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Sure, AI might destroy our civilization, but for one brief moment, it produced this greatness.
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In this vein, it's also going to destroy SaaS because now people can easily cancel their forgotten subscriptions
The chief economist at Apollo is warning that mass adoption of AI agents could trigger a bank run as they optimize user investments. Gary Gensler spent his last few years as SEC chair warning that the exact same problem will hit the markets: the pursuit of algorithmic perfection at scale destroys system stability. Personal-finance agents making simultaneous optimal decisions could potentially cause a massive flash crash.
Agent acausal coordination, with no messages passed between them, will show up in a lot of places. Markets will get the big headlines, but huge numbers of clever advisors making very similar choices will impact all of human society. Capability gains make this worse, not better. The smarter the agents, the narrower the optimal path; and knowing that other agents see that exact same path lets them move together without talking to each other. Agents do not need to collude to act in unison. Thus, they break no human laws by doing so. Human laws were not written for this. They were not written for a lot of what is coming, and it is about to start happening very fast.
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But perhaps the most fascinating one to watch will be the ballooning American health care system, which will struggle under the merciless weight of bots filing claims nytimes.com/2026/09/24/busin…
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Well, actually, you can decide to start a "prescribed" forest fire on the first hot day after a week of cold and fog when the sun didn't come out. And you don't need to notify SF residents
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This is one of the coolest real-world applications of AI I've seen
18 months ago, I went all in on studying biology. I started by building a lab in my apartment (worms!) and later joined one at UCSF.
Meanwhile, models were making advances in the virtual world, but in the lab — they fell short.
We started C5R to fix this. See more below!
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In 12 weeks, we built a research facility that is run entirely by AI.
AI designs, executes, and observes experiments end-to-end across biology, chemistry, and materials science.
We’re introducing SciUniverse: a benchmark that measures AI’s ability to do real-world scientific research.
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Gen Z doesn't rent; it sublets. forbes.com/sites/ianshepherd… @snagsublets is the housing voice of a generation.
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Alexia Bonatsos retweeted
The whole world wants a Gov Graph. In two days, we've gotten requests for 43 cities, 30 states, and 57 countries.
This will become the default view of government, and eventually we'll wonder why we ever did it differently.
Introducing the US Gov Graph - a complete map of the people and positions of power in the federal government.
To fix our institutions we must understand how they work, so we are using AI to model and monitor every government in America. This is Palantir for The People.
Check it out here: graph.civlab.org/us
We exist to set the conditions for an era of civic excellence unmatched since the Founding. We will need nothing less to navigate the age of AI.
I'm looking for exceptional engineers and designers to work with me in San Francisco. If that's you, inquire here: tally.so/r/KY97RK. Self-governing civilization is counting on you.
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Alexia Bonatsos retweeted
Michael is a super smart guy and this is a great project. If you feel powerless about politics, but want to do something about, you should double click on this!
Introducing the US Gov Graph - a complete map of the people and positions of power in the federal government.
To fix our institutions we must understand how they work, so we are using AI to model and monitor every government in America. This is Palantir for The People.
Check it out here: graph.civlab.org/us
We exist to set the conditions for an era of civic excellence unmatched since the Founding. We will need nothing less to navigate the age of AI.
I'm looking for exceptional engineers and designers to work with me in San Francisco. If that's you, inquire here: tally.so/r/KY97RK. Self-governing civilization is counting on you.
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Alexia Bonatsos retweeted
The @getclearspace Family Membership will be a game changer for any parent who wants to help their kids learn to use their phones and the internet in a way that helps them rather than hurts them.
Check it out: clearspace.org/application
Screen time wasn’t a thing when I was a kid.
We had smartphones, we had social media, but the landscape was new and the dangers were hidden.
In 2023 during @ycombinator we launched Clearspace Self Control which has saved more than a million people from their phones.
In 2024 I became a Dad. And we started dreaming about what it would look like to give kids a childhood with less screen time.
We discovered that the key was to make it easier for parents to teach their kids the life skill of screen time - more transparency, more trust. Common reference points and a reliable foundation for meaningful conversations.
We made checking in and setting reasonable boundaries as easy as sending a text to a babysitter.
The Clearspace Family membership is officially open for new applicants.
clearspace.org/apply
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This is Interact's dominant strategy
One of the crazier facts about venture is that it seems consistently possible to build a small community of college-aged kids that is incredibly talent dense, e.g.:
- Thiel Fellows (ETH, Figma, I think Cognition)
- KP Fellows (Opensea, also Figma)
- Dorm Room Fund (Cursor)
- Prod (Mercor, Etched, also Cursor)
- Neo Scholars (Cog, also Cursor)
Other than Neo (@neo) though, this hasn't really become anyone's dominant strategy.
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Alexia Bonatsos retweeted
let me be more specific because Interact is elusive to many
Interact members have founded: Etched, Graphite, Figma, Cognition, Figma, Scale, Socket, Modal
Also some of the best operators. Start asking around and you'll see for yourself... they're everywhere!
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Alexia Bonatsos retweeted
Screen time wasn’t a thing when I was a kid.
We had smartphones, we had social media, but the landscape was new and the dangers were hidden.
In 2023 during @ycombinator we launched Clearspace Self Control which has saved more than a million people from their phones.
In 2024 I became a Dad. And we started dreaming about what it would look like to give kids a childhood with less screen time.
We discovered that the key was to make it easier for parents to teach their kids the life skill of screen time - more transparency, more trust. Common reference points and a reliable foundation for meaningful conversations.
We made checking in and setting reasonable boundaries as easy as sending a text to a babysitter.
The Clearspace Family membership is officially open for new applicants.
clearspace.org/apply
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Alexia Bonatsos retweeted
Introducing the US Gov Graph - a complete map of the people and positions of power in the federal government.
To fix our institutions we must understand how they work, so we are using AI to model and monitor every government in America. This is Palantir for The People.
Check it out here: graph.civlab.org/us
We exist to set the conditions for an era of civic excellence unmatched since the Founding. We will need nothing less to navigate the age of AI.
I'm looking for exceptional engineers and designers to work with me in San Francisco. If that's you, inquire here: tally.so/r/KY97RK. Self-governing civilization is counting on you.
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