Founder, Managing Partner @PanteraCapital – the first investment firm in the U.S. to launch digital currency, early-stage token, and blockchain venture funds.
Dorado Beach
- Tweets 1,803
- Following 226
- Followers 164,698
- Likes 923
Pinned Tweet
Pantera Bitcoin Fund recently achieved an insane milestone – 1,000x.
The post-election surge has taken the fund a further 30% higher. The Fund’s lifetime return is now 131,165% – net of fees and expenses.
My current outlook on #Bitcoin: panteracapital.com/blockchai…
162
246
1,796
206,231
What would an “Ozempic for sleep” look like?
We spend a third of our lives sleeping, yet there has been surprisingly little innovation focused on dramatically improving it.
@mackenziejem is hosting a research day on exactly that question.
RSVP here luma.com/249fnmh6
We're hosting a Research Day on Ozempic for Sleep!
Last year we published in-depth research on sleep frontiers
We're now bringing together the world's top researchers and entrepreneurs pushing the bounds of both basic science and translation
RSVP here: luma.com/249fnmh6
5
1
18
9,450
With memory being a core bottleneck in the Al build out, Mackenzie breaks down what step function technologies could come after HBM
New Post: What Comes After HBM?
It might be crazy to start a new memory company at outrageous highs... but maybe it's just crazy enough
We profile speculative technologies that could lead to:
1) Faster than HBM Access Speeds
or
2) HBM-like Bandwidth with NAND-Like Density
1
1
17
7,728
Dan Morehead retweeted
“AI Agents will choose the fastest, cheapest, most frictionless rails."
@cosmo_jiang sat down with @CoinDesk this morning to share how Pantera views the current market:
- How AI agents accelerate blockchain adoption
- Is the $BTC 4-year cycle still accurate?
- The setup for an onchain rebound into Q4
- Building a fundamentals index with @SPDJIndices
“How many assets can get brought on-chain? We think it could be tens of trillions.”
@CitizensBank's @devinpryan calls Securitize's post-earnings selloff an overreaction and stands by his $15 target. @PanteraCapital's @cosmo_jiang reveals why Bitcoin was left out of the S&P Pantera Digital Asset Index. And, @RobinhoodApp CFO @ShivVerma on opening early-stage investing to retail investors.
Watch Public Keys from the @NYSE with @JennSanasie:
Chapters/Timecodes:
00:00 Welcome to Public Keys
00:29 Securitize Stumbles in First Public Earnings Report
00:50 Citizens' Devin Ryan Joins Public Keys
02:07 From Speculation to Real Blockchain Usage
03:52 Securitize's 26% Selloff and a $15 Price Target
05:29 The Bull and Bear Case for SECZ
06:47 Will the SEC and CFTC Fill the Regulatory Gap?
09:58 What to Watch: BlackRock and Tokenized AUM
12:18 Bitcoin ETFs Post $390M in Weekly Outflows
12:46 13F Filings: Harvard Holds, JPMorgan and Tudor Add
13:06 Ethereum ETFs Snap Five-Week Inflow Streak
13:42 Pantera's Cosmo Jiang on the Market Outlook
16:59 Bitcoin's 42% Discount vs. AI Stocks' Premium
18:26 Blockchain and the Agentic Economy
20:17 Why Solana Leads on AI Agent Activity
21:15 Inside the S&P Pantera Digital Asset Index
25:07 Robinhood Ventures Fund II Debuts on NYSE
26:03 The Risk and Reward of Early-Stage Investing
28:32 How Daily Liquidity for Private Assets Works
30:38 Robinhood Chain, Tokenization and Yield
32:48 Crypto Fear & Greed Index at 31
14
11
54
13,560
Dan Morehead retweeted
AI agents won’t walk into a bank and open a traditional account.
They need digital money. They need crypto.
@dan_pantera: As agentic finance accelerates, crypto becomes essential infrastructure. There is no important future for AI in which crypto is not a core part.
That’s why cryptocurrency itself serves as a powerful hedge and tangential play on the rise of AI agents.
@Alchemy
21
83
155
12,050
Dan Morehead retweeted
From early conviction to institutional adoption, #crypto investing is entering a new phase.
Host of The Bid #podcast, Oscar Pulido, sits down with Robbie Mitchnick of BlackRock and Dan Morehead of Pantera Capital at #LAIF26 to discuss bitcoin’s unique role, market cycles, and how digital assets are evolving investor perspectives.
🎧 Listen: 1blk.co/4wfPF6z
14
19
55
16,461
Dan Morehead retweeted
Beyond the Digital Copy: What's Next for Tokenization?
Our research team developed a new index of 593 assets across a $320B market that reveals how far onchain finance still has to go.
Access the full report here:
panteracapital.com/state-of-…
41
56
238
206,257
Dan Morehead retweeted
Sam Altman @sama joins @cosmo_jiang to discuss why proof of human is necessary in the age of AI.
@masonnystrom also joins to share why Pantera invested in @worldnetwork.
In this episode, they cover:
- AI is advancing faster than Sam expected. The need for proof of human has never been stronger.
- Agents need to move money. Agentic payments are one of Sam's most personally exciting use cases.
- Proof of human as a substrate: driver's licenses, education, and employment credentials all appended to a verified human identity.
- Targeted advertising is the first massive use case as AI agents flood the internet.
- Advertisers will pay a premium for verified human impressions.
- World has 18 million verified humans today with 4 billion smartphone users as the addressable market.
01:27 Sam Altman's Keynote at World’s Lift-Off Event
02:12 Why World Was Built
03:48 Blockchain x AI
04:08 World ID Use Cases
04:47 World's Founding Vision
05:10 World ID Trajectory
05:50 Why Pantera Invested in World
06:45 Sam Altman Saw This Coming
07:10 Proof of Human at Scale
10:12 The Value of Digital Identity
11:11 Agents Need a Human in the Loop
11:42 Scaling to Billions of Users
12:53 Enterprise Partnerships
35
75
421
255,798
🤩SPEAKER ALERT🤩
@dan_pantera, Founder & Managing Partner at @PanteraCapital, is joining us at CoBuild.
The macro investor who went all-in on crypto in 2013 has a new thesis.
📆 April 28
🍕 NYC.
3
8
36
6,781
Dan Morehead retweeted
DAN MOREHEAD on why he thinks equities (AI in particular) are overvalued, & crypto is oversold.
@dan_pantera @PanteraCapital
Full ep:
Youtube: piped.video/watch?v=0q8yJ_Js…
Spotify:open.spotify.com/episode/1bb…
Apple: podcasts.apple.com/gb/podcas…
4
7
21
6,210
Mackenzie published a detailed quantitative analysis of biotech platforms.
Good place to start to understand how platform companies from Moderna with mRNA to Isomorphic with AI reach patients and are valued in markets.
New Post: Quantitative Look at Biotech Platforms
Plenty has been written about bio platform strategy but no one's put numbers around it
We used a whole lotta tokens to compile clinical, partnership + financial data on the 100 most successful public platform biotechs of all time
12
3
22
6,713
AI agents aren't going to go down the street to an ionic column, marble bank to get a normal bank account, and transact in paper money.
They have to use electronic money.
So, as AI agents become more impactful, they have to use blockchain assets and that will just increase the demand for blockchain assets.
We’re witnessing a convergence of AI and crypto.
AI agents can't walk into a bank, open an account, or transact in paper money.
Crypto provides the financial rails for AI agents to exchange value online.
As AI adoption grows exponentially, we believe crypto demand will follow naturally.
@dan_pantera @bloomberg @crypto
30
16
116
17,648
Looking forward to a great conversation with @fundstrat (Tom Lee) today at Ondo Summit at 10:40am EST.
We'll discuss the macro environment, regulation, and the evolution of onchain finance.
Tokenization is inevitable.
“Tokenization has crossed from concept into inevitability, unlocking global liquidity, faster settlement, and broader access.”
Dan Morehead, Pantera Capital. One of many institutional leaders gathering at the Ondo Summit in under 30 days.
20
14
112
15,134
Dan Morehead retweeted
2025 was not a fundamentals-driven year for returns in the crypto markets.
@Cosmo_Jiang outlines key moments from last year that led to a divergence between Bitcoin and the broader token market in our latest blockchain letter.
Here are key insights from 2025
9
145
124
23,659
Huge congratulations to @BitGo and @mikebelshe on this incredible milestone!
@PanteraCapital has supported BitGo since 2014 and we’re excited to see their continued leadership in institutional crypto infrastructure.
Looking forward to all the incredible things yet to come!
Infrastructure for Innovation. It's @BitGo's IPO.
Welcome, @mikebelshe and team!
10
157
122
15,511