Institute for Cardiovascular Prevention, Munich University Hospital @LMU_Uniklinikum @LMU_Muenchen Institute Director Christian Weber @dfg_public @dzhk_germany
Munich, Bavaria
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IPEK retweeted
📢TOMORROW ‼️
📢Looking forward to our next CRC 1123 Keynote Lecture 🧑🏫by Clément Cochain next week on TREM2+ macrophages in atherosclerosis and MI
ipek-research.com/news-repor…
@dfg_public @SteffensLab @ipekresearch
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IPEK retweeted
📢Looking forward to our next CRC 1123 Keynote Lecture 🧑🏫by Clément Cochain next week on TREM2+ macrophages in atherosclerosis and MI
ipek-research.com/news-repor…
@dfg_public @SteffensLab @ipekresearch
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The #MIAS2025 Symposium in Munich brought together global experts to advance research on #atherosclerosis, #immunity & #metabolism.
🌟Editorial perspective by @NatureCVR @Vesna_Tod and young scientists awards 🎖️Simon Ebert & Robby Zachariah-Tom
#CardiovascularResearch ❤️🩹
📢Registration is open for the International 🗺️#Atherosclerosis Symposium in Munich 🥨, Oct 21–22, 2025! 🧬 Hosted by @dfg_public CRC 1123.
Join top experts🧑🔬👩🔬 for talks, posters & networking!
Abstract deadline: July 31.
➡️Details & sign-up: mias2025.de
#Science
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IPEK retweeted
📢Looking forward to our next CRC 1123 🎓Graduate School Lecture by Florian Gärtner next week
@LMU_Muenchen
on Mechanisms of 3D Cell Migration
ipek-research.com/scrivito/n…
@dfg_public @SteffensLab
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IPEK retweeted
In a new study, researchers find that the chemokine CXCL12 can support the production of red blood cells in mice, suggesting that this pathway could be investigated for the treatment of disorders related to red blood cells.
Learn more in @SciSignal: scim.ag/4kTxFZz
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IPEK retweeted
A preclinical study uncovers a metabolic pathway that offers a target in neuropathic pain, scientists discover how chemokines can support red blood cell production in mice, and more this week in #ScienceSignaling. scim.ag/3HEv8no
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IPEK retweeted
Not all chemokine signaling is about cell migration!
In mouse erythroblasts, CXCL12-bound CXCR4 enters the nucleus to control gene transcription, trigger calcium bursts, and drive red blood cell formation—especially enucleation.
🔗 science.org/doi/10.1126/scis…
#chemokine #CXCR4
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IPEK retweeted
📢Registration is open for the International 🗺️#Atherosclerosis Symposium in Munich 🥨, Oct 21–22, 2025! 🧬 Hosted by @dfg_public CRC 1123.
Join top experts🧑🔬👩🔬 for talks, posters & networking!
Abstract deadline: July 31.
➡️Details & sign-up: mias2025.de
#Science
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IPEK retweeted
#TODAY 🗓️5pm CRC1123 Graduate 🎓Lecture 🧑🏫by Leo Nicolai on #Platelets in acute and chronic #inflammation
➡️ ipek-research.com/news-repor…
@dfg_public @SteffensLab
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IPEK retweeted
📢Looking forward to our next Graduate CRC1123 👩🏫
Lecture Series next week by🗣️Zhifen Chen @TU_Muenchen on Risk 🚨and Resilience Mechanisms for Coronary Artery Disease 🫀🩺 in #Obesity 📏⚖️
ipek-research.com/news-repor…
@dfg_public
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IPEK retweeted
Great emotional week with conferences, defended thesis and meeting old colleagues. Congratulate Dr. @GeorgeShakir on his new achievement. linkedin.com/posts/raquel-gu…
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IPEK retweeted
📢#TODAY Looking forward to our CRC/IRTG 1123
🧑🏫Seminar Series @dfg_public @LMU_Muenchen
🗣️ Slava Epelman @EpelmanLab @UHN_Research @PMunkCardiacCtr @trogersresearch @UofT
📌 Enhancing engineered 🧫heart tissues with macrophages
ipek-research.com/news-repor…
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IPEK retweeted
📢Looking forward to our next joint CRC/IRTG 1123
🧑🏫Seminar Series this week 🗓️@dfg_public @LMU_Muenchen
🗣️ Slava Epelman @EpelmanLab @UHN_Research @PMunkCardiacCtr @trogersresearch @UofT
📌 Enhancing engineered 🧫heart 🫀 tissues with macrophages
ipek-research.com/news-repor…
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IPEK retweeted
📢Looking forward to our next joint CRC/IRTG 1123
🧑🏫Seminar Series next week 🗓️@dfg_public @LMU_Uniklinikum
🗣️ Slava Epelman @EpelmanLab @UHN_Research @PMunkCardiacCtr @trogersresearch @UofT
📌 Enhancing engineered 🧫heart 🫀 tissues with macrophages
ipek-research.com/news-repor…
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IPEK retweeted
Played a minor part but that’s us @CRC1123_Athero
MIF-2 positioned as an atypical chemokine linking vascular inflammation to metabolic dysfunction in atherosclerosis through CXCR4 @naturecomms nature.com/articles/s41467-0…
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IPEK retweeted
Congratulations to Harini Balasubramanian on her Master’s degree - well done! I am proud of you and the work you've done in the lab👩🔬 Looking forward to exciting future work together! @ipekresearch
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IPEK retweeted
CXCL12-CXCR4 axis drives CD8+ T cell plaque infiltration and may play a role in human atherosclerosis @_LauraParma @DucheneJohan @ipekresearch @LarsMaeg @mariedepuydt ahajournals.org/doi/full/10.…
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IPEK retweeted
Very excited to share our latest discoveries revealing the crucial role of the merhyltransferase Ezh2 in T cells during #atherosclerosis 🧬
@AtzlerLab @LutgensEsther @ipekresearch @CRC1123_Athero @dzhk_germany @LMU_Muenchen
Now online @CircAHA
ahajournals.org/doi/full/10.…
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IPEK retweeted
T cells, especially CD8, are recognized to be the main hematopoietic cells in human atherosclerotic plaques.
How are they recruited?
We developed a 3D tissue culture model and found that intraplaque ACKR1+ vessels secrete CXCL12 and recruits CD8 cells.
ahajournals.org/doi/10.1161/…
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IPEK retweeted
Why are ACKR1+ intraplaque neovessels key in atherosclerosis?
These venular vessels express CXCL12 that attracts CD8+ T cells via CXCR4 in the plaque
This may unlock new cardiovascular therapy #Atherosclerosis #Chemokines
Read our study here 👇👇👇
ahajournals.org/doi/10.1161/…
ALT Representative images showing intraplaque ACKR1+ neovessels (ACKR2, blue; CD31, green) producing CXCL12 (red) in human atherosclerotic plaque.
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