Biophysicist, Soft Matter Enthusiast, Associate Professor at Georgia Tech. Views are my own.
Atlanta, GA
Based in United States
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This was a wonderful collaboration with @siulung2005 @KAMacGillivray and Brian Hammer.
But this paper was possible thanks to the efforts of a truly incredible PHD student, @pabravoc who did experiments, simulations, theory, graphic design, and more to tell this exciting story.
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How do biofilms grow vertically? Find out in our paper, out now:
pnas.org/doi/10.1073/pnas.22…
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Let's do it! Maybe we can get someone to build a hydrodynamic treadmill, too.
nature.com/articles/s41592-0…
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This work was done in collaboration with @briankhammer, @siulung2005, and @KAMacGillivray. We are so fortunate to have such great collaborators at @GTSciences and @GaTechMicrobes, without whom this work would not be possible!
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OK, really this work is studying how biofilms grow vertically. Here I’ll explain what the problems were, what we found, and how we can measure topography with nanometer resolution. (And in this case “we” really means @pabravoc who did incredible work here!)
ALT Biofilm topography at different times
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Just in time for the start of the school year we have a new print studying how biofilms grow up:
biorxiv.org/content/10.1101/…
ALT Topographies of different microbes
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Very interesting idea. We definitely hope that this approach can help with many different problems by offering a framework to actually quantify just how randomly cells are organized. Especially if you have an organism in mind, I'd love to hear more!
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For anyone interested in hearing more, @thomas_day_ will be giving an invited talk at the APS March Meeting this year: meetings.aps.org/Meeting/MAR…
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It's a Turing instability! As ridges get taller they capture more sand and block sand from reaching adjacent troughs - an emergent activator-inhibitor interaction. (Though I'll note, while this argument makes sense, I've never seen data validating it.)
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I really enjoyed reading this paper, and this thread!
How and why can division of labour evolve without efficiency benefits from individual specialisation? Our new paper at @eLife with Hadleigh Frost, @PapilioMing, and @StuWest8. A thread:(1/10)
elifesciences.org/articles/7…
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This sounds fascinating @ricard_sole ! Is there any chance a recording is available?
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It was a blast working on this project with @mmatherne6 @drdavidhu @Gabi_Steinbach
The soft matter physics of how bees transport pollen is rich, fascinating, and fun!
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As @wc_ratcliff and @dahaj1897 described, this is difficult to do. We (really @thomas_day_ and Dr. Shane Jacobeen) tried it any way. Those experiments produced some interesting results---which we still do not understand!
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