selected as the @VandyBiochem Student of the Month! Oh...did we forget to mention that she also passed her qualifying exam a few weeks ago and is now a PhD CANDIDATE!
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There's a new doctor in the house! Everyone say hello to: Dr. Alexandria Oviatt! @topoisomeracer Congratulations on successfully defending your thesis! We're all so excited and proud of you!
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Alexandria (@topoisomeracer) is defending this Monday! Monday, March 14 10:30 am CST 512 LH or Zoom (DM for Zoom link)
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Introducing...[drumroll 🥁 please] Dr. Esha Dalvie 🎓 @kitty_catenenes Congratulations on successfully defending your thesis! We are so proud of you & can’t wait to watch you succeed in your postdoc at @ChemistryMIT
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It’s happening!
TODAY at 1 pm! Don't miss Esha Dalvie's (@kitty_catenenes) defense! Happening in PRB 206
Just 3 days until Esha (@kitty_catenenes ) defends! Monday, March 7 1 pm CST 206 PRB or Zoom (DM for Zoom link)
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Please mark you calendar for a special @VandyBiochem seminar! A colleague of Dr. Neil Osheroff (@Topo_Lab), Dr. Gabriel Frank (@bengurionu) presents "Determining the structure of the seminal biomineral/protein interface by cryo-EM” Tuesday, March 8, 11:00 pm CT, 618 Light Hall
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As if one defense weren’t enough, please join us for Alexandria’s (@topoisomeracer) defense in 3 weeks! In-person: 512 LH Zoom: DM for info
Dissertation Defense! Join us for Alexandria Oviatt (@topoisomeracer, Osheroff, @Topo_Lab), "A Tale of Two Poisons: Overcoming deleterious anticancer side effects and antibacterial resistance" March 14, 10:30 am, 512 Light Hall Contact patricia.l.mueller@vanderbilt.edu to Zoom!
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It’s time: Esha is defending in exactly 2 weeks! Come in person (206 PRB) or via Zoom (DM for link) to hear about her work.
Dissertation Defense! @VandyBiochem presents Esha Dalvie (@e_dalvie, @Topo_Lab), "Covalent Poisons and Catenation: The Effects of Natural Products and DNA Topology on Reactions Catalyzed by Type II Topoisomerases" March 7, 1 PM, 206 PRB Contact patricia.l.mueller@vanderbilt.edu
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Osheroff Lab retweeted
<2 weeks left to apply for Asst. Prof. positions in the Dept. of Biochemistry at Vanderbilt University. Great opportunity to establish a research program focused on molecular mechanisms of biological processes. apply.interfolio.com/94568 @VUBasicSciences @VandyBiochem Please RT
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My first first-author paper is up on bioRxiv! Feel incredibly grateful to all the help I've gotten along the way. Thanks @JamesMDewar @davidkcortez @Topo_Lab + my lovely Dewar lab members (@TKavlashvili @LillianVCampos )
Our first foray into bioRxiv! We're really surprised that these chemotherapeutics inhibit DNA replication in such different ways. Graduate student @sabrinadoessci1 did an amazing job. Incredibly grateful to collaborators in Neil Osheroff and @davidkcortez. 💊🛑🧬🐸
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Congrats, Sabrina!
Just won best poster at #EMBO DNA Topology meeting! @LillianVCampos showed great work as well. I feel really grateful and excited. Will hopefully share soon my project work in @Dewar_Lab, with collaboration with @davidkcortez and @Topo_Lab! 🐸🧬
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