Account of the Chromatin, cancer and the ubiquitin system lab, based in the CBM. Focus on DNA replication dynamics, ubiquitin, SUMO and cancer.
CBM, CSIC-UAM - Madrid
- Tweets 47
- Following 53
- Followers 79
- Likes 31
Emilio Lecona's Lab retweeted
¿Te interesa la relación entre cromatina, epigenética y cáncer? 🧬
El 28/9 acogemos en el CBM el II Chromatin alterations in cancer development symposium y ¡aún quedan plazas!
🎟️ Inscripción hasta el 10 de septiembre:
cbm.uam.es/index.php/events/…
@UbiSystemLab @AnaOrtegaMolin1
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Sigue abierta la inscripción para el Simposio, tanto para asistir como para presentar un póster o una charla corta. ¡Os esperamos!
📢 Ya está abierto el plazo de inscripción para el II Chromatin Alterations in Cancer Development Symposium, que será el 28 de septiembre en el CBM. Organizado por nuestros investigadores @AnaOrtegaMolin1 y @Emlecona.
🗓️ Deadline para inscribirse: 9/9/26
cbm.uam.es/index.php/events/…
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Congrats @rodrimartinr on your great thesis defense and thanks to María Villa, AnnaMaria Ruggiano and Jim Sutherland for their work as Thesis Committee. Rodrigo is the first PhD from the lab and we cannot be prouder of his great work. All the best in your future career!
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It was a great honor to host Keith Caldecott at the @CBM_CSIC_UAM
Thanks for a very inspiring talk.
Hemos tenido el placer de recibir a Keith Caldecott en el CBM. Su charla abordó el papel de la actividad PARP en la reparación de roturas de ADN y su impacto en enfermedad humana, y los mecanismos clave para mantener la estabilidad del genoma y entender patologías asociadas.
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Fresh from the oven! Our new perspectives article where we discuss the interplay between lagging strand DNA replication and the replication stress response.
An updated view on lagging strand DNA replication: implications for the replication stress response tandfonline.com/doi/full/10.…
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There is still time, contact us if you are interested
We are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva 2025 call, to join our lab at the @CBM_CSIC_UAM to work on the interplay between the ubiquitin pathway, DNA replication and the replication stress response.
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Congrats Alicia on the best poster prize in the PhD & Postdoc Annual Meeting @CBM_CSIC_UAM
Very proud of you! Many more successes to come!
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Emilio Lecona's Lab retweeted
We are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva 2025 call, to join our lab at the @CBM_CSIC_UAM to work on the interplay between the ubiquitin pathway, DNA replication and the replication stress response.
Aprobada la convocatoria Juan de la Cierva 2025 (#JDC2025) para fomentar la incorporación de jóvenes doctores/as y completar su formación postdoctoral en centros de I+D.
▶️500 ayudas
💵60 M€ (+21,7 M€ que 2024)
📅Plazo: 25 nov-10/17 dic 2025
📰aei.gob.es/noticias/agencia-…
#FSE+
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We are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva 2025 call, to join our lab at the @CBM_CSIC_UAM to work on the interplay between the ubiquitin pathway, DNA replication and the replication stress response.
Aprobada la convocatoria Juan de la Cierva 2025 (#JDC2025) para fomentar la incorporación de jóvenes doctores/as y completar su formación postdoctoral en centros de I+D.
▶️500 ayudas
💵60 M€ (+21,7 M€ que 2024)
📅Plazo: 25 nov-10/17 dic 2025
📰aei.gob.es/noticias/agencia-…
#FSE+
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Emilio Lecona's Lab retweeted
Postdoctoral Position in "Molecular Mechanisms
of Childhood Leukemia Development" at CBM, Madrid @CBM_CSIC_UAM
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Emilio Lecona's Lab retweeted
🎉👏🏅¡Enhorabuena a los galardonados con los Premios a Jóvenes Investigadores Fundación BBVA-@SEBBM_es!
Consulta la lista de los premiados:
📰bbva.info/42aw8a4
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Very proud of @rodrimartinr showing his work his awesome work.
Regulation of DNA replication and the replication stress response by ubiquitin and VCP/p97 por @rodrimartinr de @UbiSystemLab @CBM_CSIC_UAM #47congresoSEBBM
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Emilio Lecona's Lab retweeted
Another exciting research article from a member of the #RepliFate network!
The @altmeyerlab identified the CNOT1-CCR4-NOT complex as a multi-level suppressor of the 53BP1-p53-p21 signaling axis.
Check out their findings here: doi.org/10.1016/j.celrep.202…
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Still looking! Please spread the word.
We are looking for a candidate to apply to a #MSCA Postdoctoral Fellowship in our lab in the @CBM_CSIC_UAM, working on the connections between DNA replication dynamics, replication stress and genomic instability in cáncer. Contact us if you are interested and please retweet.
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We are looking for a candidate to apply to a #MSCA Postdoctoral Fellowship in our lab in the @CBM_CSIC_UAM, working on the connections between DNA replication dynamics, replication stress and genomic instability in cáncer. Contact us if you are interested and please retweet.
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Emilio Lecona's Lab retweeted
Muchas gracias por destacar nuestro trabajo en el @UbiSystemLab liderado por @rodrimartinr y en colaboración con @SaraRodriguezAc en el @JMendez_DNA lab.
Avance clave desde el @CBM_CSIC_UAM , donde trabajó Margarita Salas: descubren un mecanismo que regula cómo se copia el ADN y evita errores durante la replicación.
#Ciencia #CBM #Replicacion #ADN
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Fresh from the oven! Ever wondered how cells keep ATR activation controlled during normal DNA replication? Our last paper in @NatureComms shows that they do it by extracting POLA/PRIM from chromatin using VCP/p97! Still curious? Take a look...🧵🧵🧬🧬
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So, to sum up: VCP/p97 ➡️ POLA/PRIM on chromatin ➡️ priming ➡️ basal RSR activation! This work was led by @Emlecona from @CBM_CSIC_UAM in collaboration with @JMendez_DNA from @CNIOStopCancer. Want to dive a little bit more in our work? Click this link! rdcu.be/eu1yo
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Huge thanks to all people involved, @SMOA_CBM and flow cytometry facilities from @CNIOStopCancer and @CBM_CSIC_UAM.
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