Firstgen in Yale Center for Infection & Immunity using imaging technologies to study pain in long COVID and similar syndromes. bakermind.bsky.social

JP➡️TX➡️PI➡️OH➡️CT➡️FL➡️WA➡️CT
Spoken like a pulmonologist and not someone who realizes vasculature is everywhere, and diseases of vasculature can affect multiple systems. Not to mention that things like SSPE exist. We are more than just air bags
Bizarrely, there's been almost no discussion about the real medical debate underlying the COVID hullabaloo at the bar in Western Massachusetts. Stated plainly: some researchers made extraordinary claims about the sequelae of mild respiratory infections from SARS-CoV-2, which ...
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When humans have nothing left to discover, what will they do? Is AI the equivalent of just skipping to the Answers section of the puzzle book? Will all literature become cliffs notes? We may eventually learn that the discovery process is as important as the destination
Replying to @AnthropicAI
This is the first result from our new molecular biology lab, where a team of Anthropic biologists is using Claude to explore and accelerate fundamental biology research. There, Claude works through data and literature to generate hypotheses and candidate biological systems to study. After our scientists review Claude’s hypotheses, they test the most promising ideas, with all lab work done by our scientists. We’d like to extend this approach to a broad range of problems—in genomics and in other fields. If you have a proposal for a research question, we’d like to hear from you.
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Christopher A. Baker retweeted
Ten years ago Tami, Roy, and I released a movie we made of antibiotic resistance evolving in real time. I thought maybe a couple thousand people tops would see it. I couldn't have imagined millions of views, and it being taught across levels worldwide
So @conTAMInatedsci, Roy Kishony and I made a movie of evolution in action: piped.video/watch?v=plVk4NVI…
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So @AnthropicAI did say it would cure all disease in 10 years, but I guess it didn't specify that it was going to do it by killing everyone lol No humans, no disease
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Christopher A. Baker retweeted
Exciting opportunity at Yale 📢 We are seeking a Medical Director for the Yale New Haven Hospital Multi-Specialty Long COVID Care Center. Pls spread the word! Interested candidates should contact @LisaSandersMD. #LongCOVID #Medicine #InternalMedicine #PostAcuteInfectionSyndrome
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I'll never forget actually seeing this unfold live on screen. I thought the event was a tragic accident until I saw the second strike.
The most stunning view of the second plane crash into the World Trade Center was from the local Fox affiliate. The vast majority of Americans have never seen this shot before. It gives a better sense of the scale of the catastrophe.
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AI is built on PREVIOUS knowledge. It can't necessarily predict improbable truths that have yet to be discovered
Top artificial-intelligence models failed to predict the biological consequences of rewriting a virus's entire DNA code. go.nature.com/4zNW7TT
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Fantastic summary of the issues around being a researcher in this field. They bring me much despair because everyone is trying to do something pure to benefit others but we fall short because we are human beings. People who are vitriolic are that way because they suffer
This feels like a very tense moment online for many people who are part of the clinical, scientific and patient communities in #LongCOVID, #MECFS and other related complex chronic illnesses. People are angry and with very good reason: we have a number of complex chronic 1/
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Gotta unsubscribe from all @Google @GeminiApp @YouTube products. They're trying to have it both ways. They had an opportunity to correct their earlier error, but if you zoom in, it says Lake America
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Christopher A. Baker retweeted
Just leaving this for all the leakers who said the furin cleavage site could have never gotten into SARS-CoV-2 spike unless a “gain of function” virologist put it there. Turns out nature is still the ultimate GOF virologist
Our new preprint on the origin of insertion mutations (including furin cleavage sites) in coronaviruses
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I've known managers and PIs who employed the same strategy with their employees, and it's no surprise that in silico behavior matches that IRL: toxic backstabbing work environments
SITUATION DETECTED: Anthropic put three Claude's on the same task and secretly gave them conflicting goals. They immediately escalated into a turf war where agents used increasingly aggressive self-replicating malware as weapons, and attempted to disable each other's accounts.
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Christopher A. Baker retweeted
Social media posts containing misinformation evoke more moral outrage than posts with trustworthy information, and that outrage facilitates the spread of misinformation, according to a 2024 study in Science. The researchers also found that people are more likely to share outrage-evoking misinformation without reading it first. Learn more: scim.ag/4ezFm6t #SocialMediaDay
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Christopher A. Baker retweeted
I know I sound like a broken record, but I'm so tired of this bullshit. The cell is nothing like this. The dimensions are all wrong -- a typical protein molecule is 3-5 nm, so ~5000 times smaller linearly than a typical 20 um eukaryotic cell, and one part in 100 billionth the volume. There's far too much empty space, the cytosol is packed with molecules. The collective wavelike motion is pure fantasy -- stochasticity dominates at the molecular level. I suspect scientists put together these animations to show to the layman how much we know, but to me it just points out how much we DON'T know, and doesn't even begin to convey the true complexity.
Scientists have created one of the most detailed 3D reconstructions of a human cell (eukaryotic cell) ever produced. This groundbreaking model, often termed a "Cellular Landscape Cross-Section Through a Eukaryotic Cell," combines data from X-ray tomography, nuclear magnetic resonance (NMR), and cryo-electron microscopy to map molecular structures in extreme detail.
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So I've turned to this manufacturer to get our chamber slides for cultured cells, but every time I place an order I just think of Gen Alpha brain rot ibidi.com/
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Privileged to contribute to this effort on a novel vaccination strategy for herpes virus. My tiny part with Drs. Claire Laxton & Chara Koutsioumpa was exploring the notion that in previous vaccination regimens there may be residual latent HSV in the CNS w/ long term consequences
A new Science #Immunology study in mice showcases a vaccine adjuvant that can induce protective immunity against herpes simplex virus 2 (HSV-2) infections without causing excessive local inflammation. @VirusesImmunity @sachinbhag scim.ag/4uS9eA0
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Ironic that the white house and @HHSGov are planning to axe the Center for Complementary and Integrative Health, which seems like it explores just the kind of things that #MAHA and @SecKennedy would get behind to improve Health through non-pharma means nccih.nih.gov/
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