Neuroscientist | Assoc Professor, Feinstein Institutes @NorthwellHealth @ZuckerSOM | Neuro-immune interactions, bioelectronic medicine, IBD, cancer | Views mine

Manhasset, New York, USA
We are only one month away from the 7th Bioelectronic Medicine Summit in NYC! Seats are selling fast, but there are still spots remaining. Reserve your seat TODAY to hear the latest developments, discoveries, and translational advances in this rapidly growing field of medicine! #2026BEMsummit @NorthwellHealth Many thanks to our Participating Sponsors: GOLD @SetPointMed , SILVER @cognitotx BRONZE: @neuvotion, @Medtronic, @BlackrockNeuro_ @Novocure, @Verasonics, @SpringerNature, Microdul AG, @ActuatedMedical Sept 28-29th, Chelsea Piers, NYC. bemsummit.org/
4
6
346
Excited to share our new review in @JExpMed where we explore how the vagus nerve acts as a two-way communication highway between the nervous and immune systems. We cover how vagal sensory neurons encode cytokines, how different efferent pathways control immunity, and what's next for bioelectronic medicine now that VNS is FDA-approved for RA. Vagal neuroimmune circuits will be key to developing the next generation of biomarkers and therapies to treat and control inflammation!
New Review: Tomás S. Huerta, @KevinJTraceyMD, Isaac M. Chiu & @changsbrain review the organization & function of vagal neuroimmune circuits, from afferent cytokine sensing to organ-specific efferent immune control. hubs.la/Q04ykWBh0 #BioelectronicMedicine #Neuroimmunology
1
7
22
1,436
Eric H Chang retweeted
Speaking With The Mind | Neuralink piped.video/_j806JHhCRo?is=ZFcv… via @YouTube Neuralink has been a game changer as I battle ALS! Please consider supporting me as we Walk to Defeat ALS finding a cure and supporting those currently suffering! Walkers to show support on 10/3, or donations in any amount make a difference! secure2.convio.net/alsa/site… Want to learn more about my journey with Neuralink you can follow me on TikTok @mandabot33 or on X @BluetoothTerry Lori Bush Mandable Catie Mandable Kiri Mandable The ALS Association #Neuralink #ALSawareness #BCI piped.video/_j806JHhCRo?is=DlE2…
132
208
2,142
578,331
Eric H Chang retweeted
🚨 #UPDATE: NBC reporter Eliana Moreno was killed in the Los Angeles news helicopter crash, less than a year after getting engaged. Moreno, 38, had announced her engagement to Robert Barrientos on October 28, 2025. She was a veteran aerial reporter known to viewers as “Eli in the Heli,” covering breaking news from the sky across Southern California. She and pilot George Marciniw were among the three people killed in the crash while NewsChopper 4 was covering a nearby Metro bus wreck. Just absolutely heartbreaking. RIP, Eliana and George Marciniw. 🕊️
39
180
5,561
609,427
SPARC has closed. Its stated purpose: "accelerate development of therapeutic devices that modulate electrical activity in nerves to improve organ function." Here Patel and colleagues lay out what a decade bought: over $350 million, close to 100 projects, 500 papers, 300 open datasets, cross-species vagus maps, ASCENT for modeling stimulation, safety models now used in FDA submissions, open implant platforms. All of it public. SPARC was a big win for bioelectronic medicine. But was it a big enough win, and where are we today? We know very little more about translating this technology to the millions of patients who need it. We have precious few randomized, well powered, controlled trials of implanted VNS or taVNS in people suffering the complications of inflammation. That may not have been SPARC's stated mission. But the basic anti-inflammatory mechanisms were already well established when the program began. We need to move faster from mechanism to therapy. The obstacles are real. As a cofounder of SetPoint Medical, I know them well. So what are the solutions? Where are the new paths to moving faster? Should we accelerate studies of approved devices to expand their indications? Should we run well designed trials of the over-the-counter devices to get answers to simple questions about wellness and effectiveness? There is a fantastic opportunity for new entrants with new ideas. Who are you, and what are your ideas? link.springer.com/article/10…
10
26
4,637
Eric H Chang retweeted
If you're on the frontier, you are going to see things first, at their lowest resolution - they will seem different and uncomfortable...to the rest of the world. To most others, who receive only delayed second-hand accounts, they will seem unreal. There is courage in reporting what you find, as you find it. Each of us has experienced pushback from our colleagues, which is offered (mostly) with care and concern. But the risk of being wrong cannot outweigh the benefit of a potential solution or a source of inspiration. Everything we now hold as concrete started as a simple observation or fleeting idea. Keep pushing forward knowing that the pushback is a necessary part of the process. (A lesson I'm still learning).
Here it is - the official, revised, peer-reviewed version of my Platonic Space paper. mdpi.com/2409-9287/11/5/161 Of all the many unpopular positions I’ve taken over the decades - bitter controversies around the origin of left-right asymmetry in embryogenesis, bioelectricity and genetics, diverse intelligence, etc., this one has by far generated the most pushback: serious (grateful for those!) and energetic attempts to move me to other views, pleas to just drop it and not talk about it (for several different reasons), nasty emails and accusations, impacts on reviews of papers that have nothing to do with this, etc. Kind of amazing to me how incendiary this is. What can I say... Our job is to call it as we see it, and right now for me, this is it. Apologies to collaborators and colleagues for any shrapnel! Time will tell if this pans out or not; I've placed my bets. And btw, if you think this stuff is weird and uncomfortable, just wait… There’s much more on the way. The knob turns slowly but as long as the data keep coming, I'm going to say what I think it all means and follow it to the next steps it enables. Buckle up!
6
15
186
7,929
Eric H Chang retweeted
I've heard a rumor that someone has solved the figures-jumping-around-in-a-Word-doc problem…
13
15
287
18,790
Eric H Chang retweeted
The operating room is still surprisingly 2D. The patient isn’t. That mismatch is starting to disappear. Great feature on @medivis_ai from @Sachin_and_Adam. Glad to contribute my perspective on AR, spatial computing, and what the next generation of neurosurgery may look like.
Standing in front of a human spine rendered in 3D with the software guiding the surgery, @Sachin_Shah_ calls it the most incredible technology moment of his career, and @RandyDAmico_MD says once surgeons see it, it's never going away. "I'm standing here right now looking at a human spine in 3D, and the software is actually guiding me on how to perform surgery on the spine, which is probably the most incredible moment I've had in technology my whole career. My brother actually had a surgery on his spine about 10 years ago that was highly risky, and technology like this makes that feel a lot easier to do." "Once surgeons understand what you can accomplish by bringing in the computing power with the visibility, it's never gonna go away, and it'll become a standard without a doubt. We're getting more minimally invasive in what we do. It's absolutely the future. It's not going anywhere."
2
2
374
Eric H Chang retweeted
Sensory neuroimmunology is living up to all of our speculations 10 years ago - itch, pain, autoimmunity, infection, and even cancer will find major unlocks in this field
Sensory neuroimmune interactions at the barrier are reviewed by @itchdoctor and colleagues: mucosalimmunology.org/articl…
1
10
26
2,313
Big news: @dgsomucla is growing our neuroscience community! Our Dept of Neurobiology is hiring new faculty at any career stage, from people just starting their labs to established leaders, working on everything from the genetics of brain disease to how circuits of neurons produce behavior. What excites me most is the range: we're not looking for one type of scientist, we're looking for curious, creative people asking big questions about how the brain works & what goes wrong in disease. Every new lab that joins adds a new piece to the puzzle & a new set of ideas to the community. If you know a brilliant early-career or established neuroscientist who might be a great fit, send them our way! Please repost to help this reach the right people. recruit.apo.ucla.edu/JPF1129…
14
48
12,295
Eric H Chang retweeted
I'll be attending the amazing 7th Bioelectronic Medicine Summit. Let me know if you're planning to attend so that we can say Hi! 👋 Or register now and join me at the event! whova.com/portal/registratio… #2026BEMsummit - via #Whova event app whova.com/portal/registratio…
1
4
493
Eric H Chang retweeted
UChicago Biological Sciences is is hiring muliple faculty in Neuroscience and AI enabled biology. Come join us! The links to the two searches are here: apply.interfolio.com/190757 apply.interfolio.com/190756
19
61
7,741
Eric H Chang retweeted
Scientists have created the first comprehensive map of the human vagus nerve, tracing thousands of individual nerve fibers stretching from the lower brain stem to all major organs. The map might help scientists and doctors more precisely stimulate the nerve as a potential treatment for conditions such as epilepsy, stroke, and inflammatory diseases. Learn more: scim.ag/4wiOIZI @NewsfromScience
6
128
497
61,036
Eric H Chang retweeted
Why is neuroimmunology such a disruptive field? Next week at the annual @medicxi forum - amongst some of the leading biotech innovators, investors, and big pharma executives - I will be talking about how this biology will bend the therapeutic curve via circuit reset, immunologic tuning (via the nervous system), and spatiotemporal specificity.
5
15
1,237
Eric H Chang retweeted
Scientists should spend the time to learn the history of their field. A review can guide you as to the original papers, but then you should actually read the original papers. Surprising things will crop up as a result - including questions that remain unanswered today.
4
10
57
2,800
Eric H Chang retweeted
Wow this new Claude text watermarking is wild
153
447
14,736
2,253,142