And we are off! 10th Annual @MIPS_DDB student symposium. So excited to celebrate all the amazing research happening in our faculty. @HRM_MIPS @MIPS_Australia
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First speaker Felix shares his work looking to determine the structure of the P2X1 Receptor as a target for male contraception. @MIPS_DDB
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Next up we have Ahlam discussing her working looking at TCDA as a marker of hepatocellular carcinoma. @MIPS_DDB @HRM_MIPS
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Final speaker for our morning session is @JoeWake7 who shared his work exploring different cardiac GPCRs as a potential for cardiac fibrosis, a common hallmark of cardiovascular diseases @MIPS_DDB @laurentmay
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Thank you to @NatalieTrevaski, @ppelvazhao, @Thal_DM, Kevin Nay, @helenaqcx and @PatrickMSexton1 for sharing their experiences and sharing some advice on travelling after your PhD @MIPS_DDB @HRM_MIPS
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Kicking off our middle session is @Theodor95859205 sharing some insights into the structure the PAC1R coupled to Gq.@MIPS_DDB
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Next up for the day is @micc_mah discussing all things intestinal lymph and ceramides. @DrSaramide @MIPS_DDB
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Next up is my #teamhscr teammate @NS_Mahdavian who is discussing her work about differences in cells of the SIP syncytium of patients with Hirschsprung disease as well as presenting her awesome imaging work. @INMLAB @HRM_MIPS @MIPS_DDB
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@perera_nimna sharing her work looking at exercise and the proteome of the heart and peripheral EVs in a mouse model of obesity. A brilliant description of cardiac function and how we measure diastolic function of the heart @MIPS_DDB @HRM_MIPS
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Alex kicking off our inaugural 3MT competition with his talk Investigating mitochondrial targeted therapies in cardiomyopathy
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Next up Maleesha takes us on a trip with her 3MT elucidation pharmacologically relevant ligand at the 5HT2CR in the treatment of substance use disorders
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Now Jasmin takes us through her 3MT Dual therapy at the M4 muscarinic receptor for the treatment of schizophrenia
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@AnnabelVarvara gives us a history lesson with her discussion of Darwin’s finches and how the theory of evolution may help our understanding of cancer progression with her 3MT Environment influences Survival
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@LuakKang shares with us the importance of looking after our gut micro biome army for overall health of our body
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Michelle shares with us how we can light up the inside of our cells to see what is inside and what these key proteins are doing
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Ting teaches us how cleaning up inflammatory states in our body may improve symptoms in patients with pulmonary hypertension.
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Isabella explains how we can find the completing puzzle piece for orphan receptors where we don’t know the endogenous ligand with her talk the mysterious life of receptors.
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@ChantelMastos describes how locations specific cellular signalling may be like ordering your oat latte overseas! Different responses to the same request in different locations.
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Selena is flipping the switch with her talk switching on FPR2 on macrophages in the right way: Turning culprits into helpers.
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@ToveyJack sharing how we can use Cryo-EM to develop a pipeline for understanding allosteric modulation of receptors
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My turn now! Had an absolute ball sharing my work on my favourite cells, the gamma delta T cells! Always a special experience to share my work with my @MIPS_DDB peers. Hope you’re all convinced that gamma delta T cells are in fact the coolest. @INMLAB @HRM_MIPS
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Now Cameron is up discussing his work on optimising the structural determination of the Amylin receptor. A great talk discussing optimisation of the protocol and trouble shooting limitations. @MIPS_DDB @TracyMJosephs
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@jaideepsingh84 presents an awesome talk about his work in mechanisms of end organ damage hypertension.

Sep 9, 2022 · 5:21 AM UTC

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@Endymiomatic sharing some of the difficulties associated with CryoEM protocols. An honest discussion if some of the key pain points of the protocol as well as an excellent walk through of the optimisation process.
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Kicking off out final session of the day is @GraceMennen discussing RAMPS and their effects on CGRP and AM receptor families. @MIPS_DDB @HRM_MIPS
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Next up is @david_nash1 from @CNI_lab sharing his study into the impacts of radiotherapy on sympathetic nervous system density in tumours. Some awesome imaging shown here too!
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Final talk for the day is @AbhipreeSharma sharing her study into the sex differences in risk of cardiovascular events in patients with T2D taking SGLT2 inhibitors and GLP1A. An awesome showcase of work @HRM_MIPS @MIPS_DDB
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Overall the future of drug discovery is very bright. Outstanding talks and posters from all students. What a wonderful showcase of some talented young scientists 👩🏼‍🔬 . Congratulations to our award winners @TerranceLamm @AnnabelVarvara and @NS_Mahdavian. Thats a wrap! @MIPS_DDB
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