StyleX is pretty nice, but it's missing some important things for design systems IMO. One of the best things about Tailwind is that it is a design system. Color tokens, consistent spacing, font sizes, etc. are the default. You can use arbitrary values too but it pushes you away from that.
StyleX is just raw CSS by default – no restrictions. You _can_ create variables like in CSS, but it's not the default, and therefore inconsistency is the default. It's a subtle distinction but it really makes a big difference in how a system is used.