The TriState SenNet Tissue Mapping Center is an NIH-funded group of researchers at Pitt, CMU, OSU, & URMC who study cellular senescence in heart & lung tissue.

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We love hosting CUSP students! If you're an undergraduate student interested in #senescence or #aging biology, this is the program for you. Applications for the 2025 cohort are open until January 25th. Learn more about the program from past students: piped.video/watch?v=kb1WmS3u…
The 2025 Consortium Undergraduate Student Program (CUSP) is recruiting! Join us for summer internships focused on senescence study in a variety of research sites across the U.S. More info and application at: sennetconsortium.org/interns…
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Dr. Birgit Schilling (@birgits61642917) of the @BuckInstitute will present at our TriState SenNet meeting on Wednesday, 11/15 at 4 p.m. She will talk about cellular #senescence and #aging & discuss our collaborative pilot project for @sennetresearch. Please join us! More below:
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Dr. Irfan Rahman of our @TriStateSenNet TMC has a new article, "Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization," in @NatureComms! Read more about his work in #IPF and #aging here: nature.com/articles/s41467-0…
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Congratulations to Dr. Irfan Rahman of our consortium and @UR_Med for his recent @SOToxicology Leading Edge in Basic Science and Career Achievement awards at #2023SOT! Read more about Dr. Rahman and his important research here: toxchange.toxicology.org/blo…
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@TriStateSenNet is looking for two undergraduate students to spend the summer as a paid intern in the labs of @m_konigshoff and @MR_AgingLab. Come join our exciting work in #aging and cellular #senescence! Check out the link below for more details 🔬
Our CUSP summer internships are now open! Deadline is March 1st! sennetconsortium.org/interns…
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We had a wonderful time at the TriState SenNet Conference with our teams from @PittDeptofMed @UR_Med @OSUWexMed @CMUCompBio last week. Can't wait to see everyone again! #TriStateTogether @sennetresearch @NIH_CommonFund
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We're hosting our first in-person meeting June 8th & 9th at the University of Pittsburgh! We're so excited to see everyone in person and on Zoom and to discuss the progress of our #senescence grant from @NIH_CommonFund. Stay tuned for conference updates! #TriStateTogether2022
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Congratulations to Dr. Mauricio Rojas (@colblackberrys @MR_AgingLab) and Dr. Melanie Koenigshoff (@m_konigshoff) of our TriState SenNet Consortium on being the authors of the #ATSMostCited2022!
Congratulations to the #ATSMostCited2022 AJRCMB authors for their paper “Applications and Approaches for Three-Dimensional Precision-Cut Lung Slices: Disease Modeling and Drug Discovery." Read it here:bit.ly/3yl7Dcc
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Check out this recent @ATSBlueEditor publication by our @PittDeptofMed & @PACCM_fellows TriState SenNet team members @morrisa1668 @JohnSembrat & Dr. Jonathan Alder!
Hot off the press in @ATSBlueEditor CD4+ T cell dysfunction in severe COVID19 disease is TNFa/TNFRI-dependent By @PACCM faculty Drs. Popescu, Snyder, Kitsios, Kass, Alder, Chen, Lendermon, Kilaru, Johnson, Pilewski, Morris, McVerry, Chen & McDyer atsjournals.org/doi/abs/10.1…
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Check out this recent review by Dr. Aditi Gurkar (@healthspan_AUG) of our TriState SenNet team on the connection between lipids and cellular #senescence in @FrontiersIn!
Lipids and cellular senescence- what is the connection? Check out our review! doi.org/10.3389/fphys.2022.7…
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Please join Dr. Toren Finkel, the Director of @AgingPitt and one of our TriState SenNet PIs, for a virtual @SFRBM seminar on Tuesday, March 29th at 12:00 p.m.!
Upcoming Virtual Seminar: Dr. Toren Finkel, MD, PhD, at @AgingPitt will discuss the underlying mechanisms and therapeutic potential of lysosomal stress on Tuesday, March 29 at 12:00 p.m. ET. Register here: conta.cc/3vTw6nJ
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Thank you again to Dr. Julián Chamucero (@ChamuceroJulian) of @MR_AgingLab and Dr. Gagandeep Kaur of @UR_Med for their presentations yesterday at our monthly TriState SenNet large group meeting!
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Congratulations to two of our TriState SenNet PIs, Dr. Melanie Koenigshoff (@m_konigshoff) of @PACCM and Dr. Irfan Rahman of @UR_Med, for their @atscommunity 2022 Recognition Awards for Scientific Accomplishments!
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Congratulations to Dr. Qin Ma (@QinMaBMBL) of our TriState SenNet Data Analysis Core for another new grant!
Pelotonia Idea Grant awardees Drs. Catherine Chung, Walter Hanel, Qin Ma, (@QinMaBMBL), & Anna Vilgelm (@avilgelm) study whether non-malignant cells of the skin protect malignant T cells from therapies & therefore should be targeted to overcome resistance. bit.ly/3I3DY9u
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Congratulations to Dr. Dongmei Li @dongmeiliur of our TriState SenNet Data Analysis Core on her recent paper!
Our newly published paper: doi.org/10.34133/2022/975840… The COVID-19 Pandemic and Mental Health Concerns on Twitter in the United States
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Check out this recent publication on #singlecell #transcriptomics by Dr. Ziv Bar-Joseph of our TriState SenNet team!
Temporal modelling using single-cell transcriptomics go.nature.com/35FdsoB #Review by Jun Ding, Nadav Sharon & Ziv Bar-Joseph @cusm_muhc @TechnionLive @CarnegieMellon @CMUCompBio @CmuScience @mldcmu Free to read here: rdcu.be/cF8H5 #SharedIt
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Congratulations to @QinMaBMBL of our TriState SenNet Data Analysis Core on his new grant!
Pelotonia Idea Grant recipients Drs. William Carson (@CarsonLabOSU), Qin Ma (@QinMaBMBL), and Gang Xin (@GangXin1) lead a study that will inform the development of promising treatments to restore responsiveness to PD-1 blockade for breast cancer patients. bit.ly/3I3DY9u
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Check out this new paper from Dr. Aditi Gurkar @healthspan_AUG in @ScienceAdvances! Dr. Gurkar is part of our TriState SenNet team in Pittsburgh @AgingPitt. Congratulations!
Super excited to share our paper out in @ScienceAdvances this week! This story led by talented @shruthi262 uncovers how persistent DNA damage alters the metabolic-epigenetic-immune axis to drive AGING. science.org/doi/10.1126/scia…
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Thank you again to @KambezBenam of @PACCM for his presentation and to @healthspan_AUG of @AgingPitt and Dr. Jonathan Alder of @PACCM for their presentation at our monthly TriState SenNet large group meeting last week!
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