Adam Widman@adamjwidman

Physician-scientist @sloan_kettering. Liquid biopsy, AI and cancer genomics

 New York, NY
mskcc.org/research-areas/res…
Joined January 2022
13 Photos and videos
MRD-EDGE is out today in @NatureMedicine! Thrilled to see this in print when the future for #ctdna in plasma whole genome sequencing is brighter than ever.
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How do you scale up liquid biopsy for use in routine cancer monitoring? Combine plasma-only ultrasensitive detection with cheap sequencing and a simple lab workflow. A big thanks to @AlexandrePCheng for pushing this work over the finish line! Stay tuned and more to come
Alexandre Pellan Cheng@AlexandrePCheng
11 Apr 2025
What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau_lab Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb
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The integration of duplex sequencing with cost-effective Ultima sequencing enhances the accuracy of whole-genome circulating cell-free DNA profiling. @landau_lab @AlexandrePCheng nature.com/articles/s41592-0…
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Thanks @amanda_fbj and @ClausLindbjerg for leading here! Very excited to see this out in print
Amanda Frydendahl Boll Johansen@amanda_fbj
20 Jan 2025
💡New paper out in @MolOncology demonstrating detection of #ctDNA in patients with #colorectal #adenomas by #WGS (MRD-EDGE)! Thanks for great collab @landau_lab & @adamjwidman! @ClausLindbjerg @JesperNors @GaardNadia @TennaVesterman @moma_dk @AUHdk febs.onlinelibrary.wiley.com…
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Congrats Nico and Will and Bishoy and team!
Nicolas Robine@notSoJunkDNA
9 Oct 2024
Special nugget for my genomics friends in today's paper: Read everything but don't miss Extended Data Fig. 8, where @willbfx assembled a CCND1-ecDNA from @nanopore reads!
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Congrats to Josh and team!
Josh Schiffman@jsschiffman
24 Sep 2024
Excited to share "Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution", from an amazing collaboration with @landau_lab @ar_davino @TamaraPrietoF @hara_toshiro @MarioSuva! A tweetorial, or Xplanation ... nature.com/articles/s41588-0…
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#NESTTrial 🪺 responses to date.🙌🏾 What’s particularly of note is the deepening of the responses with longer time to brew 🫖. The pattern🌊 and lack of recurrence speaks to curative potential of immunotherapy for both MSS and MSI-High tumors. #CRCSM @myESMO #ESMOGI24 @OncoAlert
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parts per million -> parts per billion -> parts per trillion? how low can we go with ctDNA detection in the era of dirt cheap whole genomes ?? .. momentous milestone by @adamjwidman @landau_lab & team👇👇👇
Adam Widman@adamjwidman
14 Jun 2024
MRD-EDGE is out today in @NatureMedicine! Thrilled to see this in print when the future for #ctdna in plasma whole genome sequencing is brighter than ever.
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RT @EricTopol: A major problem with cell-free tumor DNA to detect cancer (Liquid biopsy) is its very low quantity. Today @NatureMedicine us…
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MRD-EDGE is out today in @NatureMedicine! Thrilled to see this in print when the future for #ctdna in plasma whole genome sequencing is brighter than ever.
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more replies
In the future the ability to monitor tumor burden after every intervention will completely transform cancer care. Let’s build the tools to get there!
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Open link- rdcu.be/dKNOx
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An artificial intelligence-powered method for detecting tumor DNA in blood has shown unprecedented sensitivity in predicting cancer recurrence, says a team led by Dr. Dan Landau (@landau_lab) and researchers at @nygenome and @MSKCancerCenter. bit.ly/45pXCJ3
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