avidresearch retweeted
𝐖𝐞𝐞𝐤 𝐢𝐧 𝐑𝐞𝐯𝐢𝐞𝐰: Grail scored an FDA advisory committee win while numerous clinical readouts had a big impact this week. Here's your week in review. $GRAL $CMPX $ACAD $VKTX $CLDX
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Don’t understand why biotechs have to be so sensitive to interest rates. Feels like an old playbook that needs to be retired. $XBI $BBC
Yes, your multi-billion peak sales estimate bios $ABVX $CYTK $BBIO are overvalued with rates at 5%. $TEM $TWST at an optimistic 50x 2030 ebitda are not.
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This will consume every one’s Monday
$KOD to Report Topline Data from DAYBREAK Pivotal Phase 3 Study of Zenkuda and KSI-501 in Patients with Wet Age AMD on Monday
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Version number 234
$SPY IRAN GAVE US HORMUZ REOPENING TERMS VIA QATAR — AXIOS SOURCES - AXIOS
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avidresearch retweeted
We estimate 20M U.S. adults are on a GLP-1, which is quite low considering the 41M Americans w/ Type Il diabetes & 106M with Obesity. With lower prices, expanded access & new drugs, we believe the market can essentially double by 2030, with the potential to 5x. $LLY $NOVO $VKTX
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Many SMID biotechs charts look like WTF. Don’t look at $XBI $QQQ $SPY They completely mask the carnage in mid caps.
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Impressive!
$KYTX Clean confirmation that this one time therapy is durable Median T25FW improvement was 46% at week 16 and 49% at month 12, and 95% of patients who hit a clinically meaningful improvement at the primary analysis kept it. 92% remained free of chronic immunotherapies for SPS
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Indexes are pretty useless.
Cringy 😬 363 New Lows to 26 New Highs
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$MRNA went straight up a few days after it issued convertibles. Market works in funny ways.
$VKTX Another one using convertibles. Are they trying to become Moderna 2.0? It depends on the terms. Interesting!
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$GOSS if this gets approved, will be one heck of a turnaround story. The drug works, just got messed up by some sites in LatAm.
$GOSS Gossamer Bio Submits New Drug Application to U.S. FDA for Seralutinib for the Treatment of Pulmonary Arterial Hypertension biopharmcatalyst.com/company…
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avidresearch retweeted
Jeffries $VKTX 17.5 mg 33 wk 22% plc adjusted wt loss is one of the strongest injectable dataset reported to date.
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Portfolio 🩸🩸🩸🩸
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Any of my shitcos in it ??
JUST IN: Morgan Stanley employee accidentally leaks confidential internal list of more than 100 potential deals.
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$MRNA trading at $74B with only 50% rights to the PCV (long way to go before it extends beyond melanoma) $VKTX at $4.6B with 100% rights to a drug that is arguably better than Zepbound and Reta. Some f*cd up market efficiency.
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Initially was skeptical thinking they used tafamids subjects from 2020-2024 (before acoramidis approval) which would introduce a large bias but they only included tafamidis subjects from recent years. Impressive $BBIO
$BBIO BridgeBio Pharma Inc. - Acoramidis Demonstrates Real-World Benefit Versus Tafamidis in ATTR-CM, Reducing Risk of Clinical Worsening investor.bridgebio.com/news/…
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